N-Acetonylnitropyrazolecarboxylic acids in the selective synthesis of N-acetonyl-3-R-5-nitropyrazolyl-1,2,4-oxadiazoles
Alkylation of isomeric methyl nitropyrazolecarboxylates with bromoacetone followed by acid hydrolysis gave new N -acetonylnitropyrazolecarboxylic acids. A selective synthesis of 3-R-5-( N -acetonylnitropyrazolyl)-1,2,4-oxadiazoles based on the reaction of nitropyrazolecarboxylic acid chlorides with...
Saved in:
Published in: | Russian chemical bulletin Vol. 73; no. 5; pp. 1362 - 1373 |
---|---|
Main Authors: | , , , |
Format: | Journal Article |
Language: | English |
Published: |
New York
Springer US
01-05-2024
Springer Nature B.V |
Subjects: | |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | Alkylation of isomeric methyl nitropyrazolecarboxylates with bromoacetone followed by acid hydrolysis gave new
N
-acetonylnitropyrazolecarboxylic acids. A selective synthesis of 3-R-5-(
N
-acetonylnitropyrazolyl)-1,2,4-oxadiazoles based on the reaction of nitropyrazolecarboxylic acid chlorides with isomeric amidoximes of nitropyrazoles and aminofurazan was developed. The possibility to introduce the second
N
-acetonyl group into di(nitropyrazolyl)-1,2,4-oxadiazoles was studied. |
---|---|
ISSN: | 1066-5285 1573-9171 |
DOI: | 10.1007/s11172-024-4254-2 |