Search Results - "Gusarov, Ivan"

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    Dietary thiols accelerate aging of C. elegans by Gusarov, Ivan, Shamovsky, Ilya, Pani, Bibhusita, Gautier, Laurent, Eremina, Svetlana, Katkova-Zhukotskaya, Olga, Mironov, Alexander, Makarov, Alexander А., Nudler, Evgeny

    Published in Nature communications (15-07-2021)
    “…Glutathione (GSH) is the most abundant cellular antioxidant. As reactive oxygen species (ROS) are widely believed to promote aging and age-related diseases,…”
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    Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics by Gusarov, Ivan, Shatalin, Konstantin, Starodubtseva, Marina, Nudler, Evgeny

    “…Bacterial nitric oxide synthases (bNOS) are present in many Gram-positive species and have been demonstrated to synthesize NO from arginine in vitro and in…”
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    Bacterial Nitric Oxide Extends the Lifespan of C. elegans by Gusarov, Ivan, Gautier, Laurent, Smolentseva, Olga, Shamovsky, Ilya, Eremina, Svetlana, Mironov, Alexander, Nudler, Evgeny

    Published in Cell (14-02-2013)
    “…Nitric oxide (NO) is an important signaling molecule in multicellular organisms. Most animals produce NO from L-arginine via a family of dedicated enzymes…”
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    Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress by Gusarov, Ivan, Pani, Bibhusita, Gautier, Laurent, Smolentseva, Olga, Eremina, Svetlana, Shamovsky, Ilya, Katkova-Zhukotskaya, Olga, Mironov, Alexander, Nudler, Evgeny

    Published in Nature communications (19-06-2017)
    “…A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects…”
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    NO-Mediated Cytoprotection: Instant Adaptation to Oxidative Stress in Bacteria by Gusarov, Ivan, Nudler, Evgeny, Snyder, Solomon H.

    “…Numerous sophisticated systems have been described that protect bacteria from increased levels of reactive oxygen species. Although indispensable during…”
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    Mechanism of biofilm-mediated stress resistance and lifespan extension in C. elegans by Smolentseva, Olga, Gusarov, Ivan, Gautier, Laurent, Shamovsky, Ilya, DeFrancesco, Alicia S., Losick, Richard, Nudler, Evgeny

    Published in Scientific reports (02-08-2017)
    “…Bacteria naturally form communities of cells known as biofilms. However the physiological roles of biofilms produced by non-pathogenic microbiota remain…”
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    Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages by Shatalin, Konstantin, Gusarov, Ivan, Avetissova, Ekaterina, Shatalina, Yelena, McQuade, Lindsey E, Lippard, Stephen J, Nudler, Evgeny

    “…Phagocytes generate nitric oxide (NO) and other reactive oxygen and nitrogen species in large quantities to combat infecting bacteria. Here, we report the…”
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    Bacterial Nitric-oxide Synthases Operate without a Dedicated Redox Partner by Gusarov, Ivan, Starodubtseva, Marina, Wang, Zhi-Qiang, McQuade, Lindsey, Lippard, Stephen J., Stuehr, Dennis J., Nudler, Evgeny

    Published in The Journal of biological chemistry (09-05-2008)
    “…Bacterial nitric-oxide (NO) synthases (bNOSs) are smaller than their mammalian counterparts. They lack an essential reductase domain that supplies electrons…”
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    The Mechanism of Intrinsic Transcription Termination by Gusarov, Ivan, Nudler, Evgeny

    Published in Molecular cell (01-04-1999)
    “…In bacteria, an intrinsic transcription termination signal appears in RNA as a hairpin followed by approximately eight uridines (U stretch) at the 3′ terminus…”
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    Protein S-Nitrosylation: Enzymatically Controlled, but Intrinsically Unstable, Post-translational Modification by Gusarov, Ivan, Nudler, Evgeny

    Published in Molecular cell (01-02-2018)
    “…Reports by Seth et al. (2018) and Wolhuter et al. (2018) in this issue of Molecular Cell highlight the enzymatic synthesis, functionality, and propagation of…”
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    Glycogen at the Crossroad of Stress Resistance, Energy Maintenance, and Pathophysiology of Aging by Gusarov, Ivan, Nudler, Evgeny

    Published in BioEssays (01-09-2018)
    “…Glycogen is synthesized and stored to maintain postprandial blood glucose homeostasis and to ensure an uninterrupted energy supply between meals. Although the…”
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    S-nitrosylation signaling in Escherichia coli by Gusarov, Ivan, Nudler, Evgeny

    Published in Science signaling (12-06-2012)
    “…Most bacteria generate nitric oxide (NO) either aerobically by NO synthases or anaerobically from nitrite. Far from being a mere by-product of nitrate…”
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    Control of Intrinsic Transcription Termination by N and NusA: The Basic Mechanisms by Gusarov, Ivan, Nudler, Evgeny

    Published in Cell (16-11-2001)
    “…Intrinsic transcription termination plays a crucial role in regulating gene expression in prokaryotes. After a short pause, the termination signal appears in…”
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    Sensing Small Molecules by Nascent RNA: A Mechanism to Control Transcription in Bacteria by Mironov, Alexander S., Gusarov, Ivan, Rafikov, Ruslan, Lopez, Lubov Errais, Shatalin, Konstantin, Kreneva, Rimma A., Perumov, Daniel A., Nudler, Evgeny

    Published in Cell (27-11-2002)
    “…Thiamin and riboflavin are precursors of essential coenzymes—thiamin pyrophosphate (TPP) and flavin mononucleotide (FMN)/flavin adenine dinucleotide (FAD),…”
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    Nitric oxide produced by bacteria extends Caenorhabditis elegans lifespan by Gusarov, Ivan, Smolentseva, Olga, Gautier, Laurent, Nudler, Evgeny

    Published in Nitric oxide (15-07-2012)
    “…Nitric oxide (NO) is an important signaling molecule in multicellular organisms. Most animals produce NO from l-arginine by a family of dedicated enzymes known…”
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