Search Results - "Gurupadaswamy, H.D."
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DAO-9 (2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazole) exhibits p53 induced apoptogenesis through caspase-3 mediated endonuclease activity in murine carcinoma
Published in Biomedicine & pharmacotherapy (01-07-2014)“…Abstract One of the main strategies to inhibit the tumor growth is to promote the biochemical events leading to DNA degradation, which would eventually…”
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Synthesis and evaluation of 2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazoles as anti-cancer agents
Published in European journal of medicinal chemistry (01-05-2013)“…A series of 2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazoles 9a–j were obtained via multistep synthesis from hydroxybenzophenones 4a–e. The cytotoxicity of…”
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Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development
Published in Bioorganic chemistry (01-04-2017)“…[Display omitted] •A series of novel morpholine conjugated benzophenone analogues 8a-j were synthesized.•Synthesized compounds were characterized by spectral…”
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Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton’s lymphoma
Published in Bioorganic chemistry (01-04-2016)“…[Display omitted] •Novel benzophenone tagged pyridine derivatives 8a–l were synthesized in good yield.•All the synthesized compounds were characterized by…”
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Synthesis and larvicidal properties of benzophenone comprise indole analogues against Culex quinquefasciatus
Published in Drug invention today (01-12-2013)“…With the increase of resistance to conventionally used existing synthetic insecticides, vector management has become extremely challenging. Hence more…”
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