Search Results - "Gurunath, Surampalli"
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A comparative physicochemical and pharmacological evaluation of dexamethasone sodium phosphate and betamethasone sodium phosphate mucoadhesive gels for the treatment of oral submucous fibrosis in rats
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2022)“…Abstract The present study is aimed to formulate steroidal oral mucoadhesive gels of dexamethasone sodium phosphate and betamethasone sodium phosphate. Six gel…”
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Novel tablet formulation of amorphous candesartan cilexetil solid dispersions involving P-gp inhibition for optimal drug delivery: in vitro and in vivo evaluation
Published in Drug delivery (01-09-2016)“…The aim of this study was to develop a novel tablet formulation of amorphous candesartan cilexetil (CAN) solid dispersion involving effective P-gp inhibition…”
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3
Nephroprotective effects of honokiol in a high-fat diet-streptozotocin rat model of diabetic nephropathy
Published in Life sciences (1973) (01-05-2023)“…Diabetic nephropathy (DN) is the foremost basis of end-stage kidney failure implicating endoplasmic reticulum (ER) stress and dysregulation of Rho kinase/Rock…”
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Arbutin protects brain against middle cerebral artery occlusion-reperfusion (MCAo/R) injury
Published in Biochemical and biophysical research communications (05-11-2021)“…Focal ischemia causes irreversible brain damage if cerebral blood flow is not restored promptly. Acute phase excitotoxicity and pro-oxidant and inflammatory…”
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Oral bioavailability and intestinal absorption of candesartan cilexetil: role of naringin as P-glycoprotein inhibitor
Published in Drug development and industrial pharmacy (01-01-2015)“…Abstract Objective: The aim of the study is to explore the pharmacokinetic behavior of candesartan solid dispersions prepared by different pharmaceutical…”
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In vitro and in vivo effects of morin on the intestinal absorption and pharmacokinetics of olmesartan medoxomil solid dispersions
Published in Drug development and industrial pharmacy (04-05-2017)“…Purpose: In-situ evaluation to corroborate morin effects on the intestinal absorption and pharmacokinetic behavior of freeze-dried OLM-loaded solid dispersions…”
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Safety evaluation of naringenin upon experimental exposure on rat gastrointestinal epithelium for novel optimal drug delivery
Published in Drug delivery (12-02-2016)“…To assess the effect of naringenin on the intestinal biochemical composition, function and histology for gastrointestinal toxicity since it has not yet been…”
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Corroboration of naringin effects on the intestinal absorption and pharmacokinetic behavior of candesartan cilexetil solid dispersions using in-situ rat models
Published in Drug development and industrial pharmacy (01-07-2015)“…Abstract Objective: The aim of this study was to corroborate the effects of naringin, a P-glycoprotein inhibitor, on the intestinal absorption and…”
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Comprehensive cytotoxic evaluation of morin, a bioflavonoid against verapamil on rat gastrointestinal epithelium for novel pharmaceutical application involving P-glycoprotein inhibition
Published in Journal of pharmacy and pharmacology (01-08-2015)“…Objective In this study, a comprehensive and comparative cytotoxic evaluation of morin against verapamil on rat intestinal epithelium as P‐gp inhibitors…”
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Amorphous solid dispersion method for improving oral bioavailability of poorly water-soluble drugs
Published in Journal of pharmacy research (01-04-2013)“…Amorphous solid dispersions are one of the most promising strategies to improve the oral bioavailability of sparingly water-soluble drugs. Drug particle size…”
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