Search Results - "Gurtner, G. C."
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Wound healing and regenerative strategies
Published in Oral diseases (01-09-2011)“…Oral Diseases (2011) 17, 541–549 Wound healing is a complex biological process that affects multiple tissue types. Wounds in the oral cavity are particularly…”
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Impact of surgical innovation on tissue repair in the surgical patient
Published in British journal of surgery (01-01-2015)“…Background Throughout history, surgeons have been prolific innovators, which is hardly surprising as most surgeons innovate daily, tailoring their intervention…”
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Quantifying migration and polarization of murine mesenchymal stem cells on different bone substitutes by confocal laser scanning microscopy
Published in Journal of cranio-maxillo-facial surgery (01-12-2010)“…Summary Introduction Cell migration is preceded by cell polarization. The aim of the present study was to evaluate the impact of the geometry of different bone…”
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Low Density Lipoprotein Undergoes Oxidative Modification in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1989)“…It has been proposed that low density lipoprotein (LDL) must undergo oxidative modification before it can give rise to foam cells, the key component of the…”
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Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation
Published in Genes & development (01-01-1995)“…Vascular cell adhesion molecule-1 (VCAM-1) is expressed on vascular endothelium in a variety of inflammatory conditions and mediates leukocyte recruitment from…”
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Bone formation and degradation of a highly porous biphasic calcium phosphate ceramic in presence of BMP-7, VEGF and mesenchymal stem cells in an ectopic mouse model
Published in Journal of cranio-maxillo-facial surgery (01-09-2010)“…Summary Introduction Angiogenesis and mesenchymal stem cells (MSCs) promote osteogenesis. The aim of the present study was to evaluate whether bone…”
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Effect of carbon dioxide pneumoperitoneum on bacteraemia and endotoxaemia in an animal model of peritonitis
Published in British journal of surgery (01-06-1995)“…Laparoscopy is increasingly used in conditions complicated by peritonitis. A theoretical concern is that carbon dioxide pneumoperitoneum may increase…”
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Two-team synchronous oesophagectomy
Published in British journal of surgery (01-11-1994)“…Between 1984 and 1992, 131 patients underwent two-team synchronous oesophagectomy for carcinoma. Some 95 per cent of tumours were successfully resected by this…”
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Immunotargeting of Liposomes to Activated Vascular Endothelial Cells: A Strategy for Site-Selective Delivery in the Cardiovascular System
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-1997)“…Endothelial-selective delivery of therapeutic agents, such as drugs or genes, would provide a useful tool for modifying vascular function in various disease…”
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Reduction mammoplasty improves breast conservation therapy in patients with macromastia
Published in The American journal of surgery (01-03-2001)“…Background: Macromastia has been considered a contraindication to breast conservation therapy because of difficulties with radiation therapy. This study…”
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Improved static lung preservation with corticosteroids and hypothermia
Published in The Journal of heart transplantation (01-09-1988)“…With methylprednisolone as a chemical inhibitor of leukocytes, extended preservation was conducted with an isolated rabbit lung model. The heart-lung blocks of…”
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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
Published in Nature medicine (01-08-2004)“…The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly understood. The chemokine stromal cell-derived factor-1 (SDF-1 or…”
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Homing to Hypoxia: HIF-1 as a Mediator of Progenitor Cell Recruitment to Injured Tissue
Published in Trends in cardiovascular medicine (01-02-2005)“…The identification of bone marrow-derived endothelial progenitor cells has altered our understanding of new blood vessel growth and tissue regeneration…”
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Topical Vascular Endothelial Growth Factor Accelerates Diabetic Wound Healing through Increased Angiogenesis and by Mobilizing and Recruiting Bone Marrow-Derived Cells
Published in The American journal of pathology (01-06-2004)“…Diminished production of vascular endothelial growth factor (VEGF) and decreased angiogenesis are thought to contribute to impaired tissue repair in diabetic…”
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Adult vasculogenesis occurs through in situ recruitment, proliferation, and tubulization of circulating bone marrow–derived cells
Published in Blood (01-02-2005)“…Ischemia is a known stimulus for vascular growth. Bone marrow (BM)–derived endothelial progenitor cells (EPCs) are believed to contribute to new blood vessel…”
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Quantitative and reproducible murine model of excisional wound healing
Published in Wound repair and regeneration (01-07-2004)“…The goal of animal wound healing models is to replicate human physiology and predict therapeutic outcomes. There is currently no model of wound healing in…”
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Advances in head and neck reconstruction
Published in Plastic and reconstructive surgery (1963) (01-09-2000)“…Head and neck deformities, which can be caused by trauma, congenital defects, infections, or neoplasms, produce a stereotypical constellation of functional and…”
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Cellular Dysfunction in the Diabetic Fibroblast: Impairment in Migration, Vascular Endothelial Growth Factor Production, and Response to Hypoxia
Published in The American journal of pathology (01-01-2003)“…Although it is known that systemic diseases such as diabetes result in impaired wound healing, the mechanism for this impairment is not understood. Because…”
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