Search Results - "Gursky, O."

Causal link between serum amyloid A and oxidative damages to high-density lipoprotein by Jayaraman, S, Haupt, C, Gursky, O

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Thermal stability of human plasma LDL(−): A paradoxical behavior of LDL aggregation by Rull, A, Jayaraman, S, Rivas, A, Pérez Cuellar, M, Ordóñez Llanos, J, Sánchez Quesada, J.L, Gursky, O

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Thermal unfolding of human high-density apolipoprotein A-1: implications for a lipid-free molten globular state by Gursky, O. (Boston University School of Medicine, Boston, MA.), Atkinson, D

“…Apolipoprotein A-1 (apoA-1) in complex with high-density lipoprotein is critically involved in the transport and metabolism of cholesterol and in the…”
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Solution Conformation of Human Apolipoprotein C-1 Inferred from Proline Mutagenesis:  Far- and Near-UV CD Study by Gursky, Olga

“…Solution structure of lipid-free apolipoprotein C-1 (apoC-1, 6.6 kD) was analyzed by circular dichroism (CD) of 15 mutants containing single Pro or Ala…”
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Probing the conformation of a human apolipoprotein C‐1 by amino acid substitutions and trimethylamine‐N‐oxide by Gursky, Olga

“…To test, at the level of individual amino acids, the conformation of an exchangeable apolipoprotein in aqueous solution and in the presence of an osmolyte…”
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Heparin binding triggers VLDL remodeling by circulating lipoprotein lipase: Relevance to VLDL functionality in health and disease by Jayaraman, S., Pérez, A., Miñambres, I., Quesada, J.L.S., Gursky, O.

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Probing the Lipid-Free Structure and Stability of Apolipoprotein A-I by Mutation by Gorshkova, Irina N, Liadaki, Kalliopi, Gursky, Olga, Atkinson, David, Zannis, Vassilis I

“…To probe the secondary structure of the C-terminus (residues 165−243) of lipid-free human apolipoprotein A-I (apoA-I) and its role in protein stability,…”
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Impact of weight loss after a bariatric surgery on the low-density lipoprotein-proteoglycan interaction by Jayaraman, S., Pérez, A., Miñambres, I., Sanchez-Quesada, J.L., Gursky, O.

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High‐ and low‐temperature unfolding of human high‐density apolipoprotein A‐2 by Gursky, Olga, Atkinson, David

“…Human plasma apolipoprotein A‐2 (apoA‐2) is the second major protein of the high‐density lipoproteins that mediate the transport and metabolism of cholesterol…”
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Serum amyloid a spontaneously solubilizes diverse phospholipids and forms lipoproteins by Jayaraman, S., Gantz, D., Haupt, C., Faendrich, M., Gursky, O.

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Conformational changes in cubic insulin crystals in the pH range 7–11 by Gursky, O., Badger, J., Li, Y., Caspar, D.L.

“…To determine the effect of variations in the charge distribution on the conformation of a protein molecule, we have solved the structures of bovine cubic…”
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Apolipoprotein structure and dynamics by Gursky, Olga

“…This review highlights recent advances in structural studies of exchangeable human apolipoproteins and the insights they provide into lipoprotein action in…”
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Monitoring protein aggregation during thermal unfolding in circular dichroism experiments by Benjwal, Sangeeta, Verma, Shikha, Röhm, Klaus‐Heinrich, Gursky, Olga

“…Thermal unfolding monitored by spectroscopy or calorimetry is widely used to determine protein stability. Equilibrium thermodynamic analysis of such unfolding…”
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Stereospecific Dihaloalkane Binding in a pH-Sensitive Cavity in Cubic Insulin Crystals by Gursky, Olga, Fontano, Eric, Bhyravbhatla, Balaji, Donald L. D. Caspar

“…Crystallographic analysis at 2-Å resolution of the selective binding of dihalogenated methane, ethane, and ethylene compounds in the cavity on the cubic…”
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Monovalent cation binding to cubic insulin crystals by Gursky, O., Li, Y., Badger, J., Caspar, D.L.

“…Two localized monovalent cation binding sites have been identified in cubic insulin from 2.8 A-resolution difference electron density maps comparing crystals…”
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Structure and selectivity of a monovalent cation binding site in cubic insulin crystals by Badger, J., Kapulsky, A., Gursky, O., Bhyravbhatla, B., Caspar, D.L.

“…Cubic insulin crystals contain a binding site for monovalent cations in a cavity of the crystal dyad in which the bound cation is ligated by protein atomic…”
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Human Plasma High-density Lipoproteins are Stabilized by Kinetic Factors by Mehta, Ranjana, Gantz, Donald L., Gursky, Olga

“…High-density lipoproteins (HDL) are heterogeneous complexes of proteins and lipids that mediate cholesterol removal from the body. Our thermal and chemical…”
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Effects of Salt on the Thermal Stability of Human Plasma High-Density Lipoprotein by Jayaraman, Shobini, Gantz, Donald L, Gursky, Olga

“…High-density lipoproteins (HDL) mediate cholesterol removal and thereby protect against atherosclerosis. Mature spherical HDL contain the apolar lipid core and…”
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Kinetic Stabilization and Fusion of Apolipoprotein A-2:DMPC Disks: Comparison with apoA-1 and apoC-1 by Jayaraman, Shobini, Gantz, Donald L., Gursky, Olga

“…Denaturation studies of high-density lipoproteins (HDL) containing human apolipoprotein A-2 (apoA-2) and dimyristoyl phosphatidylcholine indicate kinetic…”
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Structural Basis for Thermal Stability of Human Low-Density Lipoprotein by Jayaraman, Shobini, Gantz, Donald, Gursky, Olga

“…The stability of human low-density lipoprotein (LDL), the major cholesterol carrier in plasma, was analyzed by heating samples of different concentrations at a…”
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