Search Results - "Gursky, J"

Petrology and industrial application of main diatomite deposits in the Transuralian region (Russian Federation) by Smirnov, P. V., Konstantinov, A. O., Gursky, H.-J.

“…In the middle of the last centuary, large resources of Paleocene–Eocene diatomites were discovered in the Transuralian region. By now, more than 100…”
Get full text

Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation by Stetka, J., Vyhlidalova, P., Lanikova, L., Koralkova, P., Gursky, J., Hlusi, A., Flodr, P., Hubackova, S., Bartek, J., Hodny, Z., Divoky, V.

“…Inflammatory and oncogenic signaling converge in disease evolution of BCR–ABL-negative myeloproliferative neoplasms, clonal hematopoietic stem cell disorders…”
Get full text

Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress by Chroma, K, Mistrik, M, Moudry, P, Gursky, J, Liptay, M, Strauss, R, Skrott, Z, Vrtel, R, Bartkova, J, Kramara, J, Bartek, J

“…Chromatin DNA damage response (DDR) is orchestrated by the E3 ubiquitin ligase ring finger protein 168 (RNF168), resulting in ubiquitin-dependent recruitment…”
Get full text

The prognostic value of DNA damage level in peripheral blood lymphocytes in germ cell cancer patients by Mego, M., Sestakova, Z., Kalavska, K., Hurbanova, L., Jurkovicova, D., Gursky, J., Chovanec, M., Svetlovska, D., Miskovska, V., Obertova, J., Palacka, P., Rejlekova, K., Sycova-Mila, Z., Mardiak, J., Chovanec, M.

Get full text

An Equation of Monge-Ampère Type in Conformal Geometry, and Four-Manifolds of Positive Ricci Curvature by Chang, Sun-Yung A., Gursky, Matthew J., Yang, Paul C.

“…We formulate natural conformally invariant conditions on a 4-manifold for the existence of a metric whose Schouten tensor satisfies a quadratic inequality…”
Get full text

Conformal Invariants Associated to a Measure by Chang, Sun-Yung A., Gursky, Matthew J., Yang, Paul

“…In this note, we study some conformal invariants of a Riemannian manifold ($M^{n}$, g) equipped with a smooth measure m. In particular, we show that there is a…”
Get full text

Non-existence of Poincaré–Einstein manifolds with prescribed conformal infinity by Gursky, Matthew J., Han, Qing

“…In this note we prove the existence of infinitely many positive conformal classes on S 7 which cannot be the conformal infinity of a Poincaré–Einstein metric…”
Get full text

Index-Energy Estimates for Yang–Mills Connections and Einstein Metrics by Gursky, Matthew J., Kelleher, Casey Lynn, Streets, Jeffrey

“…We prove a conformally invariant estimate for the index of Schrödinger operators acting on vector bundles over four-manifolds, related to the classical…”
Get full text

Transcription factor IIH - the protein complex with multiple functions by Mydlikova, Z, Gursky, J, Pirsel, M

“…Transcription factor IIH (TFIIH) is eukaryotic multi protein complex identified in early 90's. Subsequent years have shown exceptional conservation of its…”
Get more information

The Weyl Functional, de Rham Cohomology, and Kähler-Einstein Metrics by Gursky, Matthew J.

Get full text

A new variational characterization of three-dimensional space forms by Gursky, Matthew J., Viaclovsky, Jeff A.

Get full text

Fully Nonlinear Equations on Riemannian Manifolds with Negative Curvature by Gursky, Matthew J., Viaclovsky, Jeff A.

“…It is proved that every compact Riemannian manifold of dimension n ≥ 3 with negative Ricci curvature is conformal to a metric with det(Ric) = constant. This is…”
Get full text

The effects of antidepressants on sleep: a review by Gursky, J T, Krahn, L E

“…Sleep disturbances are a frequent complication of depressive disorders and their treatment. Familiarity with the interaction among sleep, depression, and…”
Get more information

Convexity and singularities of curvature equations in conformal geometry by Gursky, Matthew J., Viaclovsky, Jeff

“…We define a generalization of convex functions, which we call δ-convex functions, and show that they must satisfy interior Hölder and W1,p estimates. As an…”
Get full text

An a priori estimate for a fully nonlinear equation on four-manifolds by Chang, Sun-Yung A., Gursky, Matthew J., Yang, Paul

Get full text

Prescribing Symmetric Functions of the Eigenvalues of the Ricci Tensor by Gursky, Matthew J., Viaclovsky, Jeff A.

“…We study the problem of conformally deforming a metric to a prescribed symmetric function of the eigenvalues of the Ricci tensor. We prove an existence theorem…”
Get full text

Disulfiram’s anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase by Skrott, Zdenek, Majera, Dusana, Gursky, Jan, Buchtova, Tereza, Hajduch, Marian, Mistrik, Martin, Bartek, Jiri

“…Aldehyde dehydrogenase (ALDH) is a proposed biomarker and possible target to eradicate cancer stem cells. ALDH inhibition as a treatment approach is supported…”
Get full text

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 by Skrott, Zdenek, Mistrik, Martin, Andersen, Klaus Kaae, Friis, Søren, Majera, Dusana, Gursky, Jan, Ozdian, Tomas, Bartkova, Jirina, Turi, Zsofia, Moudry, Pavel, Kraus, Marianne, Michalova, Martina, Vaclavkova, Jana, Dzubak, Petr, Vrobel, Ivo, Pouckova, Pavla, Sedlacek, Jindrich, Miklovicova, Andrea, Kutt, Anne, Li, Jing, Mattova, Jana, Driessen, Christoph, Dou, Q. Ping, Olsen, Jørgen, Hajduch, Marian, Cvek, Boris, Deshaies, Raymond J., Bartek, Jiri

“…Cancer incidence is rising and this global challenge is further exacerbated by tumour resistance to available medicines. A promising approach to meet the need…”
Get full text

In vitro evolution of styrene monooxygenase from Pseudomonas putida CA-3 for improved epoxide synthesis by Gursky, Lucas J, Nikodinovic-Runic, Jasmina, Feenstra, K. Anton, O'Connor, Kevin E

“…The styAB genes from Pseudomonas putida CA-3, which encode styrene monooxygenase, were subjected to three rounds of in vitro evolution using error-prone…”
Get full text

On Einstein Manifolds of Positive Sectional Curvature by Gursky, Matthew J, LeBrun, Claude

“…Let (M, g) be a compact oriented four-dimensional Einstein manifold. If M has positive intersection form and g has non-negative sectional curvature, we show…”
Get full text