Search Results - "Gursky, G V"

Binding of Hoechst 33258 and its Derivatives to DNA by Bazhulina, N. P., Nikitin, A. M., Rodin, S. A., Surovaya, A. N., Kravatsky, Yu. V., Pismensky, V. F., Archipova, V. S., Martin, R., Gursky, G. V.

“…In the present work, we employed UV-VIS spectroscopy, fluorescence methods, and circular dichroism spectroscopy (CD) to study the interaction of dye Hoechst…”
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Targeting Holliday junctions by origin DNA-binding protein of herpes simplex virus type 1 by Moiseeva, E.D., Bazhulina, N.P., Gursky, Y.G., Grokhovsky, S.L., Surovaya, A.N., Gursky, G.V.

“…In the present paper, the interactions of the origin binding protein (OBP) of herpes simplex virus type 1 (HSV1) with synthetic four-way Holliday junctions…”
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Sequence-Specific Minor Groove Binding Ligands as Potential Regulators of Gene Expression in Xenopus Laevis Oocytes by Belikov, S. V., Grokhovsky, S. L., Isaguliants, M. G., Surovaya, A. N., Gursky, G. V.

“…The mouse mammary tumor virus (MMTV) promoter is induced by glucocorticoid hormone. A robust hormone- and receptor-dependent gene activation could be…”
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DNA sequence recognition by bis-linked netropsin and distamycin derivatives by Grokhovsky, S.L, Surovaya, A.N, Burckhardt, G, Pismensky, V.F, Chernov, B.K, Zimmer, Ch, Gursky, G.V

“…We studied the interaction of cis-diammine Pt(II)-bridged bis-netropsin, cis-diammine Pt(II)-bridged bis-distamycin and oligomethylene-bridged bis-netropsin…”
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Complex of the herpes simplex virus type 1 origin binding protein UL9 with DNA as a platform for the design of a new type of antiviral drugs by Bazhulina, N.P., Surovaya, A.N., Gursky, Y.G., Andronova, V.L., Moiseeva, E.D., Nikitin, А.M., Golovkin, M.V., Galegov, G.А., Grokhovsky, S.L., Gursky, G.V.

“…The herpes simplex virus type 1 origin-binding protein, OBP, is a DNA helicase encoded by the UL9 gene. The protein binds in a sequence-specific manner to the…”
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Effect of dimeric netropsin analogue 15Lys-bis-Nt and acyclovir on the reproduction of herpes simplex virus type 1. The search for variants of herpes virus with drug resistance to 15Lys-bis-Nt and acyclovir by Andronova, V. L., Grokhovsky, S. L., Surovaya, A. N., Gursky, G. V., Galegov, G. A.

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Binding of Bis-linked Netropsin Derivatives in the Parallel-Stranded Hairpin Form to DNA by Surovaya, A. N., Burckhardt, G., Grokhovsky, S. L., Birch-Hirschfeld, E., Nikitin, A. M., Fritzsche, H., Zimmer, Ch, Gursky, G. V.

“…Cis-diammine Pt(II)- bridged bis-netropsin and oligomethylene-bridged bis-netropsin in which two monomers are linked in a tail-to-tail manner bind to the DNA…”
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Effect of DNA Local Conformation on the Affinity and Binding Specificity of bis-Netropsins to DNA by Surovaya, A N, Grokhovsky, S L, Burckhardt, G, Fritzsche, H, Zimmer, Ch, Gursky, G V

“…The interaction of short nucleotide duplexes with bis-netropsins, in which netropsin fragments are linked tail-to-tail via cis-diammineplatinum group ([arrow…”
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Design of sequence-specific DNA binding ligands that use a two-stranded peptide motif for DNA sequence recognition by Nikolaev, V A, Grokhovsky, S L, Surovaya, A N, Leinsoo, T A, Sidorova NYu, Zasedatelev, A S, Zhuze, A L, Strahan, G A, Shafer, R H, Gursky, G V

“…The design and DNA binding activity of beta-structure-forming peptides and netropsin-peptide conjugates are reported. It is found that a pair of…”
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Antiviral and cytotoxic activity of netropsin derivatives in vero cells infected with vaccinia virus and herpes simplex virus type I by Andronova, V. L., Grokhovsky, S. L., Surovaya, A. N., Arkhipova, V. S., Gursky, G. V., Galegov, G. A.

“…A study examined the antiviral activity of a series of new netropsin derivatives in Vero E6 cells infected with vaccinia virus and herpes simplex virus type I…”
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Interaction of lambda cro repressor with synthetic operator OR3 studied by competition binding with minor groove binders by Gursky, G V, Surovaya, A N, Kurochkin, A V, Chernov, B K, Volkov, S K, Kirpichnikov, M P

“…In the present work, we employ a combination of CD spectroscopy and gel retardation technique to characterize thermodynamically the binding of lambda phage cro…”
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Cooperative effects on binding of proteins to DNA by Nechipurenko, Y D, Gursky, G V

“…Equations are derived for description of cooperative binding of large ligands to a homogeneous polynucleotide lattice for a wide variety of binding models…”
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New structural motifs isohelical to DNA by Nikitin, A M, Gursky, G V

“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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Triple rings: a new type of compact structure of circular DNA by Vengerov, Y Y, Semenov, T E, Streltsov, S A, Makarov, V L, Khorlin, A A, Gursky, G V

“…Complexes of circular superhelical pBR322 DNA with a synthetic tripeptide capable of beta-structure formation (dansylhydrazide trivaline) were studied at…”
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Torus-shaped particles formed due to intermolecular condensation of circular DNA upon interaction with synthetic tripeptide by Vengerov, Y.Y., Semenov, T.E., Streltsov, S.A., Makarov, V.L., Khorlin, A.A., Gursky, G.V.

“…The morphology of complexes between relaxed circular plasmid pBR322 DNA and tripeptide L-Val-L-Val-L-Val-NH-NH-Dns (TVP) at different peptide/DNA ratios was…”
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The antiviral activity of the combinations of netropsin derivatives with modified nucleosides and phosphonoacetic acid as estimated in the model of herpesvirus type 1 in a vero cell culture by Andronova, V L, Grokhovsky, S L, Surovaya, A N, Gursky, G V, Galegov, G A

“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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Design and synthesis of sequence-specific DNA-binding peptides by Grokhovsky, S L, Surovaya, A N, Brussov, R V, Chernov, B K, Sidorova NYu, Gursky, G V

“…Design, synthesis and DNA binding activities of two peptides containing 32 and 102 residues are reported. A nonlinear 102-residue peptide contains four…”
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Synthetic sequence-specific ligands by Gursky, G V, Zasedatelev, A S, Zhuze, A L, Khorlin, A A, Grokhovsky, S L, Streltsov, S A, Surovaya, A N, Nikitin, S M, Krylov, A S, Retchinsky, V O, Mikhailov, M V, Beabealashvili, R S, Gottikh, B P

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A new pseudopeptide motif for designing specific DNA-binding compounds capable of recognizing long DNA sequences by Nikitin, A M, Rodin, S A, Pis'menskii, V F, Surovaya, A N, Gursky, G V

“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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Mono-, di- and trimeric binding of a bis-netropsin to DNA by Zasedatelev, A.S., Borodulin, V.B., Grokhovsky, S.L., Nikitin, A.M., Salmanova, D.V., Zhuze, A.L., Gursky, G.V., Shafer, R.H.

“…An unusual 3:1 stoichiometry for complex formation between an elongated bis-netropsin compound and its binding site on DNA has been observed. Circular…”
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