Search Results - "Gurski, Lisa A"
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Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells
Published in Biomaterials (01-10-2009)“…Abstract The current investigation aimed to develop a biomimetic, three-dimensional (3D) culture system for poorly adherent bone metastatic prostate cancer…”
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Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids
Published in Biomaterials (01-12-2012)“…Abstract Cancer cells cultured in physiologically relevant, three-dimensional (3D) matrices can recapture many essential features of native tumor tissues. In…”
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Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels
Published in PloS one (16-11-2012)“…To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel…”
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Hyaluronan: A simple polysaccharide with diverse biological functions
Published in Acta biomaterialia (01-04-2014)“…Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and…”
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Fibronectin Matrix Formation is a Prerequisite for Colonization of Kidney Tumor Cells in Fibrin
Published in Journal of Cancer (2015)“…Fibrin plays an important role in lung metastasis. Here we show that fibrin promotes colony formation in primary kidney tumor cells from patients with kidney…”
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Kidney Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology
Published in Journal of the National Comprehensive Cancer Network (01-01-2022)“…The NCCN Guidelines for Kidney Cancer focus on the screening, diagnosis, staging, treatment, and management of renal cell carcinoma (RCC). Patients with…”
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Relocation of CLIC1 promotes tumor cell invasion and colonization of fibrin
Published in Molecular cancer research (01-02-2015)“…Chloride intracellular channel 1 (CLIC1) has been shown to be upregulated in various malignancies but its exact function remains unclear. Here, it is revealed…”
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Bladder Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology
Published in Journal of the National Comprehensive Cancer Network (01-03-2020)“…This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Bladder Cancer focuses on the clinical presentation and workup of…”
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Integrin αvβ3 and Fibronectin Upregulate Slug in Cancer Cells to Promote Clot Invasion and Metastasis
Published in Cancer research (Chicago, Ill.) (15-10-2013)“…The blood clotting cascade is selectively involved in lung metastasis, but the reason for this selectivity is unclear. Here, we show that tumor cells that…”
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Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology
Published in Journal of the National Comprehensive Cancer Network (01-09-2019)“…Small bowel adenocarcinoma (SBA) is a rare malignancy of the gastrointestinal tract that has increased in incidence across recent years. Often diagnosed at an…”
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Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP
Published in RNA (Cambridge) (01-02-2011)“…Unlike ribonucleoprotein complexes that have a highly ordered overall architecture, such as the ribosome, yeast telomerase appears to be much more loosely…”
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Amphiphilic Block Co-polyesters Bearing Pendant Cyclic Ketal Groups as Nanocarriers for Controlled Release of Camptothecin
Published in Journal of biomaterials science. Polymer ed. (01-01-2011)“…Amphiphilic block co-polymers consisting of hydrophilic poly(ethylene glycol) and hydrophobic polyester bearing pendent cyclic ketals were synthesized by…”
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Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
Published in Journal of the National Comprehensive Cancer Network (01-06-2024)“…Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. Management of…”
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NCCN Guidelines® Insights: Bladder Cancer, Version 3.2024
Published in Journal of the National Comprehensive Cancer Network (01-05-2024)“…Bladder cancer, the sixth most common cancer in the United States, is most commonly of the urothelial carcinoma histologic subtype. The clinical spectrum of…”
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NCCN Guidelines® Insights: Kidney Cancer, Version 2.2024
Published in Journal of the National Comprehensive Cancer Network (01-02-2024)“…The NCCN Guidelines for Kidney Cancer provide multidisciplinary recommendations for diagnostic workup, staging, and treatment of patients with renal cell…”
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Hyaluronan
Published in PloS one (16-11-2012)“…To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel…”
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Abstract 3206: Three-dimensional hyaluronan hydrogel culture systems facilitate study of the complex microenvironment of bone metastatic prostate cancer cells
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract The bone marrow microenvironment is a complex milieu, containing various stromal and endothelial cell populations as well as a unique extracellular…”
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Abstract 523: Three-dimensional hyaluronic acid-based hydrogel systems for studies of cancer invasion
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Currently available invasion assays for study of cancer metastasis have limitations that led us to develop a novel system that provides a more…”
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Amphiphilic block copolyesters bearing pendant cyclic ketal groups as nanocarriers for controlled release of camptothecin
Published in Journal of biomaterials science. Polymer ed. (01-03-2011)“…Amphiphilic block copolymers consisting of hydrophilic poly(ethylene glycol) and hydrophobic polyester bearing pendent cyclic ketals were synthesized by…”
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