Search Results - "Gurski, Lisa A"

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    Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells by Gurski, Lisa A, Jha, Amit K, Zhang, Chu, Jia, Xinqiao, Farach-Carson, Mary C

    Published in Biomaterials (01-10-2009)
    “…Abstract The current investigation aimed to develop a biomimetic, three-dimensional (3D) culture system for poorly adherent bone metastatic prostate cancer…”
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    Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids by Xu, Xian, Gurski, Lisa A, Zhang, Chu, Harrington, Daniel A, Farach-Carson, Mary C, Jia, Xinqiao

    Published in Biomaterials (01-12-2012)
    “…Abstract Cancer cells cultured in physiologically relevant, three-dimensional (3D) matrices can recapture many essential features of native tumor tissues. In…”
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    Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels by Gurski, Lisa A, Xu, Xian, Labrada, Lyana N, Nguyen, Ngoc T, Xiao, Longxi, van Golen, Kenneth L, Jia, Xinqiao, Farach-Carson, Mary C

    Published in PloS one (16-11-2012)
    “…To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel…”
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    Hyaluronan: A simple polysaccharide with diverse biological functions by Dicker, Kevin T., Gurski, Lisa A., Pradhan-Bhatt, Swati, Witt, Robert L., Farach-Carson, Mary C., Jia, Xinqiao

    Published in Acta biomaterialia (01-04-2014)
    “…Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and…”
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    Fibronectin Matrix Formation is a Prerequisite for Colonization of Kidney Tumor Cells in Fibrin by Knowles, Lynn M, Gurski, Lisa A, Maranchie, Jodi K, Pilch, Jan

    Published in Journal of Cancer (2015)
    “…Fibrin plays an important role in lung metastasis. Here we show that fibrin promotes colony formation in primary kidney tumor cells from patients with kidney…”
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    Relocation of CLIC1 promotes tumor cell invasion and colonization of fibrin by Gurski, Lisa A, Knowles, Lynn M, Basse, Per H, Maranchie, Jodi K, Watkins, Simon C, Pilch, Jan

    Published in Molecular cancer research (01-02-2015)
    “…Chloride intracellular channel 1 (CLIC1) has been shown to be upregulated in various malignancies but its exact function remains unclear. Here, it is revealed…”
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    Integrin αvβ3 and Fibronectin Upregulate Slug in Cancer Cells to Promote Clot Invasion and Metastasis by KNOWLES, Lynn M, GURSKI, Lisa A, ENGEL, Charlotte, GNARRA, James R, MARANCHIE, Jodi K, PILCH, Jan

    Published in Cancer research (Chicago, Ill.) (15-10-2013)
    “…The blood clotting cascade is selectively involved in lung metastasis, but the reason for this selectivity is unclear. Here, we show that tumor cells that…”
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    Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP by Zappulla, David C, Goodrich, Karen J, Arthur, Julian R, Gurski, Lisa A, Denham, Elizabeth M, Stellwagen, Anne E, Cech, Thomas R

    Published in RNA (Cambridge) (01-02-2011)
    “…Unlike ribonucleoprotein complexes that have a highly ordered overall architecture, such as the ribosome, yeast telomerase appears to be much more loosely…”
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    Amphiphilic Block Co-polyesters Bearing Pendant Cyclic Ketal Groups as Nanocarriers for Controlled Release of Camptothecin by Wang, Xiaoying, Gurski, Lisa A., Zhong, Sheng, Xu, Xian, Pochan, Darrin J., Farach-Carson, Mary C., Jia, Xinqiao

    “…Amphiphilic block co-polymers consisting of hydrophilic poly(ethylene glycol) and hydrophobic polyester bearing pendent cyclic ketals were synthesized by…”
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    Hyaluronan by Gurski, Lisa A, Xu, Xian, Labrada, Lyana N, Nguyen, Ngoc T, Xiao, Longxi, van Golen, Kenneth L, Jia, Xinqiao, Farach-Carson, Mary C

    Published in PloS one (16-11-2012)
    “…To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel…”
    Get full text
    Journal Article
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    Abstract 3206: Three-dimensional hyaluronan hydrogel culture systems facilitate study of the complex microenvironment of bone metastatic prostate cancer cells by Gurski, Lisa A., Fong, Eliza L.S., Milton, Russell L., Xu, Xian, Navone, Nora, Jia, Xinqiao, Harrington, Daniel A., Farach-Carson, Mary C.

    Published in Cancer research (Chicago, Ill.) (15-04-2012)
    “…Abstract The bone marrow microenvironment is a complex milieu, containing various stromal and endothelial cell populations as well as a unique extracellular…”
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    Abstract 523: Three-dimensional hyaluronic acid-based hydrogel systems for studies of cancer invasion by Gurski, Lisa A., Nguyen, Ngoc T., van Golen, Kenneth C., Jia, Xinqiao, Farach-Carson, Mary C.

    Published in Cancer research (Chicago, Ill.) (15-04-2010)
    “…Abstract Currently available invasion assays for study of cancer metastasis have limitations that led us to develop a novel system that provides a more…”
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    Amphiphilic block copolyesters bearing pendant cyclic ketal groups as nanocarriers for controlled release of camptothecin by Wang, Xiaoying, Gurski, Lisa A., Zhong, Sheng, Xu, Xian, Pochan, Darrin J., Farach-Carson, Mary C., Jia, Xinqiao

    “…Amphiphilic block copolymers consisting of hydrophilic poly(ethylene glycol) and hydrophobic polyester bearing pendent cyclic ketals were synthesized by…”
    Get full text
    Journal Article