Search Results - "Gurr, Sarah. J."
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Tackling the emerging threat of antifungal resistance to human health
Published in Nature reviews. Microbiology (01-09-2022)“…Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis…”
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Plant pathogen infection risk tracks global crop yields under climate change
Published in Nature climate change (01-08-2021)“…Global food security is strongly determined by crop production. Climate change-induced losses to production can occur directly or indirectly, including via the…”
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Worldwide emergence of resistance to antifungal drugs challenges human health and food security
Published in Science (American Association for the Advancement of Science) (18-05-2018)“…The recent rate of emergence of pathogenic fungi that are resistant to the limited number of commonly used antifungal agents is unprecedented. The azoles, for…”
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global spread of crop pests and pathogens
Published in Global ecology and biogeography (01-12-2014)“…AIM: To describe the patterns and trends in the spread of crop pests and pathogens around the world, and determine the socioeconomic, environmental and…”
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Against the grain: safeguarding rice from rice blast disease
Published in Trends in biotechnology (Regular ed.) (01-03-2009)“…Rice is the staple diet of more than three billion people. Yields must double over the next 40 years if we are to sustain the nutritional needs of the…”
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Pathogens and insect herbivores drive rainforest plant diversity and composition
Published in Nature (London) (06-02-2014)“…Suppressing fungi in a tropical forest plant community lowers diversity by reducing the negative effects of density on seedling recruitment, and removing…”
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Geometry and evolution of the ecological niche in plant-associated microbes
Published in Nature communications (11-06-2020)“…The ecological niche can be thought of as a volume in multidimensional space, where each dimension describes an abiotic condition or biotic resource required…”
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Emerging fungal threats to animal, plant and ecosystem health
Published in Nature (London) (12-04-2012)“…Pathogenic fungi are increasingly contributing to the global emerging disease burden, threatening biodiversity and imposing increasing costs on ecosystem…”
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Crop pests and pathogens move polewards in a warming world
Published in Nature climate change (01-11-2013)“…The extent to which crop pests and pathogens have altered their latitudinal ranges in response to climate change remains largely unknown. Now observations of…”
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Chitosan Mediates Germling Adhesion in Magnaporthe oryzae and Is Required for Surface Sensing and Germling Morphogenesis
Published in PLoS pathogens (17-06-2016)“…The fungal cell wall not only plays a critical role in maintaining cellular integrity, but also forms the interface between fungi and their environment. The…”
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Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture
Published in mBio (05-05-2020)“…The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with respect to its profound impact on global health, biodiversity,…”
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Threats to global food security from emerging fungal and oomycete crop pathogens
Published in Nature food (01-06-2020)“…Emerging fungal and oomycete pathogens infect staple calorie crops and economically important commodity crops, thereby posing a significant risk to global food…”
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Magnaporthe grisea Cutinase2 Mediates Appressorium Differentiation and Host Penetration and Is Required for Full Virulence
Published in The Plant cell (01-08-2007)“…The rice blast fungus Magnaporthe grisea infects its host by forming a specialized infection structure, the appressorium, on the plant leaf. The enormous…”
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Economic and physical determinants of the global distributions of crop pests and pathogens
Published in The New phytologist (01-05-2014)“…Crop pests and pathogens pose a significant and growing threat to food security, but their geographical distributions are poorly understood. We present a…”
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A lipophilic cation protects crops against fungal pathogens by multiple modes of action
Published in Nature communications (30-03-2020)“…The emerging resistance of crop pathogens to fungicides poses a challenge to food security and compels discovery of new antifungal compounds. Here, we show…”
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Zymoseptoria tritici white-collar complex integrates light, temperature and plant cues to initiate dimorphism and pathogenesis
Published in Nature communications (26-09-2022)“…Transitioning from spores to hyphae is pivotal to host invasion by the plant pathogenic fungus Zymoseptoria tritici . This dimorphic switch can be initiated by…”
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NOXious gases and the unpredictability of emerging plant pathogens under climate change
Published in BMC biology (08-05-2017)“…Emerging pathogens of crops threaten food security and are increasingly problematic due to intensive agriculture and high volumes of trade and transport in…”
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Robust anti-oxidant defences in the rice blast fungus Magnaporthe oryzae confer tolerance to the host oxidative burst
Published in The New phytologist (01-01-2014)“…Plants respond to pathogen attack via a rapid burst of reactive oxygen species (ROS). However, ROS are also produced by fungal metabolism and are required for…”
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Validation of Reference Genes for Robust qRT-PCR Gene Expression Analysis in the Rice Blast Fungus Magnaporthe oryzae
Published in PloS one (25-08-2016)“…The rice blast fungus causes significant annual harvest losses. It also serves as a genetically-tractable model to study fungal ingress. Whilst pathogenicity…”
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Fungi, fungicide discovery and global food security
Published in Fungal genetics and biology (01-11-2020)“…•Fungi pose the greatest biotic challenge to global food security.•Monocultures are ideal fungal pathogen feeding and breeding grounds.•Single target site…”
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