Search Results - "Guroff, J J"
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A High-Density Genome Scan Detects Evidence for a Bipolar-Disorder Susceptibility Locus on 13q32 and Other Potential Loci on 1q32 and 18p11.2
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-1999)“…Bipolar disorder is a severe mental illness characterized by mood swings of elation and depression. Family, twin, and adoption studies suggest a complex…”
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Suggestive Evidence for a Schizophrenia Susceptibility Locus on Chromosome 6q and a Confirmation in an Independent Series of Pedigrees
Published in Genomics (San Diego, Calif.) (01-07-1997)“…We have investigated whether there is a locus on chromosome 6 that confers an increased susceptibility to schizophrenia using a two-stage approach and…”
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The clinical phenomenology of multiple personality disorder: review of 100 recent cases
Published in The journal of clinical psychiatry (01-06-1986)“…The clinical syndrome of multiple personality disorder (MPD) is an unusual dissociative condition that has been poorly characterized. In an attempt to better…”
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Fine mapping supports previous linkage evidence for a bipolar disorder susceptibility locus on 13q32
Published in American journal of medical genetics (08-05-2001)“…A region between D13S71 and D13S274 on 13q32 showed linkage to bipolar disorder (BP) based on a genome scan using markers with an average spacing of ∼6 cM and…”
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Initial genome scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 1, 6, 8, 10, and 12
Published in American journal of medical genetics (31-05-1997)“…A report on an initial genome screen on 540 individuals in 97 families was collected as part of the NIMH Genetics Initiative on Bipolar Disorder. Families were…”
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Initial Genome Scan of the NIMH Genetics Initiative Bipolar Pedigrees: Chromosomes 4, 7, 9, 18, 19, 20, and 21q
Published in American journal of medical genetics (31-05-1997)“…An initial genome scan was performed on 540 individuals from 97 families segregating bipolar disorder, collected through the National Institutes of Mental…”
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Psychiatric disorders in the first-degree relatives of probands with bulimia nervosa
Published in The American journal of psychiatry (01-11-1989)“…Data from a family study of psychiatric disorders showed higher rates of major affective disorders, eating disorders, and alcoholism in first-degree relatives…”
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Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees
Published in American journal of medical genetics (07-02-2000)“…As part of a four‐center NIMH Genetics Initiative on Bipolar Disorder, a genome screen using 365 markers was performed on 540 DNAs from 97 families, enriched…”
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Rates of Obsessive Compulsive Disorder in first degree relatives of patients with trichotillomania: a research note
Published in Journal of child psychology and psychiatry (01-07-1992)“…To explore a possible relationship between trichotillomania, (TTM) (compulsive hair pulling) and Obsessive Compulsive Disorder (OCD), 65 out of 69 (94%) first…”
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A family study of rapid-cycling bipolar illness
Published in Journal of affective disorders (01-07-1988)“…Twenty-nine out of 195 bipolar/episodic schizoaffective patients were judged to be rapid-cyclers (15%). Twenty-five of the 29 were female (86%). The…”
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Validation of criteria for major depression through controlled family study
Published in Journal of affective disorders (01-09-1986)“…As compared with depressed relatives of normals, depressed relatives of affective patients are more likely to have severe impairment or incapacitation in their…”
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A systematic search for a bipolar predisposing locus on chromosome 5
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-1992)“…Chromosome 5 markers spanning the pter to the qter were used to examine linkage to bipolar illness in 14 pedigrees. Twenty-four loci were examined in 237…”
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Intravenous GABA administration is anxiogenic in man
Published in Psychiatry research (01-10-1986)“…Seven persons (three normal volunteers and four euthymic bipolar patients) received one to four doses of gamma-aminobutyric acid (GABA) intravenously. All…”
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A linkage study of bipolar illness
Published in Archives of general psychiatry (01-01-1997)“…Although genetic epidemiological studies of bipolar (BP) illness are consistent with a heritable component, inherited risk factors remain unknown. The goal of…”
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A controlled family study of chronic psychoses. Schizophrenia and schizoaffective disorder
Published in Archives of general psychiatry (01-04-1988)“…Two hundred thirty-seven relatives of 48 patients with chronic psychosis, diagnosed as either schizophrenia or schizoaffective disorder, along with 380…”
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Description of the National Institute of Mental Health family study of affective disorders
Published in Genetic epidemiology (1989)“…The NIMH family study consisted of 172 probands with affective disorder and 43 normal control probands. Psychiatric disorders were diagnosed in relatives over…”
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Behavioral, biochemical and neuroendocrine responses to amphetamine in normal twins and 'well-state' bipolar patients
Published in Psychoneuroendocrinology (1982)“…An i.v. injection of dextroamphetamine (0.3 mgm/kg) was given to 13 pairs of normal monozygotic twins, three pairs of normal dizygotic twins and 11 patients…”
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Birth-cohort changes in manic and depressive disorders in relatives of bipolar and schizoaffective patients
Published in Archives of general psychiatry (01-04-1987)“…Eight hundred twenty-three relatives of bipolar and schizoaffective patients were divided into groups of birth cohorts. The rates of bipolar, schizoaffective,…”
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Information from relatives. Diagnosis of affective disorders
Published in Archives of general psychiatry (01-02-1984)“…We compared diagnoses made blindly by experienced clinicians from interview records with diagnoses obtained by computer pooling and scoring of relatives'…”
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Unipolar relatives in bipolar pedigrees: A search for elusive indicators of underlying bipolarity
Published in American journal of medical genetics (20-09-1996)“…In an effort to identify features indicative of underlying bipolarity within the unipolar relatives of bipolar probands, we compared unipolar relatives of…”
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