Search Results - "Gurney, Travis"

Phytochemical antioxidants modulate mammalian cellular epigenome: implications in health and disease by Malireddy, Smitha, Kotha, Sainath R, Secor, Jordan D, Gurney, Travis O, Abbott, Jamie L, Maulik, Gautam, Maddipati, Krishna R, Parinandi, Narasimham L

“…In living systems, the mechanisms of inheritance involving gene expression are operated by (i) the traditional model of genetics where the deoxyribonucleic…”
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Mixing and oxygen transfer characteristics of a microplate bioreactor with surface‐attached microposts by Fisher, Justin T., Gurney, Travis O., Mason, Brittany M., Fisher, Jay K., Kelly, William J.

“…Bioprocess optimization for cell‐based therapies is a resource heavy activity. To reduce the associated cost and time, process development may be carried out…”
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The Mitochondrial Cardiolipin Remodeling Enzyme Lysocardiolipin Acyltransferase Is a Novel Target in Pulmonary Fibrosis by LONG SHUANG HUANG, MATHEW, Biji, KAMINSKI, Naftali, TONG ZHOU, WEI ZHANG, YANMIN ZHANG, REHMAN, Jalees, KOTHA, Sainath R, GURNEY, Travis O, PARINANDI, Narasimham L, LUSSIER, Yves A, GARCIA, Joe G. N, HAIQUAN LI, NATARAJAN, Viswanathan, YUTONG ZHAO, MA, Shwu-Fan, NOTH, Imre, REDDY, Sekhar P, HARIJITH, Anantha, USATYUK, Peter V, BERDYSHEV, Evgeny V

“…Lysocardiolipin acyltransferase (LYCAT), a cardiolipin-remodeling enzyme regulating the 18:2 linoleic acid pattern of mammalian mitochondrial cardiolipin, is…”
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Adiponectin Protects Against Hyperoxic Lung Injury and Vascular Leak by Sliman, Sean M., Patel, Rishi B., Cruff, Jason P., Kotha, Sainath R., Newland, Christie A., Schrader, Carrie A., Sherwani, Shariq I., Gurney, Travis O., Magalang, Ulysses J., Parinandi, Narasimham L.

“…Adiponectin (Ad), an adipokine exclusively secreted by the adipose tissue, has emerged as a paracrine metabolic regulator as well as a protectant against…”
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Choice of cyclodextrin for cellular cholesterol depletion for vascular endothelial cell lipid raft studies: cell membrane alterations, cytoskeletal reorganization and cytotoxicity by Hinzey, Adam H, Kline, Michelle A, Kotha, Sainath R, Sliman, Sean M, Butler, Elizabeth S O'Connor, Shelton, Andrew B, Gurney, Travis R, Parinandi, Narasimham L

“…The use of cyclodextrins as tools to establish the role of cholesterol rafts in cellular functions has become a widely accepted procedure. However, the adverse…”
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Pulmonary Fibrosis Inducer, Bleomycin, Causes Redox-Sensitive Activation of Phospholipase D and Cytotoxicity Through Formation of Bioactive Lipid Signal Mediator, Phosphatidic Acid, in Lung Microvascular Endothelial Cells by Patel, Rishi B., Kotha, Sainath R., Sherwani, Shariq I., Sliman, Sean M., Gurney, Travis O., Loar, Brooke, Butler, Susan O’Connor, Morris, Andrew J., Marsh, Clay B., Parinandi, Narasimham L.

“…The mechanisms of lung microvascular complications and pulmonary hypertension known to be associated with idiopathic pulmonary fibrosis (IPF), a debilitating…”
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Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-l-cysteine, and novel thiol antioxidant, N,N′-bis-2-mercaptoethyl isophthalamide by Patel, Rishi B., Kotha, Sainath R., Sauers, Lynn A., Malireddy, Smitha, Gurney, Travis O., Gupta, Niladri N., Elton, Terry S., Magalang, Ulysses J., Marsh, Clay B., Haley, Boyd E., Parinandi, Narasimham L.

“…Lung vascular alterations and pulmonary hypertension associated with oxidative stress have been reported to be involved in idiopathic lung fibrosis (ILF)…”
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Novel Lipid-Soluble Thiol-Redox Antioxidant and Heavy Metal Chelator, N,N′-bis(2-Mercaptoethyl)Isophthalamide (NBMI) and Phospholipase D-Specific Inhibitor, 5-Fluoro-2-Indolyl Des-Chlorohalopemide (FIPI) Attenuate Mercury-Induced Lipid Signaling Leading to Protection Against Cytotoxicity in Aortic Endothelial Cells by Secor, Jordan D., Kotha, Sainath R., Gurney, Travis O., Patel, Rishi B., Kefauver, Nicholas R., Gupta, Niladri, Morris, Andrew J., Haley, Boyd E., Parinandi, Narasimham L.

“…Here, we investigated thiol-redox-mediated phospholipase D (PLD) signaling as a mechanism of mercury cytotoxicity in mouse aortic endothelial cell (MAEC) in…”
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Pentalinonsterol exhibits the immunomodulatory action in macrophages through activation of Phospholipase A 2 by Varikuti, Sanjay, Shelton, Blake, Kotha, Sainath R., Gurney, Travis, Gupta, Guarav, Fuchs, James R., Kinghorn, Dougles, Srivastava, Nidhi, Satoskar, Abhay R., Parinandi, Narasimham L.

“…Abstract only…”
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Autoantibodies targeting TRIM72 compromise membrane repair and contribute to inflammatory myopathy by McElhanon, Kevin E, Young, Nicholas, Hampton, Jeffrey, Paleo, Brian J, Kwiatkowski, Thomas A, Beck, Eric X, Capati, Ana, Jablonski, Kyle, Gurney, Travis, Perez, Miguel A Lopez, Aggarwal, Rohit, Oddis, Chester V, Jarjour, Wael N, Weisleder, Noah

“…Idiopathic inflammatory myopathies (IIM) involve chronic inflammation of skeletal muscle and subsequent muscle degeneration due to an uncontrolled autoimmune…”
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Pentalinonsterol, a Phytosterol from Pentalinon andrieuxii, is Immunomodulatory through Phospholipase A2 in Macrophages toward its Antileishmanial Action by Varikuti, Sanjay, Shelton, Andrew B., Kotha, Sainath R., Gurney, Travis, Gupta, Gaurav, Hund, Thomas J., Fuchs, James R., Kinghorn, A. Douglas, Srivastava, Nidhi, Satoskar, Abhay R., Parinandi, Narasimham L.

“…Our earlier in vitro and in vivo studies have revealed that the phytosterol, pentalinonsterol (cholest-4,20,24-trien-3-one) (PEN), isolated from the roots of…”
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Pentalinonsterol, a Phytosterol from Pentalinon andrieuxii, is Immunomodulatory through Phospholipase A 2 in Macrophages toward its Antileishmanial Action by Varikuti, Sanjay, Shelton, Andrew B, Kotha, Sainath R, Gurney, Travis, Gupta, Gaurav, Hund, Thomas J, Fuchs, James R, Kinghorn, A Douglas, Srivastava, Nidhi, Satoskar, Abhay R, Parinandi, Narasimham L

“…Our earlier in vitro and in vivo studies have revealed that the phytosterol, pentalinonsterol (cholest-4,20,24-trien-3-one) (PEN), isolated from the roots of…”
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PSS57 - Oxidized Lipids and Eicosanoids Are Biomarkers of Inflammation in Sickle Cell Disease by Kotha, Sainath, Witkoff, Leslie, Rao, Hemalatha, Gurney, Travis, Desai, Payal, Rao Maddipati, Krishna, Kraut, Eric, Parinandi, Narasimham

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Oxidized Lipids and Eicosanoids Are Biomarkers of Inflammation in Sickle Cell Disease by Kotha, Sainath, Witkoff, Leslie, Rao, Hemalatha, Gurney, Travis, Desai, Payal, Rao Maddipati, Krishna, Kraut, Eric, Parinandi, Narasimham

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Polyunsaturated Fatty Acids Suppress Adiponectin Secretion by Adipocytes: Involvement of Lipid Peroxidation by Kotha, Sainath R, Abbott, Jamie L, Gurney, Travis O, Sherwani, Shariq I, Manalang, Ulysses J, Parinandi, Narasimham L

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Hyperglycemic Carbonyl Stress in Vascular Endothelial Cells and Protection by Heavy Metal Chelators by Gurney, Travis Owen, Sliman, Sean, Patel, Rishi, Kotha, Sainath, Parinandi, Narasimham

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Pulmonary Oxygen Toxicity Protection by Adiponectin by Kotha, Sainath R, Sliman, Sean M, Patel, Rishi B, Cruff, Jason P, Sherwani, Shariq I, Gurney, Travis O, Magalang, Ulysses J, Parinandi, Narasimham L

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