Search Results - "Guri, Yakir"

Structural basis for regulation of human acetyl-CoA carboxylase by Hunkeler, Moritz, Hagmann, Anna, Stuttfeld, Edward, Chami, Mohamed, Guri, Yakir, Stahlberg, Henning, Maier, Timm

“…Acetyl-CoA carboxylase catalyses the ATP-dependent carboxylation of acetyl-CoA, a rate-limiting step in fatty acid biosynthesis 1 , 2 . Eukaryotic acetyl-CoA…”
Get full text

mTOR at the Transmitting and Receiving Ends in Tumor Immunity by Guri, Yakir, Nordmann, Thierry M, Roszik, Jason

“…Cancer is a complex disease and a leading cause of death worldwide. Immunity is critical for cancer control. Cancer cells exhibit high mutational rates and…”
Get full text

mTOR Signaling Confers Resistance to Targeted Cancer Drugs by Guri, Yakir, Hall, Michael N

“…Cancer is a complex disease and a leading cause of death worldwide. Extensive research over decades has led to the development of therapies that target…”
Get more information

Multiplexed on-yeast serological assay for immune escape screening of SARS-CoV-2 variants by Lopez-Morales, Joanan, Vanella, Rosario, Utzinger, Tamara, Schittny, Valentin, Hirsiger, Julia, Osthoff, Michael, Berger, Christoph T., Guri, Yakir, Nash, Michael A.

“…The emergence of the SARS-CoV-2 Omicron variant altered patient risk profiles and shifted the trajectory of the COVID-19 pandemic. Therefore, sensitive…”
Get full text

Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development by Ataca, Dalya, Caikovski, Marian, Piersigilli, Alessandra, Moulin, Alexandre, Benarafa, Charaf, Earp, Sarah E, Guri, Yakir, Kostic, Corinne, Arsenijevic, Yvan, Soininen, Raija, Apte, Suneel S, Brisken, Cathrin

“…The ADAMTS family comprises 19 secreted metalloproteinases that cleave extracellular matrix components and have diverse functions in numerous disease and…”
Get full text

Exacerbation of familial intrahepatic cholestasis in conjunction with COVID-19 vaccination by Guri, Yakir, Vosbeck, Jürg, Dickenmann, Michael, Jetter, Alexander, Bernsmeier, Christine

Get full text

The protein histidine phosphatase LHPP is a tumour suppressor by Hindupur, Sravanth K., Colombi, Marco, Fuhs, Stephen R., Matter, Matthias S., Guri, Yakir, Adam, Kevin, Cornu, Marion, Piscuoglio, Salvatore, Ng, Charlotte K. Y., Betz, Charles, Liko, Dritan, Quagliata, Luca, Moes, Suzette, Jenoe, Paul, Terracciano, Luigi M., Heim, Markus H., Hunter, Tony, Hall, Michael N.

“…Decreased expression of histidine phosphatase LHPP, a novel tumour suppressor, results in increased global histidine phosphorylation and hepatocellular…”
Get full text

mTORC2 Promotes Tumorigenesis via Lipid Synthesis by Guri, Yakir, Colombi, Marco, Dazert, Eva, Hindupur, Sravanth K., Roszik, Jason, Moes, Suzette, Jenoe, Paul, Heim, Markus H., Riezman, Isabelle, Riezman, Howard, Hall, Michael N.

“…Dysregulated mammalian target of rapamycin (mTOR) promotes cancer, but underlying mechanisms are poorly understood. We describe an mTOR-driven mouse model that…”
Get full text

T‐cell synapse formation depends on antigen recognition but not CD3 interaction: Studies with TCR:ζ, a candidate transgene for TCR gene therapy by Roszik, János, Sebestyén, Zsolt, Govers, Coen, Guri, Yakir, Szöőr, Árpád, Pályi‐Krekk, Zsuzsanna, Vereb, György, Nagy, Peter, Szöllősi, János, Debets, Reno

“…T‐cell receptors (TCRs) can be genetically modified to improve gene‐engineered T‐cell responses, a strategy considered critical for the success of clinical TCR…”
Get full text

Cover Picture: Eur. J. Immunol. 5/11 by Roszik, János, Sebestyén, Zsolt, Govers, Coen, Guri, Yakir, Szöőr, Árpád, Pályi‐Krekk, Zsuzsanna, Vereb, György, Nagy, Peter, Szöllősi, János, Debets, Reno

“…The cover image of this issue consists of a confocal microscopic FRET image showing immunological synapse formation in Jurkat T cells, and is taken from Roszik…”
Get full text

T-cell synapse formation depends on antigen recognition but not CD3 interaction: Studies with TCR:[zeta], a candidate transgene for TCR gene therapy by Roszik, János, Sebestyen, Zsolt, Govers, Coen, Guri, Yakir, Szor, Árpád, Palyi-Krekk, Zsuzsanna, Vereb, György, Nagy, Peter, Szollsi, János, Debets, Reno

“…T-cell receptors (TCRs) can be genetically modified to improve gene-engineered T-cell responses, a strategy considered critical for the success of clinical TCR…”
Get full text