Search Results - "Gurgel Rocha, Clarissa Araujo"

Bortezomib suppresses acute myelogenous leukaemia stem‐like KG‐1a cells via NF‐κB inhibition and the induction of oxidative stress by Costa, Rafaela G. A., Oliveira, Maiara de S., Rodrigues, Ana Carolina B. da C., Silva, Suellen L. R., Dias, Ingrid R. S. B., Soares, Milena B. P., Faro Valverde, Ludmila, Gurgel Rocha, Clarissa Araujo, Dias, Rosane Borges, Bezerra, Daniel P.

“…Acute myelogenous leukaemia (AML) originates and is maintained by leukaemic stem cells (LSCs) that are inherently resistant to antiproliferative therapies,…”
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Do laser and led phototherapies influence mast cells and myofibroblasts to produce collagen? by De Castro, Isabele Cardoso Vieira, Rocha, Clarissa Araújo Gurgel, Gomes Henriques, Águida Cristina, Cavalcanti de Sousa, Ana Paula, Lisboa, Márcio Vieira, Sotero, Drielli da Rocha, Pinheiro, Antônio Luiz Barbosa, Cury, Patrícia Ramos, Santos, Jean Nunes dos

“…Laser and LED phototherapies accelerate tissue repair. Mast cells induce the proliferation of fibroblasts and the development of local fibrosis. Increased…”
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In silico approaches for drug repurposing in oncology: a scoping review by Cavalcante, Bruno Raphael Ribeiro, Freitas, Raíza Dias, Siquara da Rocha, Leonardo de Oliveira, Santos, Roberto de Souza Batista Dos, Souza, Bruno Solano de Freitas, Ramos, Pablo Ivan Pereira, Rocha, Gisele Vieira, Gurgel Rocha, Clarissa Araújo

“…Cancer refers to a group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. Due to its complexity, it has been hard…”
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Rapid Detection of SARS-CoV-2 Based on the LAMP Assay Associated with the CRISPRCas12a System by de Sousa, Karoline Almeida Felix, Nonaka, Carolina Kymie Vasques, Khouri, Ricardo, Gurgel Rocha, Clarissa Araújo, Regis-Silva, Carlos Gustavo, de Freitas Souza, Bruno Solano

“…The global public health system has been severely tested by the COVID-19 pandemic. Mass testing was essential in controlling the transmission of the…”
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Cell-in-Cell Events in Oral Squamous Cell Carcinoma by Siquara da Rocha, Leonardo de Oliveira, Souza, Bruno Solano de Freitas, Lambert, Daniel W., Gurgel Rocha, Clarissa de Araújo

“…For over a century, cells within other cells have been detected by pathologists as common histopathological findings in tumors, being generally identified as…”
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The Impact of Histopathological Features on the Prognosis of Oral Squamous Cell Carcinoma: A Comprehensive Review and Meta-Analysis by Dolens, Eder da Silva, Dourado, Mauricio Rocha, Almangush, Alhadi, Salo, Tuula A, Gurgel Rocha, Clarissa Araujo, da Silva, Sabrina Daniela, Brennan, Peter A, Coletta, Ricardo D

“…Over many decades, studies on histopathological features have not only presented high-level evidence of contribution for treatment directions and prognosis of…”
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GMP-compliant extracellular vesicles derived from umbilical cord mesenchymal stromal cells: manufacturing and pre-clinical evaluation in ARDS treatment by Costa-Ferro, Zaquer Suzana Munhoz, Rocha, Gisele Vieira, da Silva, Katia Nunes, Paredes, Bruno Diaz, Loiola, Erick Correia, Silva, Johnatas Dutra, Santos, John Lenon de Souza, Dias, Rosane Borges, Figueira, Cláudio Pereira, de Oliveira, Camila Indiani, de Moura, Ludmilla David, Ribeiro, Lígia Nunes de Morais, de Paula, Eneida, Zanette, Dalila Lucíola, Rocha, Clarissa Araújo Gurgel, Rocco, Patricia Rieken Macedo, Souza, Bruno Solano de Freitas

“…Extracellular vesicles (EVs) represent a new axis of intercellular communication that can be harnessed for therapeutic purposes, as cell-free therapies. The…”
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SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, Northeast Brazil, February 2021 by Nonaka, Carolina Kymie Vasques, Gräf, Tiago, Barcia, Camila Araújo de Lorenzo, Costa, Vanessa Ferreira, de Oliveira, Janderson Lopes, Passos, Rogério da Hora, Bastos, Iasmin Nogueira, de Santana, Maria Clara Brito, Santos, Ian Marinho, de Sousa, Karoline Almeida Felix, Weber, Thamires Gomes Lopes, Siqueira, Isadora Cristina de, Rocha, Clarissa Araújo Gurgel, Mendes, Ana Verena Almeida, Souza, Bruno Solano de Freitas

“…•A second COVID-19 wave accelerated after the emergence of the P.1 lineage (Gamma).•An increased percentage of younger patients needed intensive care during…”
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Exploring the combination of tumor‐stroma ratio, tumor‐infiltrating lymphocytes, and tumor budding with WHO histopathological grading on early‐stage oral squamous cell carcinoma prognosis by Silva, Gabriela Vivili Domingues, Silva Dolens, Eder, Paranaíba, Lívia Máris Ribeiro, Ayroza, Ana Lúcia Carrinho, Gurgel Rocha, Clarissa Araujo, Almangush, Alhadi, Salo, Tuula, Brennan, Peter A., Coletta, Ricardo D.

“…Background While the relevance of the World Health Organization histopathological grading system as a prognostic tool for oral squamous cell carcinoma has…”
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Effects of IGF-1 on Proliferation, Angiogenesis, Tumor Stem Cell Populations and Activation of AKT and Hedgehog Pathways in Oral Squamous Cell Carcinoma by Ferreira Mendes, Jéssica Mariane, de Faro Valverde, Ludmila, Torres Andion Vidal, Manuela, Paredes, Bruno Diaz, Coelho, Paulo, Allahdadi, Kyan James, Coletta, Ricardo Della, Souza, Bruno Solano de Freitas, Rocha, Clarissa Araújo Gurgel

“…(1) Background: Activation of the PI3K-AKT pathway controls most hallmarks of cancer, and the hedgehog (HH) pathway has been associated with oral squamous cell…”
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Overexpression of heat‐shock protein 47 impacts survival of patients with oral squamous cell carcinoma by Costa, Bruno Cesar, Dourado, Mauricio Rocha, Moraes, Everton Freitas, Panini, Luana Marí, Elseragy, Amr, Téo, Fábio Haach, Guimarães, Gustavo Narvaes, Machado, Renato Assis, Risteli, Maija, Gurgel Rocha, Clarissa Araujo, Paranaíba, Lívia Máris Ribeiro, González‐Arriagada, Wilfredo Alejandro, Silva, Sabrina Daniela, Rangel, Ana Lucia Carrinho Ayroza, Marques, Marcelo Rocha, Salo, Tuula, Coletta, Ricardo D.

“…Background The expression of heat‐shock protein 47 (HSP47) has been linked to collagen synthesis control and implicated in fibrotic disorders, but more recent…”
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Stress induced phosphoprotein 1 overexpression controls proliferation, migration and invasion and is associated with poor survival in oral squamous cell carcinoma by Dourado, Mauricio Rocha, Elseragy, Amr, da Costa, Bruno Cesar, Téo, Fábio Haach, Guimarães, Gustavo Narvaes, Machado, Renato Assis, Risteli, Maija, Wahbi, Wafa, Gurgel Rocha, Clarissa Araujo, Paranaíba, Lívia Máris Ribeiro, González-Arriagada, Wilfredo Alejandro, da Silva, Sabrina Daniela, Rangel, Ana Lucia Carrinho Ayroza, Marques, Marcelo Rocha, Rossa Junior, Carlos, Salo, Tuula, Coletta, Ricardo D

“…Although there have been remarkable achievements in the molecular landscape of oral squamous cell carcinoma (OSCC) in recent years, bringing advances in the…”
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GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells by Bacelar Sacramento de Araújo, Taís, de Oliveira Siquara da Rocha, Leonardo, Torres Andion Vidal, Manuela, Cerqueira Coelho, Paulo Lucas, Galvão Dos Reis, Mitermayer, Solano de Freitas Souza, Bruno, Botelho Pereira Soares, Milena, Almeida Pereira, Thiago, Della Coletta, Ricardo, Pereira Bezerra, Daniel, Borges Dias, Rosane, Araújo Gurgel Rocha, Clarissa

“…Due to its importance in the pathogenesis of oral squamous cell carcinoma (OSCC), the Hedgehog (HH) pathway is considered a potential therapeutic target. We…”
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Modeling Autism Spectrum Disorders with Induced Pluripotent Stem Cell-Derived Brain Organoids by Santos, John Lenon de Souza, Araújo, Cecília de Almeida, Rocha, Clarissa Araújo Gurgel, Costa-Ferro, Zaquer Suzana Munhoz, Souza, Bruno Solano de Freitas

“…Autism spectrum disorders (ASD) are a group of complex neurodevelopmental disorders that affect communication and social interactions and present with…”
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Inhibition of CAL27 Oral Squamous Carcinoma Cell by Targeting Hedgehog Pathway With Vismodegib or Itraconazole by Freitas, Raíza Dias, Dias, Rosane Borges, Vidal, Manuela Torres Andion, Valverde, Ludmila de Faro, Gomes Alves Costa, Rafaela, Damasceno, Andresa Karen Andrade, Sales, Caroline Brandi Schlaepfer, Siquara da Rocha, Leonardo de Oliveira, Dos Reis, Mitermayer Galvão, Soares, Milena Botelho Pereira, Coletta, Ricardo Della, Pereira, Thiago Almeida, Bezerra, Daniel Pereira, Gurgel Rocha, Clarissa Araújo

“…Oral Squamous Cell Carcinoma (OSCC) presents an important challenge for the health systems worldwide. Thus, unraveling the biological mechanisms involved in…”
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Assessing the Clinical Impact of the SARS-CoV-2 Gamma Variant on Intensive Care Unit Admissions: Insights from a Reference Hospital in Northeastern Brazil by Nonaka, Carolina Kymie Vasques, de Jesus Ribeiro, Adlas Michel, Rocha, Gisele Vieira, da Hora, Helena Souza, Junior, Antônio Augusto Fonseca, Lima, Fernanda de Macêdo, Bastos, Iasmin Nogueira, Teles, Samara Alves Sa, Weber, Thamires Gomes Lopes, Costa, Vanessa Ferreira, Costa-Ferro, Zaquer Suzana, Rocha, Clarissa Araújo Gurgel, Sardi, Silvia Inês, Soares, Gúbio, Mendes, Ana Verena Almeida, Souza, Bruno Solano de Freitas

“…The global challenge posed by the prolonged COVID-19 pandemic underscores the critical need for ongoing genomic surveillance to identify emerging variants and…”
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Hedgehog pathway activation in oral squamous cell carcinoma: cancer-associated fibroblasts exhibit nuclear GLI-1 localization by Guimaraes, Vanessa Sousa Nazare, Vidal, Manuela Torres Andion, de Faro Valverde, Ludmila, de Oliveira, Marbele Guimarães, de Oliveira Siquara da Rocha, Leonardo, Coelho, Paulo Lucas Cerqueira, Soares, Fernando Augusto, de Freitas Souza, Bruno Solano, Bezerra, Daniel Pereira, Coletta, Ricardo D., Pereira, Thiago Almeida, dos Santos, Jean Nunes, Gurgel Rocha, Clarissa Araújo

“…The purpose of this study was to evaluate the expression of Hedgehog (HH) signaling molecules (SHH and GLI-1) by cancer-associated fibroblasts (CAF) in oral…”
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SARS-CoV-2 Detection via RT-PCR in Matched Saliva and Nasopharyngeal Samples Reveals High Concordance in Different Commercial Assays by de Sousa, Karoline Almeida Felix, Nonaka, Carolina Kymie Vasques, de Ávila Mendonça, Renata Naves, Mascarenhas, Verena Neiva, Weber, Thamires Gomes Lopes, Regis Silva, Carlos Gustavo, Mendes, Ana Verena Almeida, Khouri, Ricardo, Souza, Bruno Solano Freitas, Gurgel Rocha, Clarissa Araújo

“…Self-collected saliva samples can increase the diagnostic efficiency and benefit healthcare workers, patient care, and infection control. This study evaluated…”
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Macrophages and endothelial cells orchestrate tumor-associated angiogenesis in oral cancer via hedgehog pathway activation by Valverde, Ludmila de Faro, Pereira, Thiago de Almeida, Dias, Rosane Borges, Guimarães, Vanessa Sousa Nazaré, Ramos, Eduardo Antônio Gonçalves, Santos, Jean Nunes, Gurgel Rocha, Clarissa Araújo

“…The present study aimed to evaluate the role of Hedgehog (Hh) molecule expression in association with the clinical aspects of oral squamous cell carcinoma…”
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Enhanced Expression of Hedgehog Pathway Proteins in Oral Epithelial Dysplasia by Dias, Rosane Borges, Valverde, Ludmila de Faro, Sales, Caroline Brandi Schlaepfer, Guimarães, Vanessa Sousa Nazaré, Cabral, Márcia Grillo, de Aquino Xavier, Flávia Caló, Dos Santos, Jean Nunes, Ramos, Eduardo Antônio Gonçalves, Gurgel Rocha, Clarissa Araújo

“…The aim of this study was to characterize the profile of the proteins involved in the Hedgehog signaling pathway to aid in the understanding of the…”
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