Search Results - "Gurevich, Maria"

Mechanisms of protein sequence divergence and incompatibility by Wellner, Alon, Raitses Gurevich, Maria, Tawfik, Dan S

“…Alignments of orthologous protein sequences convey a complex picture. Some positions are utterly conserved whilst others have diverged to variable degrees…”
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Overall Survival and Clinical Characteristics of BRCA‐Associated Cholangiocarcinoma: A Multicenter Retrospective Study by Golan, Talia, Raitses‐Gurevich, Maria, Kelley, Robin K., Bocobo, Andrea G., Borgida, Ayelet, Shroff, Rachna T., Holter, Spring, Gallinger, Steven, Ahn, Daniel H., Aderka, Dan, Apurva, Jain, Bekaii‐Saab, Tanois, Friedman, Eitan, Javle, Milind

“…Background Biliary tract malignancies, in particular cholangiocarcinomas (CCA), are rare tumors that carry a poor prognosis. BRCA2 mutation carriers have an…”
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The benefit of pancreatic cancer surveillance in carriers of germline BRCA1/2 pathogenic variants by Laish, Ido, Schechter, Menachem, Dancour, Alain, Lieberman, Sari, Levi, Zohar, Goldberg, Yael, Kedar, Inbal, Hasnis, Erez, Half, Elizabeth, Levi, Gili Reznick, Katz, Lior, Vainer, Elez D., Genzel, Dor, Aharoni, Maya, Chen‐Shtoyerman, Rakefet, Abu‐Freha, Naim, Raitses‐Gurevich, Maria, Golan, Talia, Bernstein‐Molho, Rinat, Ben Yehoyada, Merav, Gluck, Nathan, Rosner, Guy

“…Background Surveillance of high‐risk individuals for pancreatic ductal adenocarcinoma (PDAC) is recommended. This study aimed to determine the prevalence and…”
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Recapitulating the clinical scenario of BRCA‐associated pancreatic cancer in pre‐clinical models by Golan, Talia, Stossel, Chani, Atias, Dikla, Buzhor, Ella, Halperin, Sharon, Cohen, Keren, Raitses‐Gurevich, Maria, Glick, Yulia, Raskin, Stephen, Yehuda, Daniel, Feldman, Anna, Schvimer, Michael, Friedman, Eitan, Karni, Rotem, Wilson, Julie M., Denroche, Robert E., Lungu, Ilinca, Bartlett, John M.S., Mbabaali, Faridah, Gallinger, Steven, Berger, Raanan

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. BRCA‐associated PDAC comprises a clinically relevant subtype. A portion of…”
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Serum matrix metalloproteinase‐7, Syndecan‐1, and CA 19‐9 as a biomarker panel for diagnosis of pancreatic ductal adenocarcinoma by Yablecovitch, Doron, Nadler, Moshe, Ben‐Horin, Shomron, Picard, Orit, Yavzori, Miri, Fudim, Ella, Duchan, Moran Tardio, Sakhnini, Emad, Lang, Alon, Lahav, Maor, Saker, Talia, Neuman, Sandra, Selinger, Limor, Freitz, Biana, Dvir, Revital, Raitses‐Gurevich, Maria, Golan, Talia, Levy, Idan, Laish, Ido

“…Aims and Background Matrix metalloproteinase‐7 (MMP‐7) and Syndecan‐1 (SDC1) are involved in multiple functions during tumorigenesis. We aimed to evaluate the…”
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Construction and characterization of recombinant human C9 or C7 linked to single Chain Fv directed to CD25 by Raitses Gurevich, Maria, Fishelson, Zvi

“…•Cancer cells resist cytotoxicity by the Complement membrane attack complex, MAC.•Complement resistance reduces potency of therapeutic antibodies.•Anti-CD25…”
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Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma by Golan, Talia, O’Kane, Grainne M., Denroche, Robert E., Raitses-Gurevich, Maria, Grant, Robert C., Holter, Spring, Wang, Yifan, Zhang, Amy, Jang, Gun Ho, Stossel, Chani, Atias, Dikla, Halperin, Sharon, Berger, Raanan, Glick, Yulia, Park, J. Patrick, Cuggia, Adeline, Williamson, Laura, Wong, Hui-Li, Schaeffer, David F., Renouf, Daniel J., Borgida, Ayelet, Dodd, Anna, Wilson, Julie M., Fischer, Sandra E., Notta, Faiyaz, Knox, Jennifer J., Zogopoulos, George, Gallinger, Steven

“…Homologous recombination deficiency (HRD) in pancreatic ductal adenocarcinoma (PDAC), remains poorly defined beyond germline (g) alterations in BRCA1, BRCA2,…”
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Serum Syndecan-1: A Novel Biomarker for Pancreatic Ductal Adenocarcinoma by Yablecovitch, Doron, Ben-Horin, Shomron, Picard, Orit, Yavzori, Miri, Fudim, Ella, Nadler, Moshe, Levy, Idan, Sakhnini, Emad, Lang, Alon, Engel, Tal, Lahav, Maor, Saker, Talia, Neuman, Sandra, Selinger, Limor, Dvir, Revital, Raitses-Gurevich, Maria, Golan, Talia, Laish, Ido

“…Syndecan-1 (SDC1) has multiple functions in tumorigenesis in general and specifically in pancreatic cancer. We aimed to evaluate SDC1 as a diagnostic and…”
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The critical incident inventory: characteristics of incidents which affect emergency medical technicians and paramedics by Halpern, Janice, Maunder, Robert G, Schwartz, Brian, Gurevich, Maria

“…Emergency medical technicians (EMTs) and paramedics experience critical incidents which evoke distress and impaired functioning but it is unknown which aspects…”
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Securing sex: Embattled masculinity and the pressured pursuit of women’s bodies in men’s online sex advice by Cosma, Stephanie, Gurevich, Maria

“…This article describes findings from a study examining men’s sex advice centered on cultivating masculinity markers by obtaining sex from multiple women…”
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Patient-derived xenograft models of BRCA-associated pancreatic cancers by Golan, Talia, Atias, Dikla, Stossel, Chani, Raitses-Gurevich, Maria

“…[Display omitted] •Pancreatic cancer patients demonstrate a limited response to chemotherapy.•Pancreatic cancer subtype: unstable tumors co-segregated with…”
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Difference or dysfunction?: Deconstructing desire in the DSM-5 diagnosis of Female Sexual Interest/Arousal Disorder by Thomas, Emily J, Gurevich, Maria

“…This article answers ongoing calls within critical sexuality scholarship to explore how constructions of women’s bodies influence and are influenced by broader…”
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A metabolic switch to the pentose-phosphate pathway induces radiation resistance in pancreatic cancer by Shimoni-Sebag, Ariel, Abramovich, Ifat, Agranovich, Bella, Massri, Rami, Stossel, Chani, Atias, Dikla, Raites-Gurevich, Maria, Yizhak, Keren, Golan, Talia, Gottlieb, Eyal, Lawrence, Yaacov Richard

“…[Display omitted] •Novel model of radioresistance identified in pancreatic cancer.•Radioresistant PDAC cells display metabolic reprogramming.•Elevated…”
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RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer by Jbara, Amina, Lin, Kuan-Ting, Stossel, Chani, Siegfried, Zahava, Shqerat, Haya, Amar-Schwartz, Adi, Elyada, Ela, Mogilevsky, Maxim, Raitses-Gurevich, Maria, Johnson, Jared L., Yaron, Tomer M., Ovadia, Ofek, Jang, Gun Ho, Danan-Gotthold, Miri, Cantley, Lewis C., Levanon, Erez Y., Gallinger, Steven, Krainer, Adrian R., Golan, Talia, Karni, Rotem

“…Pancreatic ductal adenocarcinoma (PDA) is characterized by aggressive local invasion and metastatic spread, leading to high lethality. Although driver gene…”
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Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours by Gavish, Avishai, Tyler, Michael, Greenwald, Alissa C., Hoefflin, Rouven, Simkin, Dor, Tschernichovsky, Roi, Galili Darnell, Noam, Somech, Einav, Barbolin, Chaya, Antman, Tomer, Kovarsky, Daniel, Barrett, Thomas, Gonzalez Castro, L. Nicolas, Halder, Debdatta, Chanoch-Myers, Rony, Laffy, Julie, Mints, Michael, Wider, Adi, Tal, Rotem, Spitzer, Avishay, Hara, Toshiro, Raitses-Gurevich, Maria, Stossel, Chani, Golan, Talia, Tirosh, Amit, Suvà, Mario L., Puram, Sidharth V., Tirosh, Itay

“…Each tumour contains diverse cellular states that underlie intratumour heterogeneity (ITH), a central challenge of cancer therapeutics 1 . Dozens of recent…”
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Strategies for the Management of Patients with Pancreatic Cancer with PARP Inhibitors by Golan, Talia, Raitses-Gurevich, Maria, Beller, Tamar, Carroll, James, Brody, Jonathan R

“…A subset of patients with pancreatic adenocarcinomas (PDAC) harbor mutations that are exploitable in the context of DNA-damage response and repair (DDR)…”
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What makes an incident critical for ambulance workers? Emotional outcomes and implications for intervention by Halpern, Janice, Gurevich, Maria, Schwartz, Brian, Brazeau, Paulette

“…Ambulance workers use the term "critical incident" to refer to a category of workplace stressor. Developing an evidence-based approach to critical incident…”
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Postpartum depression in refugee and asylum-seeking women in Canada: A critical health psychology perspective by Brown-Bowers, Amy, McShane, Kelly, Wilson-Mitchell, Karline, Gurevich, Maria

“…Canada has one of the world's largest refugee resettlement programs in the world. Just over 48 percent of Canadian refugees are women, with many of them of…”
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Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer by Jain, Aditi, Agostini, Lebaron C, McCarthy, Grace A, Chand, Saswati N, Ramirez, AnnJosette, Nevler, Avinoam, Cozzitorto, Joseph, Schultz, Christopher W, Lowder, Cinthya Yabar, Smith, Kate M, Waddell, Ian D, Raitses-Gurevich, Maria, Stossel, Chani, Gorman, Yulia Glick, Atias, Dikla, Yeo, Charles J, Winter, Jordan M, Olive, Kenneth P, Golan, Talia, Pishvaian, Michael J, Ogilvie, Donald, James, Dominic I, Jordan, Allan M, Brody, Jonathan R

“…Patients with metastatic pancreatic ductal adenocarcinoma (PDAC) have an average survival of less than 1 year, underscoring the importance of evaluating novel…”
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AcpM, the Meromycolate Extension Acyl Carrier Protein of Mycobacterium tuberculosis, Is Activated by the 4′-Phosphopantetheinyl Transferase PptT, a Potential Target of the Multistep Mycolic Acid Biosynthesis by Zimhony, Oren, Schwarz, Alon, Raitses-Gurevich, Maria, Peleg, Yoav, Dym, Orly, Albeck, Shira, Burstein, Yigal, Shakked, Zippora

“…Modification of acyl carrier proteins (ACP) or domains by the covalent binding of a 4′-phosphopantetheine (4′-PP) moiety is a fundamental condition for…”
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