Search Results - "Gurdasani, Deepti"
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Genomics of disease risk in globally diverse populations
Published in Nature reviews. Genetics (01-09-2019)“…Risk of disease is multifactorial and can be shaped by socio-economic, demographic, cultural, environmental and genetic factors. Our understanding of the…”
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Delaying the second dose of covid-19 vaccines
Published in BMJ (Online) (18-03-2021)Get more information
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Characteristics and impact of Long Covid: Findings from an online survey
Published in PloS one (08-03-2022)“…Long Covid is a public health concern that needs defining, quantifying, and describing. We aimed to explore the initial and ongoing symptoms of Long Covid…”
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Scientific consensus on the COVID-19 pandemic: we need to act now
Published in The Lancet (British edition) (31-10-2020)“…The infection fatality rate of COVID-19 is several-fold higher than that of seasonal influenza,2 and infection can lead to persisting illness, including in…”
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On the fallibility of simulation models in informing pandemic responses
Published in The Lancet global health (01-06-2020)Get full text
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School reopening without robust COVID-19 mitigation risks accelerating the pandemic
Published in The Lancet (British edition) (27-03-2021)“…While returning to school as soon as possible is imperative for the education, social development, and mental and physical welfare of children, not enough has…”
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Artificial intelligence in public health: the potential of epidemic early warning systems
Published in Journal of International Medical Research (01-03-2023)“…The use of artificial intelligence (AI) to generate automated early warnings in epidemic surveillance by harnessing vast open-source data with minimal human…”
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A general approach for haplotype phasing across the full spectrum of relatedness
Published in PLoS genetics (01-04-2014)“…Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a…”
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Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians
Published in American journal of human genetics (04-06-2015)“…The predominantly African origin of all modern human populations is well established, but the route taken out of Africa is still unclear. Two alternative…”
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Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections
Published in Nature communications (31-07-2020)“…Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish life-long infections and are associated with malignancies. Striking…”
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Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England
Published in BMJ open (08-09-2021)“…ObjectivesTo assess the potential impacts of successive lockdown-easing measures in England, at a point in the COVID-19 pandemic when community transmission…”
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Machine learning to guide the use of adjuvant therapies for breast cancer
Published in Nature machine intelligence (01-08-2021)“…Accurate prediction of the individualized survival benefit of adjuvant therapy is key to making informed therapeutic decisions for patients with early invasive…”
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Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits
Published in Frontiers in genetics (26-04-2019)“…Genome-wide association studies (GWAS) have found hundreds of novel loci associated with full blood count (FBC) phenotypes. However, most of these studies were…”
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An evaluation of HIV elite controller definitions within a large seroconverter cohort collaboration
Published in PloS one (28-01-2014)“…Understanding the mechanisms underlying viral control is highly relevant to vaccine studies and elite control (EC) of HIV infection. Although numerous…”
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Uncertainty around the Long-Term Implications of COVID-19
Published in Pathogens (Basel) (01-10-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 231 million people globally, with more than 4.7 million deaths recorded by…”
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Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations
Published in Scientific reports (21-01-2022)“…Haematological traits are linked to cardiovascular, metabolic, infectious and immune disorders, as well as cancer. Here, we examine the role of genetic…”
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The government wants us to learn to live with covid-19, but where is the learning?
Published in BMJ (Online) (29-04-2022)Get more information
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The parliamentary committee report on covid-19 response
Published in BMJ (Online) (15-10-2021)Get more information
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Herd immunity by infection is not an option
Published in Science (American Association for the Advancement of Science) (15-01-2021)“…Difficult lessons are learned from a largely uncontrolled COVID-19 epidemic in Manaus, Brazil Herd immunity is expected to arise when a virus cannot spread…”
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The NHS is complex, and that's why we should be worried
Published in BMJ (Online) (20-12-2021)Get more information
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