Search Results - "Gurd, FRN"

The Antigenic Structure of Proteins: A Reappraisal by Benjamin, D C, Berzofsky, J A, East, I J, Gurd, F R N, Hannum, C, Leach, S J, Margoliash, E, Michael, J G, Miller, A, Prager, E M, Reichlin, M, Sercarz, E E, Smith-Gill, S J, Todd, P E, Wilson, A C

“…Recent studies from a number of laboratories using monoclonal antibodies directed toward structurally defined protein antigens have produced a large body of…”
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Antigen Conformation Determines Processing Requirements for T-Cell Activation by Streicher, Howard Z., Berkower, Ira J., Busch, Mark, Frank R. N. Gurd, Berzofsky, Jay A.

“…We studied the difference in requirements for processing and presentation to a single T-cell clone of four different forms of the same epitope of sperm whale…”
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John Tileston Edsall: some selected biography and personal reminiscences by Gurd, Frank R.N., Richards, Frederic M.

“…This paper has been written in honor of John T. Edsall. Its purpose is to review briefly the status of science during his active years and the combination of…”
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Calculation of electrostatic interactions in proteins by Matthew, J B, Gurd, F R

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Purification and characterization of phospholamban from canine cardiac sarcoplasmic reticulum by Jones, L R, Simmerman, H K, Wilson, W W, Gurd, F R, Wegener, A D

“…Phospholamban, the putative protein regulator of the Ca2+ pump of cardiac sarcoplasmic reticulum, was purified to apparent homogeneity from canine cardiac…”
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Topographic antigenic determinants recognized by monoclonal antibodies to sperm whale myoglobin by Berzofsky, J A, Buckenmeyer, G K, Hicks, G, Gurd, F R, Feldmann, R J, Minna, J

“…Monoclonal antibodies of high affinity (approximately 10(9) M-1) for sperm whale myoglobin were studied to pinpoint the antigenic determinants with which they…”
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Identification of distinct predominant epitopes recognized by myoglobin- specific T cells under the control of different Ir genes and characterization of representative T cell clones by Berkower, I, Matis, LA, Buckenmeyer, GK, Gurd, FR, Longo, DL, Berzofsky, JA

“…We characterized the fine specificity of antigen recognition of myoglobin-immune T cells from B10.D2, B10.GD, and B10.A(5R) mice. Polyclonal H-2d T cells show…”
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Electrostatic effects in myoglobin. Hydrogen ion equilibria in sperm whale ferrimyoglobin by Shire, S J, Hanania, G I, Gurd, F R

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Stabilization and destabilization of protein structure by charge interactions by Matthew, J B, Gurd, F R

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Comparison of carboxymethlation patterns of harbor seal and sperm whale myoglobins by Nigen, A M, Gurd, FRN

“…Harbor seal (Phoca vitulina) and sperm whale (Physeter catodon) myoglobins were carboxymethylated in 0.2M bromoacetate at pH 6.8. The modification of histidine…”
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A major anti-myoglobin idiotype: influence of H-2-linked Ir genes on idiotype expression by KAWAMURA, H, KOHNO, Y, BUSCH, M, GURD, F. R. N, BERZOFSKY, J. A

“…A rabbit antiidiotypic antiserum raised against an A.SW IgG1K monoclonal anti-sperm whale myoglobin (Mb) antibody, HAL19, and extensively absorbed with normal…”
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Electrostatic interactions in sperm whale myoglobin. Site specificity, roles in structural elements, and external electrostatic potential distributions by Garcia-Moreno, B, Chen, L X, March, K L, Gurd, R S, Gurd, F R

“…The electrostatic free energy contribution to the stability of sperm whale ferrimyoglobin was evaluated according to the static accessibility modified…”
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Rotational motions of side chains of poly-L-lysine by Wittebort, Richard J, Szabo, Attila, Gurd, Frank R. N

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A Possible Immunodominant Epitope Recognized by Murine T Lymphocytes Immune to Different Myoglobins by Berkower, Ira, Buckenmeyer, Gail K., Frank R. N. Gurd, Berzofsky, Jay A.

“…We find that a single region on the surface of different species of myoglobin appears to be immunodominant for T lymphocytes, even though the residues in that…”
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Stepwise Sequence Determination From the Carboxyl Terminus of Peptides by Meuth, J L, Harris, DE, Dwulet, F E, Crowl-Powers, M L, Gurd, FRN

“…The thiocyanate method for stepwise degradation of peptides from their COOH termini has been investigated. The method involves first the reaction of the…”
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Stepwise Sequence Determination From the Carboxyl Terminus of Peptides by Meuth, J L, Harris, DE, Dwulet, F E, Crowl-Powers, M L, Gurd, FRN

“…The thiocyanate method for stepwise degradation of peptides from their COOH termini (Stark, G.R., 1968) has been investigated…”
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Electrostatic contributions to the energetics of dimer-tetramer assembly in human hemoglobin: pH dependence and effect of specifically bound chloride ions by Flanagan, Margaret A, Ackers, Gary K, Matthew, James B, Hanania, George I. H, Gurd, Frank R. N

“…The pH dependence and effects of specifically bound chloride ions on the electrostatic contribution to the energetics of human hemoglobin dimer-tetramer…”
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Analysis of electrostatic interactions and their relationship to conformation and stability of bovine pancreatic trypsin inhibitor by March, Keith L, Maskalick, David G, England, Richard D, Friend, Stephen H, Gurd, Frank R. N

“…The modified Tanford-Kirkwood electrostatic theory has been employed to evaluate pK values for all charge sites in the bovine pancreatic trypsin inhibitor…”
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Contributions of individual amino acid residues to the structural stability of cetacean myoglobins by FLANAGAN, M. A, GARCIA-MORENO E, B, FRIEND, S. H, FELDMANN, R. J, SCOULOUDI, H, GURD, F. R. N

“…The acid-denaturation behavior of eleven cetacean myoglobins has been studied at two ionic strengths, 0.01 and 0.10 M, at 25.0 degrees C. The myoglobulins…”
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Solvent accessibility calculations for sperm whale ferrimyoglobin based on refined crystallographic data by Matthew, J B, Hanania, G I, Gurd, F R

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