Search Results - "Gurazada, Sai Guna Ranjan"
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Massive Analysis of Rice Small RNAs: Mechanistic Implications of Regulated MicroRNAs and Variants for Differential Target RNA Cleavage
Published in The Plant cell (01-12-2011)“…Small RNAs have a variety of important roles in plant development, stress responses, and other processes. They exert their influence by guiding mRNA cleavage,…”
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2
Organizing your space: The potential for integrating spatial transcriptomics and 3D imaging data in plants
Published in Plant physiology (Bethesda) (04-02-2022)“…Plant cells communicate information for the regulation of development and responses to external stresses. A key form of this communication is transcriptional…”
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3
The evolutionary history of small RNAs in Solanaceae
Published in Plant physiology (Bethesda) (01-06-2022)“…The Solanaceae or "nightshade" family is an economically important group with remarkable diversity. To gain a better understanding of how the unique biology of…”
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4
RNA-directed DNA methylation and plant development require an IWR1-type transcription factor
Published in EMBO reports (01-01-2010)“…RNA‐directed DNA methylation (RdDM) in plants requires two RNA polymerase (Pol) II‐related RNA polymerases, namely Pol IV and Pol V. A genetic screen designed…”
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RNA polymerase V-dependent small RNAs in Arabidopsis originate from small, intergenic loci including most SINE repeats
Published in Epigenetics (01-07-2012)“…In plants, heterochromatin is maintained by a small RNA-based gene silencing mechanism known as RNA-directed DNA methylation (RdDM). RdDM requires the…”
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Next-Generation Sequence Databases: RNA and Genomic Informatics Resources for Plants
Published in Plant physiology (Bethesda) (01-01-2020)“…We developed public web sites and resources for data access, display, and analysis of plant small RNAs. These web sites are interconnected with related data…”
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Machine Learning-Driven Multi-Omics for Optimizing Biotherapeutic Production
Published 01-01-2024“…Biotherapeutics, particularly monoclonal antibodies (mAbs) and recombinant adeno-associated viruses (rAAVs), have transformed the treatment landscape for…”
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Dissertation -
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Next-Generation Sequence Databases: RNA and Genomic Informatics Resources for Plants1[OPEN]
Published in Plant physiology (Bethesda) (04-11-2019)“…Tools and approaches for plant small RNA and mRNA data visualization and analysis were developed, taking advantage of numerous sequenced genomes, and…”
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Next-Generation Sequence Databases: RNA and Genomic Informatics Resources for Plants1[OPEN]
Published in Plant physiology (Bethesda) (06-01-2020)“…We developed public web sites and resources for data access, display, and analysis of plant small RNAs. These web sites are interconnected with related data…”
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Journal Article -
10
HEK-Omics: The promise of omics to optimize HEK293 for recombinant adeno-associated virus (rAAV) gene therapy manufacturing
Published 23-08-2024“…Gene therapy is poised to transition from niche to mainstream medicine, with recombinant adeno-associated virus (rAAV) as the vector of choice. However, this…”
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Journal Article