Search Results - "Guray, Tulin"

A pan-cancer transcriptomic study showing tumor specific alterations in central metabolism by Sheraj, Ilir, Guray, N. Tulin, Banerjee, Sreeparna

“…Recently, there has been a resurgence of interest in metabolic rewiring of tumors to identify clinically relevant genes. However, most of these studies have…”
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The potential application of gold-apoferritin nanocages conjugated with 2-amino-2-deoxy-glucose for imaging of breast cancer cells by Aslan, Tuğba Nur, Aşık, Elif, Güray, N. Tülin, Volkan, Mürvet

“…Development of biocompatible and multifunctional nanoprobes for tumor targeting, imaging, and therapy still remains a great challenge. Herein, gold…”
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Cellular uptake and apoptotic potential of rhenium labeled magnetic protein cages in MDA-MB-231 cells by Aşık, Elif, Aslan, Tuğba Nur, Güray, N. Tülin, Volkan, Mürvet

“…[Display omitted] •187Re-magnetoferritin NPs lead significantly higher uptake and cytotoxicity in cancer cells compared to normal cells.•187Re-magnetoferritin…”
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Rapid monitoring of diabetes-induced lipid peroxidation by Fourier transform infrared spectroscopy: Evidence from rat liver microsomal membranes by Severcan, Feride, Gorgulu, Guvenc, Gorgulu, Sevgi Turker, Guray, Tulin

“…Increased oxidative stress is the consequence of either enhanced reactive oxygen species (ROS) production or attenuated ROS scavenging capacity, resulting in…”
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2-Amino-2-deoxy-glucose conjugated cobalt ferrite magnetic nanoparticle (2DG-MNP) as a targeting agent for breast cancer cells by Aşık, Elif, Aslan, Tuğba Nur, Volkan, Mürvet, Güray, N. Tülin

“…Highlights • 2DG labeling led to an increase in selective targeting of MNPs in all breast cells. • 2DG labeled MNPs were internalized efficiently in all breast…”
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Identification of Potential Therapeutic Genes and Pathways in Phytoestrogen Emodin Treated Breast Cancer Cell Lines via Network Biology Approaches by Sakalli-Tecim, Elif, Uyar-Arpaci, Pembegul, Guray, N. Tulin

“…Phytoestrogens have been investigated for their potential anti-tumorigenic effects in various cancers including breast cancer. Emodin being a phytoestrogen…”
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Systems biology based miRNA–mRNA expression pattern analysis of Emodin in breast cancer cell lines by Sakalli-Tecim, Elif, Gur-Dedeoglu, Bala, Guray, N. Tulin

“…Breast cancer has been among the most prominent cancers with high mortality. Currently most of the offered therapeutics are toxic; hence, less toxic…”
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In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration by Tombuloglu, Aysegul, Copoglu, Hulya, Aydin-Son, Yesim, Guray, N. Tulin

“…[Display omitted] •Boric acid led to growth inhibition of HepG2 cells with an estimated IC50 of 24 mM.•Key transcriptional changes accompany the effects of…”
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EF2-kinase targeted cobalt-ferrite siRNA-nanotherapy suppresses BRCA1 -mutated breast cancer by Asik, Elif, Akpinar, Yeliz, Caner, Ayse, Kahraman, Nermin, Guray, Tulin, Volkan, Murvet, Albarracin, Constance, Pataer, Apar, Arun, Banu, Ozpolat, Bulent

“…To investigate the role of EF2K in -mutated breast cancer. We developed silica coated cobalt-ferrite (CoFe) nanoparticles for  delivery of small interfering…”
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Abstract 1125: Eukaryotic Elongation Factor 2 Kinase (eEF-2K) is a novel therapeutic target in BRCA1+ mutated breast cancer by Asik, Elif, Kahraman, Nermin, Guray, Tulin, Volkan, Murvet, Lopez-Berestein, Gabriel, Ozpolat, Bulent

“…Abstract BReast CAncer 1 and 2 (BRCA1/2) tumor suppressor genes are frequently mutated in familial breast and ovarian cancers. Recent clinical trials in breast…”
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Differential expressions and functions of phosphodiesterase enzymes in different regions of the rat heart by Derici, Mehmet Kürşat, Sadi, Gökhan, Cenik, Başar, Güray, Tülin, Demirel-Yilmaz, Emine

“…Phosphodiesterase enzymes (PDEs) are responsible for the adjustment of cyclic nucleotide levels. Alterations in PDE expressions in different tissues cause…”
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Regulation of Glutathione S-Transferase Mu with type 1 diabetes and its regulation with antioxidants by Sadi, Gokhan, Kartal, Deniz Irtem, Guray, Tulin

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Gene expressions of Mn-SOD and GPx-1 in streptozotocin-induced diabetes: effect of antioxidants by Sadi, Gökhan, Güray, Tülin

“…Increased oxidative stress and impaired antioxidant defense mechanisms are believed to be the important factors contributing to the pathogenesis and…”
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Changes in expression profiles of antioxidant enzymes in diabetic rat kidneys by Sadi, Gökhan, Eryilmaz, Nihan, Tütüncüoğlu, Egemen, Cingir, Şahika, Güray, Tülin

“…Background In diabetes mellitus, increased formation of reactive oxygen species due to high level of glucose in both blood plasma and tissues creates oxidative…”
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Cellular uptake, genotoxicity and cytotoxicity of cobalt ferrite magnetic nanoparticles in human breast cells by A k, Elif, Akp nar, Yeliz, Güray, N. Tülin, can, Mesude, Demircigil, Gonca Çakmak, Volkan, Mürvet

“…Magnetic nanoparticles (MNPs) have been increasingly used for many years as MRI agents and for gene delivery and hyperthermia therapy, although there have been…”
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Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in HT-29 human colon cancer cells by Altay, Ahmet, İrtem, Kartal, Sadi, Gökhan, Güray, Tülin, Yaprak, Ahmet

“…Phase I-II detoxification and antioxidant enzymes are responsible for the detoxification and elimination of activated carcinogens, acting as important…”
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Effect of vitamin C and lipoic acid on streptozotocin-induced diabetes gene expression: mRNA and protein expressions of Cu-Zn SOD and catalase by Sadi, Gökhan, Yılmaz, Ökkes, Güray, Tülin

“…The involvement of oxidative stress in the pathogenesis of diabetes mellitus has been confirmed by numerous studies. In this study, the expression of two…”
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Sheep Tissue Acetyl Coenzyme A-Dependent Arylamine N-Acetyltransferases by Guray, Tulin, Guvenc, Tugba

“…Acetyl coenzyme A-dependent arylamine N-acetyltransferases (NATs), EC 2.3.1.5. were measured in sheep tissues ( N = 14) using p-aminobenzoic acid (PABA) as a…”
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Determination of Airborne Lead Contamination in Cichorium intybus L. in an Urban Environment by YAKUPOĞLU, Dilmaç, GÜRAY, Tülin, SARICA, Deniz YURTSEVER, KAYA, Zeki

“…The major source of environmental lead (Pb) is the combustion of leaded gasoline. After emission as exhaust, lead in the air falls to earth and contaminates…”
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Purification of NADH-cytochrome b5 reductase from sheep lung and its electrophoretic, spectral and some other properties by Guray, T, Arinç, E

“…1. NADH-cytochrome b5 reductase was purified from sheep lung microsomes in the presence of non-ionic and ionic detergents, Emulgen 913 and cholate,…”
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