Search Results - "Guranda, D. T."

Chiral high-performance liquid chromatography analysis of α-amino acid mixtures using a novel SH reagent— N- R-mandelyl- l-cysteine and traditional enantiomeric thiols for precolumn derivatization by Chernobrovkin, M.G., Shapovalova, E.N., Guranda, D.T., Kudryavtsev, P.A., Švedas, V.K., Shpigun, O.A.

“…Several chiral thiols, i.e. traditionally used enantiomerically pure SH reagents and novel N- R-mandelyl- l-cysteine ( R-NMC) containing additional chiral…”
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Penicillin Acylase: A Retrospective Study of the Kinetics and Thermodynamics of Practically Significant Reactions by Panin, N. V., Guranda, D. T., Shapovalova, I. V., Švedas, V. K.

“…This review considers the contribution of works carried out at the scientific school of Ilya Vasilievich Berezin to research on the kinetics and thermodynamics…”
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Specificity of Penicillin Acylases in Deprotection of N-Benzyloxycarbonyl Derivatives of Amino Acids by Morozova, I A, Guranda, D T, Panin, N V, Švedas, V K

“…Changes in the structure of the N-acyl group in N-acylated amino acid derivatives significantly affect both the recognition and activity of penicillin acylases…”
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Aliphatic amidase from Rhodococcus rhodochrous M8 is related to the nitrilase/cyanide hydratase family by Pertsovich, S I, Guranda, D T, Podchernyaev, D A, Yanenko, A S, Svedas, V K

“…A comparative study of amino acid sequence and physicochemical properties indicates the affiliation of an amidase from Rhodococcus rhodochrous M8 (EC 3.5.1.4)…”
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pH Stability of penicillin acylase from Escherichia coli by Guranda, D T, Volovik, T S, Svedas, V K

“…The inactivation kinetics of penicillin acylase from Escherichia coli have been investigated over a wide pH range at 25 and 50 degrees C. The enzyme was very…”
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COMPARATIVE PHARMACOKINETICS AND EFFECT ON THE HEMODYNAMICS OF ORIGINAL AND GENERIC NEBIVOLOL IN HEALTHY VOLUNTEERS by Bambysheva, E. I., Isaeva, K. V., Makhinova, M. M., Guranda, D. T., Belolipetskaya, V. G.

“…Beta-blockers are an important part of modern pharmacotherapy in cardiology. The introduction of generics into clinical practice requires clear evidence of…”
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Preparation of drug polymorphs (a review) by Guranda, D. T, Gil'deeva, G. N

“…Data available in the literature concerning the screening and preparation of drug polymorphs are reviewed. The most effective methods used to obtain…”
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The role of hydrophobic interactions on alcohol binding in the active center of penicillin acylases by Chilov, G G, Guranda, D T, Svedas, V K

“…Inhibition of penicillin acylases from Escherichia coli and Alcaligenes faecalis by aliphatic and aromatic alcohols was studied. It was shown that the…”
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Penicillin Acylase-Catalyzed Effective and Stereoselective Acylation of 1-phenylethylamine in Aqueous Medium using Non-Activated Acyl Donor by Guranda, D T, Ushakov, G A, Svedas, V K

“…Until recently, the biocatalytic preparation of enantiomerically pure amines was based on stereoselective acyl transfer in an organic medium using activated…”
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A New N-Acyl Derivative of (S)-Cysteine for Quantitative Determination of Enantiomers of Amino Compounds by HPLC with a Precolumn Modification with o-Phthalaldehyde by Guranda, D. T., Shapovalova, I. V., Švedas, V. K.

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Mutation of Residue βF71 of Escherichia coli Penicillin Acylase Results in Enhanced Enantioselectivity and Improved Catalytic Properties by Shapovalova, I V, Alkema, W B L, Jamskova, O V, de Vries, E, Guranda, D T, Janssen, D B, Svedas, D B

“…Residue phenylalanine 71 of the β-chain of penicillin acylase from E. coli is involved in substrate binding and chiral discrimination of its enantiomers…”
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The influence of acetyltransferase activity phenotype on the frequency of in-stent restenosis in patient with CHD by Kuznetsova, I E, Semitko, S P, Aligishieva, Z A, Guranda, D T, Ioseliani, D G

“…Coronary artery stenting is a priority treatment of different forms of coronary heart disease. Hence, the importance of intrastent restenosis. This study…”
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Penicillin acylase-catalyzed resolution of amines in aqueous organic solvents by van Langen, L.M., Oosthoek, N.H.P., Guranda, D.T., van Rantwijk, F., Švedas, V.K., Sheldon, R.A.

“…Penicillin acylase from Alcaligenes faecalis catalyzes the enantioselective acylation of amines with phenylacetamide in a kinetically controlled reaction in…”
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Colorimetric assay of chitosan in presence of proteins and polyelectrolytes by using o-phthalaldehyde by Larionova, N.I., Zubaerova, D.K., Guranda, D.T., Pechyonkin, M.A., Balabushevich, N.G.

“…A novel approach of colorimetric quantification of chitosan based on the derivatization reaction of its primary amino groups with o-phthalaldehyde and a thiol…”
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Penicillin Acylase-Catalyzed Effective and Stereoselective Acylation of 1-phenylethylamine in Aqueous Medium using Non-Activated Acyl Donor by Guranda, D T, Ushakov, G A, Svedas, V K

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pH Stability of Penicillin Acylase from Escherichia coli by Guranda, D T, Volovik, T S, Svedas, V K

“…The inactivation kinetics of penicillin acylase from Escherichia coli have been investigated over a wide pH range at 25 and 50°C. The enzyme was very stable in…”
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Colorimetric assay of chitosan in presence of proteins and polyelectrolytes by using o-phthalaldehyde by LARIONOVA, N. I, ZUBAEROVA, D. K, GURANDA, D. T, PECHYONKIN, M. A, BALABUSHEVICH, N. G

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Mutation of Residue βF71 of Escherichia coli Penicillin Acylase Results in Enhanced Enantioselectivity and Improved Catalytic Properties by Shapovalova, I V, Alkema, W BL, Jamskova, O V, De Vries, E, Guranda, D T, Janssen, D B, Švedas, V K

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A new N-acyl derivative of (S)-cysteine for quantitative determination of enantiomers of amino compounds by HPLC method with a precolumn modification with o-phthalaldehyde by Guranda, D T, Shapovalova, I V, Shviadas, V K

“…N-Phenylacetyl-(R)-phenylglycyl-(S)-cysteine (NPPC) was used for the determination of enantiomers of primary amines by rpHPLC with a precolumn modification…”
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Cloning of penicillin acylase from Escherichia coli: Catalytic properties of recombinant enzymes by Yasnaya, A. S., Yamskova, O. V., Guranda, D. T., Shcherbakova, T. A., Tishkov, V. I., Švedas, V. K.

“…The gene of penicillin acylase (PA) from Escherichia coli has been cloned from a PA producer strain that is an analogue of strain ATCC 11105. Optimization of…”
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