Search Results - "Gupta, U.D."

Protective efficacy of Mycobacterium indicus pranii against tuberculosis and underlying local lung immune responses in guinea pig model by Gupta, Ankan, Ahmad, F.J, Ahmad, Faiz, Gupta, U.D, Natarajan, M, Katoch, V.M, Bhaskar, Sangeeta

“…Highlights ► MIP provides long-term protection as compared to BCG against tuberculosis. ► Improved granulomatous immune response in MIP-group during chronic…”
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Expression profiling of hsp70 gene during different seasons in goats (Capra hircus) under sub-tropical humid climatic conditions by Nagayach, Richi, Gupta, U.D., Prakash, Alka

“…•Quantification of hsp70 in two Indian goat breeds.•Induced expression of hsp70 in different climatic conditions.•Different tissues have variable sensibilities…”
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Gelatin nanocarriers as potential vectors for effective management of tuberculosis by Saraogi, Gaurav Kant, Gupta, Puspa, Gupta, U.D., Jain, N.K., Agrawal, G.P.

“…The aim of the research work was to develop and characterize rifampicin (RIF) loaded gelatin nanoparticulate delivery system for the effective management of…”
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Coat characteristics of goats in relation to heat tolerance in the hot tropics by Acharya, R.M, Gupta, U.D, Sehgal, J.P, Singh, M

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Molecular mimicry between Mycobacterium leprae proteins (50S ribosomal protein L2 and Lysyl-tRNA synthetase) and myelin basic protein: a possible mechanism of nerve damage in leprosy by Singh, Itu, Yadav, Asha Ram, Mohanty, Keshar Kunja, Katoch, Kiran, Sharma, Prashant, Mishra, Bishal, Bisht, Deepa, Gupta, U.D., Sengupta, Utpal

“…Autoantibodies against various components of host are known to occur in leprosy. Nerve damage is the primary cause of disability associated with leprosy. The…”
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Animal models of tuberculosis for vaccine development by Gupta, U D, Katoch, V M

“…Animal models for testing different vaccine candidates have been developed since a long time for studying tuberculosis. Mice, guinea pigs and rabbits are…”
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Animal models of tuberculosis by Gupta, U.D., Katoch, V.M.

“…It was Robert Koch who recognized the spectrum of pathology of tuberculosis (TB) in different animal species. The examination of clinical specimens from…”
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Molecular mimicry between HSP 65 of Mycobacterium leprae and cytokeratin 10 of the host keratin; Role in pathogenesis of leprosy by Singh, Itu, Yadav, Asha Ram, Mohanty, Keshar Kunja, Katoch, Kiran, Bisht, Deepa, Sharma, Prashant, Sharma, Bhawna, Gupta, U.D., Sengupta, Utpal

“…► Level of anti-keratin autoantibodies in leprosy patients are significantly higher in leprosy patients compared to healthy controls. ► Autoantibodies against…”
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Expression profile of CXCL12 chemokine during M. tuberculosis infection with different therapeutic interventions in guinea pig by Rawat, Krishan Dutta, Chahar, Mamta, Srivastava, Nalini, Gupta, U.D., Natrajan, M., Katoch, V.M., Katoch, Kiran, Chauhan, D.S.

“…•Immunoprophylaxis+chemotherapy (RvChMw) group reduced CFU as compare to other study groups entire study period.•MIP alone and Mw in with combination with…”
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Efficacy of moxifloxacin & econazole against multidrug resistant (MDR) Mycobacterium tuberculosis in murine model by Gupta, U D, Vemuri, N, Gupta, P, Kumar, V, Tanushree, P, Khuller, G K

“…Studies have shown the bactericidal potential of econazole and clotrimazole against Mycobacterium tuberculosis under in vitro and ex vivo conditions along with…”
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Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin by Lavania, Mallika, Hena, Abu, Reja, Hasanoor, Nigam, Astha, Biswas, Nibir Kumar, Singh, Itu, Turankar, Ravindra P, Gupta, Ud, Kumar, Senthil, Rewaria, Latika, Patra, Pradip K R, Sengupta, Utpal, Bhattacharya, Basudeb

“…Rifampicin is the major drug in the treatment of leprosy. The rifampicin resistance of Mycobacterium leprae results from a mutation in the rpoB gene, encoding…”
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Mycobacterium indicus pranii as stand-alone or adjunct immunotherapeutic in treatment of experimental animal tuberculosis by Faujdar, Jaya, Gupta, Pushpa, Natrajan, Mohan, Das, Ram, Chauhan, D S, Katoch, V M, Gupta, U D

“…Mycobacterium w (M.w) is a saprophytic cultivable mycobacterium and shares several antigens with M. tuberculosis. It has shown good immunomodulation in leprosy…”
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Importance of the α10 Helix for DevR Activation: A Road Map for Screening Inhibitors Against DevR-mediated Dormancy of Mycobacterium tuberculosis by Vashist, A, Prithvi Raj, D, Gupta, U.D, Bhat, R, Tyagi, J.S

“…Abstract Objective/Background Bacterial persistence is the hallmark of tuberculosis (TB) and poses the biggest threat to the success of any antitubercular drug…”
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Expression of CXCL10 (IP-10) and CXCL11 (I-TAC) chemokines during Mycobacterium tuberculosis infection and immunoprophylaxis with Mycobacterium indicus pranii (Mw) in guinea pig by Rawat, Krishna Dutta, Chahar, Mamta, Reddy, P.V.J., Gupta, Pushpa, Shrivastava, Nalini, Gupta, U.D., Natrajan, M., Katoch, V.M., Katoch, Kiran, Chauhan, D.S.

“…► Mw induces differential expression of CXCL10 and CXCL11 in TB infections. ► Chemokines are expressed in MTB infection with/without therapeutic interventions…”
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Murine model of TB meningitis by Gupta, U.D, Abbas, A, Kashyap, R.P, Gupta, P

“…Abstract Background Central nervous system (CNS) infections caused by Mycobacterium tuberculosis (MTB) are the most severe forms of extrapulmonary TB (EPTB)…”
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Comparative Evaluation of Löwenstein-Jensen Proportion Method, BacT/ALERT 3D System, and Enzymatic Pyrazinamidase Assay for Pyrazinamide Susceptibility Testing of Mycobacterium tuberculosis by Singh, Pushpendra, Wesley, Clement, Jadaun, G.P.S, Malonia, Sunil Kumar, Das, R, Upadhyay, P, Faujdar, J, Sharma, P, Gupta, P, Mishra, Abhay Kumar, Singh, Kalpana, Chauhan, D.S, Sharma, V.D, Gupta, U.D, Venkatesan, K, Katoch, V.M

“…Pyrazinamide (PZA) is an important first-line antituberculosis drug because of its sterilizing activity against semidormant tubercle bacilli. In spite of its…”
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Comparative growth pattern of multi drug resistance versus susceptible isolates of Mycobacterium tuberculosis in mice lungs by Dave, Sakshi, Faujdar, Jaya, Kumar, Praveen, Gupta, P, Das, Ram, Parasher, Deepti, Chauhan, D S, Natrajan, M, Gupta, U D, Katoch, V M

“…Rise in prevalence of multi-drug resistance (MDR) in tubercle bacilli is a serious cause of concern. As mutations with two house keeping genes rpoB and katG…”
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Highlights of the results from the GRAPES-3 experiment by Balakrishnan, Hari Haran, Ahmad, S., Chakraborty, M., Dugad, S. R., Goswami, Umananda Dev, Gupta, S. K., Hayashi, Y., Jagadeesan, P., Jain, A., Jain, P., Kawakami, S., Kojima, H., Mahapatra, S., Mohanty, P. K., Moharana, R., Muraki, Yasushi, Nayak, P. K., Nonaka, T., Oshima, A., Pattanaik, Diptiranjan, Pant, B. P., Rameez, Mohamed, Ramesh, K., Reddy, L. V., Shibata, S., Varsi, Fahim, Zuberi, M.

“…The GRAPES-3 experiment is a unique, extensive air shower experiment consisting of 400 scintillator detectors spread over 25000 m ^2 2 and a 560 m ^2 2 muon…”
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