Search Results - "Gupta, Sunetra"

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    Global burden of sickle cell anaemia in children under five, 2010-2050: modelling based on demographics, excess mortality, and interventions by Piel, Frédéric B, Hay, Simon I, Gupta, Sunetra, Weatherall, David J, Williams, Thomas N

    Published in PLoS medicine (01-07-2013)
    “…The global burden of sickle cell anaemia (SCA) is set to rise as a consequence of improved survival in high-prevalence low- and middle-income countries and…”
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    Modelling the transmission dynamics of H9N2 avian influenza viruses in a live bird market by Pinotti, Francesco, Kohnle, Lisa, Lourenço, José, Gupta, Sunetra, Hoque, Md. Ahasanul, Mahmud, Rashed, Biswas, Paritosh, Pfeiffer, Dirk, Fournié, Guillaume

    Published in Nature communications (01-05-2024)
    “…H9N2 avian influenza viruses (AIVs) are a major concern for the poultry sector and human health in countries where this subtype is endemic. By fitting a model…”
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    The roles of competition and mutation in shaping antigenic and genetic diversity in influenza by Zinder, Daniel, Bedford, Trevor, Gupta, Sunetra, Pascual, Mercedes

    Published in PLoS pathogens (01-01-2013)
    “…Influenza A (H3N2) offers a well-studied, yet not fully understood, disease in terms of the interactions between pathogen population dynamics, epidemiology and…”
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    Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000 by Piel, Frédéric B, Dr, Tatem, Andrew J, PhD, Huang, Zhuojie, PhD, Gupta, Sunetra, Prof, Williams, Thomas N, Prof, Weatherall, David J, Prof

    Published in The Lancet global health (01-02-2014)
    “…Summary Background Changes in the geographical distribution of genetic disorders are often thought to happen slowly, especially when compared with infectious…”
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    Shifting patterns of dengue three years after Zika virus emergence in Brazil by Pinotti, Francesco, Giovanetti, Marta, de Lima, Maricelia Maia, de Cerqueira, Erenilde Marques, Alcantara, Luiz C. J., Gupta, Sunetra, Recker, Mario, Lourenço, José

    Published in Nature communications (20-01-2024)
    “…In 2015, the Zika virus (ZIKV) emerged in Brazil, leading to widespread outbreaks in Latin America. Following this, many countries in these regions reported a…”
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    EPINEST, an agent-based model to simulate epidemic dynamics in large-scale poultry production and distribution networks by Pinotti, Francesco, Lourenço, José, Gupta, Sunetra, Das Gupta, Suman, Henning, Joerg, Blake, Damer, Tomley, Fiona, Barnett, Tony, Pfeiffer, Dirk, Hoque, Md Ahasanul, Fournié, Guillaume

    Published in PLoS computational biology (01-02-2024)
    “…The rapid intensification of poultry production raises important concerns about the associated risks of zoonotic infections. Here, we introduce EPINEST…”
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    Immunological serotype interactions and their effect on the epidemiological pattern of dengue by Recker, Mario, Blyuss, Konstantin B., Simmons, Cameron P., Hien, Tran Tinh, Wills, Bridget, Farrar, Jeremy, Gupta, Sunetra

    “…Long-term epidemiological data reveal multi-annual fluctuations in the incidence of dengue fever and dengue haemorrhagic fever, as well as complex cyclical…”
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    Quantifying the contribution of Plasmodium falciparum malaria to febrile illness amongst African children by Dalrymple, Ursula, Cameron, Ewan, Bhatt, Samir, Weiss, Daniel J, Gupta, Sunetra, Gething, Peter W

    Published in eLife (16-10-2017)
    “…Suspected malaria cases in Africa increasingly receive a rapid diagnostic test (RDT) before antimalarials are prescribed. While this ensures efficient use of…”
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    Potential impact of individual exposure histories to endemic human coronaviruses on age-dependent severity of COVID-19 by Pinotti, Francesco, Wikramaratna, Paul S, Obolski, Uri, Paton, Robert S, Damineli, Daniel S C, Alcantara, Luiz C J, Giovanetti, Marta, Gupta, Sunetra, Lourenço, José

    Published in BMC medicine (12-01-2021)
    “…Cross-reactivity to SARS-CoV-2 from exposure to endemic human coronaviruses (eHCoV) is gaining increasing attention as a possible driver of both protection…”
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    Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae by Watkins, Eleanor R, Penman, Bridget S, Lourenço, José, Buckee, Caroline O, Maiden, Martin C J, Gupta, Sunetra

    Published in PLoS pathogens (01-07-2015)
    “…The bacterial pathogen, Streptococcus pneumoniae (the pneumococcus), is a leading cause of life-threatening illness and death worldwide. Available conjugate…”
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    Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern by Recker, Mario, Buckee, Caroline O, Serazin, Andrew, Kyes, Sue, Pinches, Robert, Christodoulou, Zóe, Springer, Amy L, Gupta, Sunetra, Newbold, Chris I

    Published in PLoS pathogens (01-03-2011)
    “…Many pathogenic bacteria, fungi, and protozoa achieve chronic infection through an immune evasion strategy known as antigenic variation. In the human malaria…”
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    Larger mammalian body size leads to lower retroviral activity by Katzourakis, Aris, Magiorkinis, Gkikas, Lim, Aaron G, Gupta, Sunetra, Belshaw, Robert, Gifford, Robert

    Published in PLoS pathogens (01-07-2014)
    “…Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The…”
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    Pathogen selection drives nonoverlapping associations between HLA loci by Penman, Bridget S., Ashby, Ben, Buckee, Caroline O., Gupta, Sunetra

    “…Pathogen-mediated selection is commonly invoked as an explanation for the exceptional polymorphism of the HLA gene cluster, but its role in generating and…”
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    Real-time seroprevalence and exposure levels of emerging pathogens in infection-naive host populations by Pinotti, Francesco, Obolski, Uri, Wikramaratna, Paul, Giovanetti, Marta, Paton, Robert, Klenerman, Paul, Thompson, Craig, Gupta, Sunetra, Lourenço, José

    Published in Scientific reports (12-03-2021)
    “…For endemic pathogens, seroprevalence mimics overall exposure and is minimally influenced by the time that recent infections take to seroconvert. Simulating…”
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