Search Results - "Gupta, Sudhir"
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Role of dendritic cells in innate and adaptive immune response in human aging
Published in Experimental gerontology (01-06-2014)“…Aging is associated with a progressive decline in T cell function, chronic inflammation, hyperimmunoglobulinemia, autoimmunity, poor response to vaccines, and…”
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Selective IgM Deficiency-An Underestimated Primary Immunodeficiency
Published in Frontiers in immunology (05-09-2017)“…Although selective IgM deficiency (SIGMD) was described almost five decades ago, it was largely ignored as a primary immunodeficiency. SIGMD is defined as…”
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Update on Infections in Primary Antibody Deficiencies
Published in Frontiers in immunology (11-02-2021)“…Bacterial respiratory tract infections are the hallmark of primary antibody deficiencies (PADs). Because they are also among the most common infections in…”
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Impact of aging on dendritic cell functions in humans
Published in Ageing research reviews (01-07-2011)“…Abstract Aging is a paradox of reduced immunity and chronic inflammation. Dendritic cells are central orchestrators of the immune response with a key role in…”
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Role of Dendritic Cells in Inflammation and Loss of Tolerance in the Elderly
Published in Frontiers in immunology (26-07-2017)“…Dendritic cells (DCs) play an important role in advancing age-associated progressive decline in adaptive immune responses, loss of tolerance, and development…”
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Dendritic cells in inborn errors of immunity
Published in Frontiers in immunology (23-01-2023)“…Dendritic cells (DCs) are crucial cells for initiating and maintaining immune response. They play critical role in homeostasis, inflammation, and autoimmunity…”
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TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors
Published in Journal of clinical immunology (2011)“…Recently, it has been reported that using multiple signals, murine and human B cells secrete several cytokines with pro-inflammatory and immunoregulatory…”
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Editorial: Advances in Primary Immunodeficiencies in India
Published in Frontiers in immunology (24-06-2021)Get full text
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Impaired Functions of Peripheral Blood Monocyte Subpopulations in Aged Humans
Published in Journal of clinical immunology (01-11-2010)“…Aging is associated with increased susceptibility to microbial infections, and monocytes play an important role in microbial defense. In this study, we have…”
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Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction
Published in Journal of the American College of Cardiology (24-12-2019)“…Macrophages and fibroblasts are 2 major cell types involved in healing after myocardial infarction (MI), contributing to myocardial remodeling and fibrosis…”
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Constraining the flavor changing Higgs couplings to the top-quark at the LHC
Published in The journal of high energy physics (01-10-2014)“…A bstract We study the flavor-changing couplings of the Higgs-boson with the top-quark using the processes: (a) pp → tt , (b) pp → t ¯ j , and, (c) pp → t ¯ j…”
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Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)
Published in International journal of oncology (01-01-2003)“…In recent years major progress has been made in understanding the molecular steps of death receptor and mitochondrial pathway of apoptosis. Mechanisms of…”
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Editorial: Immunology of Aging
Published in Frontiers in immunology (10-07-2019)Get full text
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14
Members of the Regulatory Lymphocyte Club in Common Variable Immunodeficiency
Published in Frontiers in immunology (20-05-2022)“…The role of CD4 T regulatory cells is well established in peripheral tolerance and the pathogenesis of the murine model and human autoimmune diseases. CD4 T…”
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Molecular steps of death receptor and mitochondrial pathways of apoptosis
Published in Life Sciences (09-11-2001)“…In almost all multicellular organisms, cell suicide or apoptosis appears to play an important role in the maintenance of cellular homeostasis. Apoptosis is…”
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The anomalous Wtb vertex and top-pair production at the LHC
Published in Nuclear physics. B (01-09-2022)“…We perform an exclusive study of the anomalous Wtb interaction in the context of LHC. The limits on Wtb anomalous couplings have been estimated via the…”
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Investigating non-minimal flavour-violating CMSSM in the light of Higgs-Boson mass using information theory
Published in Nuclear physics. B (01-11-2022)“…Flavour-violating interactions of the stop-quarks are expected to provide an additional few GeV contributions to the Higgs-Boson mass, particularly when mix…”
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Phenotypically defined subpopulations of circulating follicular helper T cells in common variable immunodeficiency
Published in Immunity, Inflammation and Disease (01-09-2020)“…Background Common variable immunodeficiency (CVID) is characterized by low immunoglobulin G and IgA/IgM, decreased switched memory B cells, impaired response…”
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Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses
Published in PloS one (18-10-2010)“…Dendritic cells capture antigens through PRRs and modulate adaptive immune responses. The type of adaptive immune T cell response generated is dependent upon…”
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Higgs information in Split-SUSY at the LHC
Published in Nuclear physics. B (01-01-2023)“…Information theory turns out to be an interesting tool for studying the consequences of Higgs observations to various new physics candidate theories by means…”
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