Search Results - "Gupta, Rishikesh Kumar"

Biological and Medical Importance of Cellular Heterogeneity Deciphered by Single-Cell RNA Sequencing by Gupta, Rishikesh Kumar, Kuznicki, Jacek

“…The present review discusses recent progress in single-cell RNA sequencing (scRNA-seq), which can describe cellular heterogeneity in various organs, bodily…”
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Knockout of stim2a Increases Calcium Oscillations in Neurons and Induces Hyperactive-Like Phenotype in Zebrafish Larvae by Gupta, Rishikesh Kumar, Wasilewska, Iga, Palchevska, Oksana, Kuźnicki, Jacek

“…Stromal interaction molecule (STIM) proteins play a crucial role in store-operated calcium entry (SOCE) as endoplasmic reticulum Ca sensors. In neurons, STIM2…”
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Loss of Stim2 in zebrafish induces glaucoma-like phenotype by Baranykova, Sofiia, Gupta, Rishikesh Kumar, Kajdasz, Arkadiusz, Wasilewska, Iga, Macias, Matylda, Szybinska, Aleksandra, Węgierski, Tomasz, Nahia, Karim Abu, Mondal, Shamba S., Winata, Cecilia L., Kuźnicki, Jacek, Majewski, Lukasz

“…Calcium is involved in vision processes in the retina and implicated in various pathologies, including glaucoma. Rod cells rely on store-operated calcium entry…”
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Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons by Maciąg, Filip, Majewski, Łukasz, Boguszewski, Paweł M., Gupta, Rishikesh Kumar, Wasilewska, Iga, Wojtaś, Bartosz, Kuznicki, Jacek

“…Orai proteins form highly selective Ca2+ release-activated channels (CRACs). They play a critical role in store-operated Ca2+ entry (SOCE; i.e., the influx of…”
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stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae by Wasilewska, Iga, Gupta, Rishikesh Kumar, Wojtaś, Bartosz, Palchevska, Oksana, Kuźnicki, Jacek

“…In neurons, stromal interaction molecule (STIM) proteins regulate store-operated Ca entry (SOCE) and are involved in calcium signaling pathways. However, STIM…”
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Molecular Assessment of Epiretinal Membrane: Activated Microglia, Oxidative Stress and Inflammation by Vishwakarma, Sushma, Gupta, Rishikesh Kumar, Jakati, Saumya, Tyagi, Mudit, Pappuru, Rajeev Reddy, Reddig, Keith, Hendricks, Gregory, Volkert, Michael R, Khanna, Hemant, Chhablani, Jay, Kaur, Inderjeet

“…Fibrocellular membrane or epiretinal membrane (ERM) forms on the surface of the inner limiting membrane (ILM) in the inner retina and alters the structure and…”
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Scale-Up of an Alkaline Protease from Bacillus pumilus MTCC 7514 Utilizing Fish Meal as a Sole Source of Nutrients by Gupta, Rishikesh Kumar, Prasad, Dinesh, Sathesh, Jaykumar, Naidu, Ramachandra Boopathy, Kamini, Numbi Ramudu, Palanivel, Saravanan, Gowthaman, Marichetti Kuppuswami

“…Fish meal grades SL1 and SL2 from Sardine (Sardinella longiceps) and NJ from Pink Perch (Nemipterus japonicas) were evaluated as a sole source of carbon and…”
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Scale-Up of an Alkaline Protease from Bacillus pumilus MTCC 7514 Utilizing Fish Meal as a Sole Source of Nutrients by GUPTA RISHIKESH KUMAR, PRASAD, Dinesh, SATHESH, Jaykumar, RAMACHANDRA BOOPATHY NAIDU, NUMBI RAMUDU KAMINI, PALANIVEL, Saravanan, MARICHETTI KUPPUSWAMI GOWTHAMAN

“…Fish meal grades SL1 and SL2 from Sardine (Sardinella longiceps) and NJ from Pink Perch (Nemipterus japonicas) were evaluated as a sole source of carbon and…”
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GPCR mediated control of calcium dynamics: A systems perspective by Dhyani, Vaibhav, Gare, Suman, Gupta, Rishikesh Kumar, Swain, Sarpras, Venkatesh, K.V., Giri, Lopamudra

“…G-protein coupled receptor (GPCR) mediated calcium (Ca2+)-signaling transduction remains crucial in designing drugs for various complex diseases including…”
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FDA approved L-type channel blocker Nifedipine reduces cell death in hypoxic A549 cells through modulation of mitochondrial calcium and superoxide generation by Manohar, Kuruba, Gupta, Rishikesh Kumar, Gupta, Parth, Saha, Debasmita, Gare, Suman, Sarkar, Rahuldeb, Misra, Ashish, Giri, Lopamudra

“…As hypoxia is a major driver for the pathophysiology of COVID-19, it is crucial to characterize the hypoxic response at the cellular and molecular levels. In…”
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Non-prophylactic resveratrol-mediated protection of neurite integrity under chronic hypoxia is associated with reduction of Cav1.2 channel expression and calcium overloading by Saha, Debasmita, Vishwakarma, Sushma, Gupta, Rishikesh Kumar, Pant, Avnika, Dhyani, Vaibhav, Sharma, Sarmeela, Majumdar, Saptarshi, Kaur, Inderjeet, Giri, Lopamudra

“…Cellular hypoxia is a major cause of oxidative stress, culminating in neuronal damage in neurodegenerative diseases. Numerous ex vivo studies have implicated…”
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Identification of Zebrafish Calcium Toolkit Genes and their Expression in the Brain by Wasilewska, Iga, Gupta, Rishikesh Kumar, Palchevska, Oksana, Kuźnicki, Jacek

“…Zebrafish are well-suited for in vivo calcium imaging because of the transparency of their larvae and the ability to express calcium probes in various cell…”
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Production of α-galactosidase from Aspergillus foetidus MTCC 6322 by solid state fermentation and its application in soymilk hydrolysis by Boopathy, Naidu Ramachandra, Gupta, Rishikesh Kumar, Ramudu, Kamini Numbi

“…The production of α-galactosidase from the wild fungal strain Aspergillus foetidus MTCC 6322 using solid state fermentation (SSF), its characterization, and…”
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Diagnostic Electron Microscopy of Retina by Gupta, Rishikesh Kumar, Kaur, Inderjeet, Nag, Tapas C., Chhablani, Jay

“…The electron microscopy techniques were used in various fields as an analytical technique under in vitro conditions, which provides the sufficient resolution…”
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Confocal Imaging and k‑Means Clustering of GABAB and mGluR Mediated Modulation of Ca2+ Spiking in Hippocampal Neurons by Swain, Sarpras, Gupta, Rishikesh Kumar, Ratnayake, Kasun, Priyanka, Pantula Devi, Singh, Ranjana, Jana, Soumya, Mitra, Kishalay, Karunarathne, Ajith, Giri, Lopamudra

“…Imaging cytosolic calcium in neurons is emerging as a new tool in neurological disease diagnosis, drug screening, and toxicity testing. Ca2+ oscillation…”
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Confocal Imaging and k-Means Clustering of GABA B and mGluR Mediated Modulation of Ca 2+ Spiking in Hippocampal Neurons by Swain, Sarpras, Gupta, Rishikesh Kumar, Ratnayake, Kasun, Priyanka, Pantula Devi, Singh, Ranjana, Jana, Soumya, Mitra, Kishalay, Karunarathne, Ajith, Giri, Lopamudra

“…Imaging cytosolic calcium in neurons is emerging as a new tool in neurological disease diagnosis, drug screening, and toxicity testing. Ca oscillation…”
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Comparison of Calcium Dynamics and Specific Features for G Protein-Coupled Receptor-Targeting Drugs Using Live Cell Imaging and Automated Analysis by Gupta, Rishikesh Kumar, Swain, Sarpras, Kankanamge, Dinesh, Priyanka, Pantula Devi, Singh, Ranjana, Mitra, Kishalay, Karunarathne, Ajith, Giri, Lopamudra

“…G protein-coupled receptors (GPCRs) are targets for designing a large fraction of the drugs in the pharmaceutical industry. For GPCR-targeting drug screening…”
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Formulation and evaluation of novel stomach specific floating microspheres bearing famotidine for treatment of gastric ulcer and their radiographic study by Gupta, Rishikesh, Prajapati, Sunil Kumar, Pattnaik, Snigdha, Bhardwaj, Peeyush

“…Objective:To develop and characterize multiple-unit-type oral floating microsphere of famotidine to prolong gastric residence time and to target stomach…”
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