Search Results - "Gupta, Rinkoo D"
-
1
Chitinases from Bacteria to Human: Properties, Applications, and Future Perspectives
Published in Enzyme Research (2015)“…Chitin is the second most plenteous polysaccharide in nature after cellulose, present in cell walls of several fungi, exoskeletons of insects, and crustacean…”
Get full text
Journal Article -
2
Directed evolution of hydrolases for prevention of G-type nerve agent intoxication
Published in Nature chemical biology (01-02-2011)“…Random and targeted mutagenesis of serum paraoxonase, coupled with the development of a screen that allows detection of enzymatic activity against the toxic…”
Get full text
Journal Article -
3
An Electroactive Metallo–Polypyrene Film As A Molecular Scaffold For Multi-State Volatile Memory Devices
Published in Journal of physical chemistry. C (04-02-2016)“…In this report, an anodically electropolymerized smart film is utilized for memory storage up to quaternary states via adjustable electrical commands. The…”
Get full text
Journal Article -
4
Recent Developments Toward Antibody Engineering and Affinity Maturation
Published in Protein and peptide letters (01-01-2018)“…Monoclonal antibodies have been proven to deliver significant contribution in health industry for the development of both therapeutics and diagnostics. Efforts…”
Get more information
Journal Article -
5
Are Antimalarial Hybrid Molecules a Close Reality or a Distant Dream?
Published in Antimicrobial agents and chemotherapy (01-05-2017)“…Emergence of drug-resistant strains has led to a situation of haste in the scientific and pharmaceutical communities. Hence, all their efforts are redirected…”
Get full text
Journal Article -
6
In vitro antiplasmodial efficacy of synthetic coumarin-triazole analogs
Published in European journal of medicinal chemistry (10-02-2018)“…Twenty two diverse coumarin-triazole derivatives were synthesized by alkylation of 7-hydroxy-4-methyl-coumarin followed by click chemistry at 7-position. These…”
Get full text
Journal Article -
7
Synthesis and antimalarial activity of 7-chloroquinoline-tethered sulfonamides and their [1,2,3]-triazole hybrids
Published in Future medicinal chemistry (01-12-2022)“…Drugs with multiple bioactive moieties have the advantages of multiple modes of action and fewer chances of drug resistance. In continuation of our previous…”
Get full text
Journal Article -
8
Directed enzyme evolution via small and effective neutral drift libraries
Published in Nature methods (01-11-2008)“…Small libraries for directed evolution can be obtained by neutral drifts that maintain the protein's original function, yielding highly polymorphic, stable and…”
Get full text
Journal Article -
9
In vitro synergistic interaction of potent 4-aminoquinolines in combination with dihydroartemisinin against chloroquine-resistant Plasmodium falciparum
Published in Acta tropica (01-11-2019)“…[Display omitted] •4-Aminoquinolines were evaluated against CQ-resistant P. falciparum in combination with DHA.•Synergistic interactions were evidenced between…”
Get full text
Journal Article -
10
Synthesis, characterization, and antiplasmodial efficacy of sulfonamide‐appended [1,2,3]‐triazoles
Published in Journal of heterocyclic chemistry (01-04-2020)“…A series of benzenesulfonamide‐appended [1,2,3]‐triazole hybrids was synthesized by using [3 + 2] cycloaddition of primary, secondary, and tertiary sulfonamide…”
Get full text
Journal Article -
11
A ternary memory module using low-voltage control over optical properties of metal-polypyridyl monolayers
Published in Chemical communications (Cambridge, England) (14-04-2014)“…A ternary memory module has been designed as a function of precise voltage command. The monolayer based module displays perpetual stability and non-hysteretic…”
Get more information
Journal Article -
12
4-Aminoquinoline derivatives: Synthesis, in vitro and in vivo antiplasmodial activity against chloroquine-resistant parasites
Published in European journal of medicinal chemistry (21-10-2016)“…Synthetic quinoline derivatives continue to be considered as candidates for new drug discovery if they act against CQ-resistant strains of malaria even after…”
Get full text
Journal Article -
13
Molecular logic operations based on optical detection of sulfur mustard simulant using pyridine appended Mg–porphyrazine complex
Published in Sensors and actuators. B, Chemical (01-05-2016)“…Selective detection of sulfur mustard simulant, 2-chloroethyl ethyl sulfide (CEES) is performed using specifically designed pyridine appended Mg–porphyrazine…”
Get full text
Journal Article -
14
Chromogenic Homo-Dinuclear Ruthenium(II) Monolayer as a Tunable Molecular Memory Module for Multibit Information Storage
Published in Journal of physical chemistry. C (05-03-2015)“…A molecular-module comprising of a surface-confined optically rich and redox active homobimetallic chromophore on siloxane-based templates, has been obtained…”
Get full text
Journal Article -
15
Surface confined heteroleptic copper(II)-polypyridyl complexes for photonuclease activity
Published in Chemical communications (Cambridge, England) (09-10-2014)“…Heteroleptic copper(II)-polypyridyl complexes with extended π-conjugated, aromatic terminal units were immobilized on glass/Si substrates to intercalate DNA…”
Get more information
Journal Article -
16
In vitro synergistic effect of fluoroquinolone analogues in combination with artemisinin against Plasmodium falciparum; their antiplasmodial action in rodent malaria model
Published in Malaria journal (05-02-2015)“…Emergence of drug-resistant parasite strains has surfaced as a major obstacle in attempts to ameliorate malaria. Current treatment regimen of malaria relies on…”
Get full text
Journal Article -
17
Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase
Published in Chemistry & biology (17-12-2015)“…Mycobacterium tuberculosis (Mtb) can survive in hypoxic necrotic tissue by assimilating energy from host-derived fatty acids. While the expanded repertoire of…”
Get full text
Journal Article -
18
Stepwise substitution of oxo-centered, trinuclear chromium(III) carboxylates with Schiff base
Published in Transition metal chemistry (Weinheim) (01-05-2007)“…Oxo-centered, trinuclear, mixed-ligand complexes of chromium(III) have been synthesized by stepwise substitutions of acetate ions of [Cr^sub 3^O(OOCMe)^sub…”
Get full text
Journal Article -
19
Addressing of multiple-metal ions on a single platform
Published in Coordination chemistry reviews (15-05-2015)“…•We compile chemosensors capable of simultaneous recognition of multiple metal ions.•Two major approaches adopted by multi-signaling chemosensors have been…”
Get full text
Journal Article -
20
Synthesis and Antimalarial Evaluation of [1, 2,3]‐Triazole‐Tethered Sulfonamide‐Berberine Hybrids
Published in ChemistrySelect (Weinheim) (14-09-2018)“…Malaria still remains a global health problem despite of the availability of effective control and treatment measures. In the present study, a novel series of…”
Get full text
Journal Article