Search Results - "Gupta, Prerak"
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Biomimetic, Osteoconductive Non-mulberry Silk Fiber Reinforced Tricomposite Scaffolds for Bone Tissue Engineering
Published in ACS applied materials & interfaces (16-11-2016)“…Composite biomaterials as artificial bone graft materials are pushing the present frontiers of bioengineering. In this study, a biomimetic, osteoconductive…”
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Deterministic Single Cell Encapsulation in Asymmetric Microenvironments to Direct Cell Polarity
Published in Advanced science (01-01-2023)“…Various signals in tissue microenvironments are often unevenly distributed around cells. Cellular responses to asymmetric cell‐matrix adhesion in a 3D space…”
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Mesenchymal Stem Cell-Conditioned Media-Loaded Microparticles Enhance Acute Patency in Silk-Based Vascular Grafts
Published in Bioengineering (Basel) (21-09-2024)“…Coronary artery disease leads to over 360,000 deaths annually in the United States, and off-the-shelf bypass graft options are currently limited and/or have…”
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4
Tissue‐Engineered Vascular Grafts: Emerging Trends and Technologies
Published in Advanced functional materials (01-08-2021)“…Vascular tissue engineering has made prodigious progress in recent years by converging multidisciplinary approaches. Latest technological advancements foster…”
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Towards single cell encapsulation for precision biology and medicine
Published in Advanced drug delivery reviews (01-10-2023)“…[Display omitted] The primary impetus of therapeutic cell encapsulation in the past several decades has been to broaden the options for donor cell sources by…”
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Silk biomaterials for vascular tissue engineering applications
Published in Acta biomaterialia (15-10-2021)“…Vascular tissue engineering is a rapidly growing field of regenerative medicine, which strives to find innovative solutions for vascular reconstruction…”
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Immunomodulatory injectable silk hydrogels maintaining functional islets and promoting anti-inflammatory M2 macrophage polarization
Published in Biomaterials (01-12-2018)“…Islet transplantation is considered the most promising treatment for type 1 diabetes. However, the clinical success is limited by islet dysfunction in…”
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Silk-microfluidics for advanced biotechnological applications: A progressive review
Published in Biotechnology advances (01-09-2016)“…Silk based biomaterials have not only carved a unique niche in the domain of regenerative medicine but new avenues are also being explored for lab-on-a-chip…”
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Fabrication of Small-Diameter Tubular Grafts for Vascular Tissue Engineering Applications Using Mulberry and Non-mulberry Silk Proteins
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Silk fibroin (SF) is a natural well-known biomaterial that has widely been explored for various tissue engineering applications with great success. Herein, we…”
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10
Mimicking Form and Function of Native Small Diameter Vascular Conduits Using Mulberry and Non-mulberry Patterned Silk Films
Published in ACS applied materials & interfaces (29-06-2016)“…Autologous graft replacement as a strategy to treat diseased peripheral small diameter (≤6 mm) blood vessel is often challenged by prior vein harvesting. To…”
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11
Bioresorbable silk grafts for small diameter vascular tissue engineering applications: In vitro and in vivo functional analysis
Published in Acta biomaterialia (15-03-2020)“…The success of tissue-engineered vascular graft (TEVG) predominantly relies on the selection of a suitable biomaterial and graft design. Natural biopolymer…”
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Coordination-Driven Self-Assembly of Ionic Irregular Hexagonal Metallamacrocycles via an Organometallic Clip and Their Cytotoxicity Potency
Published in Inorganic chemistry (02-04-2018)“…Two new irregular hexagons (6 and 7) were synthesized from a pyrazine motif containing an organometallic acceptor clip [bearing platinum(II) centers] and…”
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13
Notch transcriptional target tmtc1 maintains vascular homeostasis
Published in Cellular and molecular life sciences : CMLS (27-08-2024)“…Proper lung function requires the maintenance of a tight endothelial barrier while simultaneously permitting the exchange of macromolecules and fluids to…”
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14
Extracellular Vesicles Enhance the Remodeling of Cell-Free Silk Vascular Scaffolds in Rat Aortae
Published in ACS applied materials & interfaces (17-06-2020)“…Vascular tissue engineering is aimed at developing regenerative vascular grafts to restore tissue function by bypassing or replacing defective arterial…”
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Functionalized Silk Vascular Grafts with Decellularized Human Wharton's Jelly Improves Remodeling via Immunomodulation in Rabbit Jugular Vein
Published in Advanced healthcare materials (01-10-2021)“…Cell‐free polymeric tissue‐engineered vascular grafts (TEVGs) have shown great promise towards clinical translation; however, their limited bioactivity and…”
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High performance bio-based hyperbranched polyurethane/carbon dot-silver nanocomposite: a rapid self-expandable stent
Published in Biofabrication (27-10-2016)“…Development of a bio-based smart implantable material with multifaceted attributes of high performance, potent biocompatibility and inherent antibacterial…”
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Smart self-tightening surgical suture from a tough bio-based hyperbranched polyurethane/reduced carbon dot nanocomposite
Published in Biomedical materials (Bristol) (16-04-2018)“…Design and fabrication of a smart bio-based polymeric material with potent biocompatibility and high performance still remain a challenge in the biomedical…”
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Surface Patterning and Innate Physicochemical Attributes of Silk Films Concomitantly Govern Vascular Cell Dynamics
Published in ACS biomaterials science & engineering (11-02-2019)“…Functional impairment of vascular cells is associated with cardiovascular pathologies. Recent literature clearly presents evidence relating cell…”
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In Vitro Culture of Human Corneal Endothelium on Non-Mulberry Silk Fibroin Films for Tissue Regeneration
Published in Translational vision science & technology (01-03-2020)“…The purpose of this study was to determine if non-mulberry varieties of silk are suitable for the culture of corneal endothelium (CE). Aqueous silk fibroin…”
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CCL2 loaded microparticles promote acute patency in silk-based vascular grafts implanted in rat aortae
Published in Acta biomaterialia (01-11-2021)“…Cardiovascular disease is the leading cause of death worldwide, often associated with coronary artery occlusion. A common intervention for arterial blockage…”
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