Search Results - "Gupta, Manish"
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Recent synthetic and medicinal perspectives of dihydropyrimidinones: A review
Published in European journal of medicinal chemistry (26-05-2017)“…Dihydropyrimidines are the most important heterocyclic ring systems which play an important role in the synthesis of DNA and RNA. Synthetically they were…”
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2
Outlier Detection for Temporal Data: A Survey
Published in IEEE transactions on knowledge and data engineering (01-09-2014)“…In the statistics community, outlier detection for time series data has been studied for decades. Recently, with advances in hardware and software technology,…”
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3
Transdermal drug delivery systems in diabetes management: A review
Published in Asian journal of pharmceutical sciences (01-01-2020)“…Diabetes mellitus is a chronic disease in which there is an insufficient production of insulin by the pancreas, or the insulin produced is unable to be…”
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4
Family of Constrained Codes for Archival DNA Data Storage
Published in IEEE communications letters (01-10-2018)“…DNA-based data storage systems have evolved as a solution to accommodate data explosion. In this letter, some properties of DNA codewords that are essential…”
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5
Immune Checkpoint inhibitors: An introduction to the next-generation cancer immunotherapy
Published in Journal of clinical pharmacology (01-02-2016)“…Activating the immune system to eliminate cancer cells and produce clinically relevant responses has been a long‐standing goal of cancer research. Most…”
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6
Mutation informatics: SARS-CoV-2 receptor-binding domain of the spike protein
Published in Drug discovery today (01-10-2022)“…•Mutation informatics study on RBD of SARS-CoV-2 variants.•Discussion of small molecules targeting the RBD/ACE2 interface.•Ideation to design novel inhibitors…”
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7
Natural deep eutectic solvents-based concurrent approach for qualitative and quantitative enhancement of Rosa damascena essential oil and recovery of phenolics from distilled rose petals
Published in Separation and purification technology (19-02-2025)“…[Display omitted] •Effect of NADES on essential oil (EO) yield enhancement and phenolic enrichment in distillation waste of Rosa damascena.•Non acidic hydrogen…”
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Ru(II)-Catalyzed C(sp2)–H Activation Annulation: Synthesis of Fluorescent Benzoisoquinolonyl Acetate/Peptides from N‑Arylamides and Ethyne at Room Temperature
Published in Journal of organic chemistry (15-05-2024)“…Benzoisoquinolones are aryl ring extended isoquinolinone derivatives, which are constituents of alkaloid natural products. This report describes the synthesis…”
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An efficient statistical feature selection approach for classification of gene expression data
Published in Journal of biomedical informatics (01-08-2011)“…Classification of gene expression data plays a significant role in prediction and diagnosis of diseases. Gene expression data has a special characteristic that…”
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10
Endophytic Fungi: A Source of Potential Antifungal Compounds
Published in Journal of fungi (Basel) (25-06-2018)“…The emerging and reemerging forms of fungal infections encountered in the course of allogeneic bone marrow transplantations, cancer therapy, and organ…”
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Synthesis of N -isoindolinonyl peptides via Pd-catalyzed C(sp 2 )-H olefination-activation and their conformational studies
Published in Organic & biomolecular chemistry (21-06-2023)“…Isoindolinone is a constituent of several natural products that show a wide range of bioactivity, such as anticancer, antimicrobial, antiviral and…”
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12
Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…Cancer is second leading disease after cardiovascular disease. Presently, Chemotherapy, Radiotherapy and use of chemicals are some treatments available these…”
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13
Impact of Post Hardening Mechanism on Self-Healing Assessment of AA2014 Nitinol-Based Smart Composites
Published in Metals and materials international (01-08-2021)“…Exploring the self-healing capability in a metallic system, an experimental study was carried out for AA2014 and Nitinol-based smart composites material. The…”
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14
A new amino acid, hybrid peptides and BODIPY analogs: synthesis and evaluation of 2-aminotroponyl-L-alanine (ATA) derivatives
Published in Organic & biomolecular chemistry (07-12-2022)“…Natural aromatic α-amino acid residues play critical roles in the structural and functional organization of proteins owing to π-interactions. Their aromatic…”
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UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised Hearts
Published in Circulation research (10-06-2016)“…RATIONALE:SUMOylation plays an important role in cardiac function and can be protective against cardiac stress. Recent studies show that SUMOylation is an…”
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Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies
Published in Bioorganic & medicinal chemistry letters (01-09-2017)“…[Display omitted] •Design of isatin-coumarin hybrids based on the cytotoxicity of each pharmacophore.•Synthesis of 28 novel isatin-coumarin hybrids using click…”
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Post-term Birth and Developmental Coordination Disorder: A Narrative Review of Motor Impairments in Children
Published in Curēus (Palo Alto, CA) (26-06-2024)“…A prevalent long-term medical condition in children that is rarely understood and acknowledged in educational contexts is developmental coordination disorder…”
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Agonist, antagonist and signaling modulators of ABA receptor for agronomic and post-harvest management
Published in Plant physiology and biochemistry (01-03-2020)“…Abscisic acid (ABA) is a ubiquitous phytohormone, plays important roles in several physiological processes, including stress adaptation, flowering, seed…”
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Smart Advancements for Targeting Solid Tumors via Protein and Peptide Drug Delivery (PPD)
Published in Current drug delivery (01-01-2023)“…Proteins and peptides possess considerable potential in treating solid tumors because of their unique properties. At present, there are over 100 peptide-based…”
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Circulating microRNA‐590‐5p functions as a liquid biopsy marker in non‐small cell lung cancer
Published in Cancer science (01-03-2020)“…Despite the availability of various diagnostic procedures, a tissue biopsy is still indispensable for the routine diagnosis of lung cancer. However, inaccurate…”
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