Search Results - "Gupta, Kunj Bihari"

Role of immune system in tumor progression and carcinogenesis by Upadhyay, Shishir, Sharma, Nidhi, Gupta, Kunj Bihari, Dhiman, Monisha

“…Tumor micro‐environment has potential to customize the behavior of the immune cell according to their need. In immune‐eliminating phase, immune cells eliminate…”
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A short review: Doxorubicin and its effect on cardiac proteins by Upadhyay, Shishir, Gupta, Kunj Bihari, Mantha, Anil Kumar, Dhiman, Monisha

“…Doxorubicin (DOX) is a boon for cancer‐suffering patients. However, the undesirable effect on health on vital organs, especially the heart, is a limiting…”
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New pentacyclic triterpene from Potentilla atrosanguinea Lodd. as anticancer agent for breast cancer targeting estrogen receptor-α by Kumar, Amit, Gupta, Kunj Bihari, Dhiman, Monisha, Arora, Saroj, Jaitak, Vikas

“…One new (compound 3) along with two previously known ursane type triterpenoids (compounds 1 and 2) were purified by chromatographic techniques from ethyl…”
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Gliadin induced oxidative stress and altered cellular responses in human intestinal cells: An in‐vitro study to understand the cross‐talk between the transcription factor Nrf‐2 and multifunctional APE1 enzyme by Gupta, Kunj Bihari, Dhiman, Monisha, Mantha, Anil Kumar

“…The present study examined the wheat protein gliadin‐induced oxidative and nitrosative stress and its downstream responses in human intestinal HCT‐116 and…”
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Parthenium hysterophorus mediated inflammation and hyper‐responsiveness via NF‐κB pathway in human A549 lung cancer cell line by Kaur, Mandeep, Gupta, Kunj Bihari, Thakur, Shweta, Kaur, Sukhchain, Dhiman, Monisha

“…Being one of the notorious weed P. hysterophorus has invaded almost every part India and is the lead cause of skin allergies and severe dermatitis among…”
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Mitigation of Gliadin-Induced Inflammation and Cellular Damage by Curcumin in Human Intestinal Cell Lines by Gupta, Kunj Bihari, Mantha, Anil K., Dhiman, Monisha

“…Wheat is a major diet from many years; apart from its nutritious value, the wheat protein gliadin is responsible for many inflammatory diseases like celiac…”
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Risk factors for fecal carriage of carbapenemase producing Enterobacteriaceae among intensive care unit patients from a tertiary care center in India by Mittal, Gajanand, Gaind, Rajni, Kumar, Deepak, Kaushik, Gaurav, Gupta, Kunj Bihari, Verma, P K, Deb, Monorama

“…Resistance amongst the commensal flora is a serious threat because a very highly populated ecosystem like the gut, may at a later stage, be a source of extra…”
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Cytotoxic Autophagy: A Novel Treatment Paradigm against Breast Cancer Using Oleanolic Acid and Ursolic Acid by Gupta, Kunj Bihari, Gao, Jie, Li, Xin, Thangaraju, Muthusamy, Panda, Siva S, Lokeshwar, Bal L

“…Oleanolic acid (OA) and Ursolic acid (UA) are bioactive triterpenoids. Reported activities vary with the dose used for testing their activities in vitro…”
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Identification of novel indole based heterocycles as selective estrogen receptor modulator by Singla, Ramit, Prakash, Kunal, Bihari Gupta, Kunj, Upadhyay, Shishir, Dhiman, Monisha, Jaitak, Vikas

“…[Display omitted] •Indole heterocycles were rationally designed and synthesised as SERM.•Compounds 5c and 6d reduced the mRNA and protein expression of…”
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Curcumin-Dichloroacetate Hybrid Molecule as an Antitumor Oral Drug against Multidrug-Resistant Advanced Bladder Cancers by Gupta, Kunj Bihari, Taylor, Truett L, Panda, Siva S, Thangaraju, Muthusamy, Lokeshwar, Bal L

“…Tumor cells produce excessive reactive oxygen species (ROS) but cannot detoxify ROS if they are due to an external agent. An agent that produces toxic levels…”
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Ursolic Acid Conjugates: A New Frontier in Anticancer Drug Development by Bokhtia, Riham M., Pham, Ashley M., Bihari Gupta, Kunj, Warang, Shamta S., Venugopal, Natasha, Shakuja, Rajeev, Somanath, Payaningal R., Liu, Fang, Chang Jeon, Yi, Guimaraes, Guilherme J., Bartlett, Michael G., Thangaraju, Muthusamy, Lokeshwar, Bal. L., Panda, Siva S.

“…New Ursolic Acid (UA) conjugates were synthesized using optimized synthetic protocols through the molecular hybridization approach at C‐3 and C‐28. This…”
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Yokenella regensburgei infection in India mimicking enteric fever by JAIN, Sarika, GAIND, Rajni, KUNJ BIHARI GUPTA, DAWAR, Reetika, KUMAR, Deepak, PAUL, Premila, SARDANA, Raman, DEB, Manorama

“…Yokenella regensburgei is an opportunistic human pathogen of the Enterobacteriaceae family rarely reported to cause human infections. Here, we present a case…”
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Micropropagation protocol for Salvadora oleoides by Kumar, Ravindra, Najar, Raoof Ahmad, Gupta, Kunj Bihari, Saini, Ram Gopal

“…Salvadora oleoides Decne. is a pharmaceutically important plant. Owing to poor seed formation, viability and, germination, and to anthropogenic disturbances,…”
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Design, synthesis and biological evaluation of novel indole-benzimidazole hybrids targeting estrogen receptor alpha (ER-α) by Singla, Ramit, Gupta, Kunj Bihari, Upadhyay, Shishir, Dhiman, Monisha, Jaitak, Vikas

“…In the course of efforts to develop novel selective estrogen receptor modulators (SERMs), indole-benzimidazole hybrids were designed and synthesised by fusing…”
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Methods to Detect Nitric Oxide and Reactive Nitrogen Species in Biological Sample by Kaur, Sharanjot, Gupta, Kunj Bihari, Kumar, Sandeep, Upadhyay, Shishir, Mantha, Anil Kumar, Dhiman, Monisha

“…Oxidative stress has been implicated in various human diseases, including cancer, mainly through the generation of reactive nitrogen species (RNS), such as…”
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Design, synthesis and biological evaluation of novel indole-xanthendione hybrids as selective estrogen receptor modulators by Singla, Ramit, Gupta, Kunj Bihari, Upadhyay, Shishir, Dhiman, Monisha, Jaitak, Vikas

“…[Display omitted] •Rationally design and synthesis of Indole-xanthendione hybrids as SERM is proposed.•Compounds exhibit potent antiproliferative and ER-α…”
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Characterisation and antimicrobial resistance of sepsis pathogens in neonates born in tertiary care centres in Delhi, India: a cohort study

“…Summary Background Sepsis is one of the most common causes of neonatal deaths globally. Most sepsis-related deaths occur in low-income and middle-income…”
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Methods to Assess Oxidative DNA Base Damage Repair of Apurinic/Apyrimidinic (AP) Sites Using Radioactive and Nonradioactive Oligonucleotide-Based Assays by Gupta, Kunj Bihari, Kaur, Sharanjot, Dhiman, Monisha, Mantha, Anil Kumar

“…Reactive oxygen species (ROS) overproduction results in oxidative stress leading to genomic instability via the generation of small base lesions in the genome,…”
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Inflammatory response of gliadin protein isolated from various wheat varieties on human intestinal cell line by Gupta, Kunj Bihari, Upadhyay, Shishir, Saini, Ram Gopal, Mantha, Anil K., Dhiman, Monisha

“…Wheat protein contributes a significant part in human diet, apart from its well-known nutritional values, wheat gluten/gliadin proteins are also responsible…”
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Abstract 4558: A triterpenoid derivative has strong antitumor activities in gemcitabine-resistant advanced bladder cancer models and promotes immune cell infiltration in a high grade murine syngeneic model by Seremak, Juliette Rose, Gupta, Kunj Bihari, Panda, Siva S., Lokeshwar, Bal L.

“…Abstract Bladder cancer (BC) presents a formidable challenge in treatment and patient survival, requiring particular attention to advanced stages, such as…”
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