Search Results - "Gupta, Amit Chand"
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Nanoemulsion preconcentrate of a pentacyclic triterpene for improved oral efficacy: Formulation design and in-vivo antimalarial activity
Published in Journal of drug delivery science and technology (01-06-2020)“…In order to develop new lead from plant, natural product drug discovery is one of the popular choices which deal numerous unprecedented challenges. Lupeol, a…”
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Ameliorative Effects of Dietary Ellagic Acid Against Severe Malaria Pathogenesis by Reducing Cytokine Storms and Oxidative Stress
Published in Frontiers in pharmacology (09-12-2021)“…Ellagic acid (EA), a fruit- and vegetable-derived flavonoid, has been reported for multiple pharmacological activities, which encouraged us to examine its…”
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Aromatic ginger (Kaempferia galanga L.) extracts with ameliorative and protective potential as a functional food, beyond its flavor and nutritional benefits
Published in Toxicology reports (01-01-2019)“…[Display omitted] •Aromatic ginger is rich in essential nutrients showing potential chemopreventive potential.•Dried aromatic ginger and its hydro-distillate…”
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Design, synthesis and drug resistance reversal potential of novel curcumin mimics Van D: Synergy potential of curcumin mimics
Published in Bioorganic chemistry (01-01-2021)“…Being crucial part of plant-based novel discovery of drug from natural resources, a study was done to explore the antibacterial potential of curcumin mimics in…”
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Bivalent furostene carbamates as antiproliferative and antiinflammatory agents
Published in The Journal of steroid biochemistry and molecular biology (01-11-2019)“…Carbamate derivative at C26 of furostene ring after opening spiroketal bond (F-ring) of diosgenin exhibits potent anticancer activity against breast Cancer…”
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Plumbagin, a vitamin K3 analogue ameliorate malaria pathogenesis by inhibiting oxidative stress and inflammation
Published in Inflammopharmacology (01-08-2018)“…Plumbagin, a vitamin K3 analogue is the major active constituent in several plants including root of Plumbago indica Linn . This compound has been shown to…”
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Synthesis of eugenol derivatives and its anti-inflammatory activity against skin inflammation
Published in Natural product research (17-01-2020)“…Eugenol is a phytochemical present in aromatic plants has generated considerable interest in the pharmaceutical industries mainly in cosmetics. A series of…”
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(22β,25R)-3β-Hydroxy-spirost-5-en-7-iminoxy-heptanoic acid exhibits anti-prostate cancer activity through caspase pathway
Published in Steroids (01-03-2017)“…[Display omitted] •Diverse long chain fatty acid/esters of diosgenin-7-ketoxime have been prepared.•Analogue 16, cytotoxicity IC50=12μM prostate cancer, cell…”
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Design, synthesis and drug resistance reversal potential of novel curcumin mimics Van D
Published in Bioorganic chemistry (01-01-2021)“…[Display omitted] •Highly conjugated curcumin mimics were synthesized for structural similarity.•Curcumin mimics, Van D exhibited drug resistance reversal…”
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