Search Results - "Gupta, Alejandro J"

Linking single-cell measurements of mass, growth rate, and gene expression by Kimmerling, Robert J, Prakadan, Sanjay M, Gupta, Alejandro J, Calistri, Nicholas L, Stevens, Mark M, Olcum, Selim, Cermak, Nathan, Drake, Riley S, Pelton, Kristine, De Smet, Frederik, Ligon, Keith L, Shalek, Alex K, Manalis, Scott R

“…Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform…”
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Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer by Hamza, Bashar, Ng, Sheng Rong, Prakadan, Sanjay M., Delgado, Francisco Feijó, Chin, Christopher R., King, Emily M., Yang, Lucy F., Davidson, Shawn M., DeGouveia, Kelsey L., Cermak, Nathan, Navia, Andrew W., Winter, Peter S., Drake, Riley S., Tammela, Tuomas, Li, Carman Man-Chung, Papagiannakopoulos, Thales, Gupta, Alejandro J., Bagnall, Josephine Shaw, Knudsen, Scott M., Vander Heiden, Matthew G., Wasserman, Steven C., Jacks, Tyler, Shalek, Alex K., Manalis, Scott R.

“…Circulating tumor cells (CTCs) play a fundamental role in cancer progression. However, in mice, limited blood volume and the rarity of CTCs in the bloodstream…”
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Linking Biophysical and Transcriptional Profiles of In Vivo-Treated Human Leukemias on a Single-Cell Level Uniquely Resolves Subpopulations of Response by Murakami, Mark A., Stevens, Mark M, Kimmerling, Robert J, Gupta, Alejandro J, Liu, Huiyun, Prakadan, Sanjay M., Shalek, Alex K., Manalis, Scott R., Weinstock, David M.

“…Introduction: Assays are needed to define the susceptibility of heterogeneous primary human tumor cells. We previously showed that single-cell mass…”
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