Search Results - "Guo Yuxuan"
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1
Off-target effects in CRISPR/Cas9 gene editing
Published in Frontiers in bioengineering and biotechnology (09-03-2023)“…Gene editing stands for the methods to precisely make changes to a specific nucleic acid sequence. With the recent development of the clustered regularly…”
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2
A framework for selecting and assessing soil quality indicators for sustainable soil management in waste dumps
Published in Scientific reports (11-04-2024)“…The primary objective of this study was to develop soil quality indexes (SQIs) to reveal the changes in SQ during the restoration of vegetation in the…”
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3
Lamins position the nuclear pores and centrosomes by modulating dynein
Published in Molecular biology of the cell (01-10-2015)“…Lamins, the type V nuclear intermediate filament proteins, are reported to function in both interphase and mitosis. For example, lamin deletion in various cell…”
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4
Monitoring of the central blood pressure waveform via a conformal ultrasonic device
Published in Nature biomedical engineering (01-09-2018)“…Continuous monitoring of the central blood pressure waveform from deeply embedded vessels such as the carotid artery and jugular vein has clinical value for…”
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5
Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation
Published in Circulation research (05-01-2018)“…RATIONALE:Although mitochondrial diseases often cause abnormal myocardial development, the mechanisms by which mitochondria influence heart growth and function…”
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6
Topic change point detection using a mixed Bayesian model
Published in Data mining and knowledge discovery (2022)“…Dynamic text documents, including news articles, user reviews, and blogs, are now commonly encountered in many fields. Accordingly, the topics underlying text…”
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7
Genetic Mosaics for Greater Precision in Cardiovascular Research
Published in Circulation research (22-06-2018)“…Interpretation of cardiac gain- and loss- of function experiments are prone to secondary, indirect effects that confound and obscure data interpretation. We…”
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Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo
Published in Circulation research (09-06-2017)“…RATIONALE:Loss-of-function studies in cardiac myocytes (CMs) are currently limited by the need for appropriate conditional knockout alleles. The factors that…”
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9
Active conformation of the p97-p47 unfoldase complex
Published in Nature communications (12-05-2022)“…The p97 AAA+ATPase is an essential and abundant regulator of protein homeostasis that plays a central role in unfolding ubiquitylated substrates. Here we…”
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10
Towards a Novel Generative Adversarial Network-Based Framework for Remote Sensing Image Demosaicking
Published in Remote sensing (Basel, Switzerland) (01-07-2024)“…During satellite remote sensing imaging, the use of Bayer mode sensors holds significant importance in saving airborne computing resources and reducing the…”
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11
Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction
Published in Oxidative medicine and cellular longevity (2020)“…Oxidative stress aggravates mitochondrial injuries and accelerates the proliferation of vascular smooth muscle cells (VSMCs), which are important mechanisms…”
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12
Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation
Published in Nature communications (21-07-2021)“…The forward genetic screen is a powerful, unbiased method to gain insights into biological processes, yet this approach has infrequently been used in vivo in…”
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13
CMYA5 establishes cardiac dyad architecture and positioning
Published in Nature communications (21-04-2022)“…Cardiac excitation-contraction coupling requires dyads, the nanoscopic microdomains formed adjacent to Z-lines by apposition of transverse tubules and…”
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14
Periodontal disease and myocardial infarction risk: A meta-analysis of cohort studies
Published in The American journal of emergency medicine (01-10-2021)“…The objective of this meta-analysis was to systematically assess the association between periodontal disease (PD) and myocardial infarction (MI). We searched…”
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15
Sorafenib induces cardiotoxicity through RBM20-mediated alternative splicing of sarcomeric and mitochondrial genes
Published in Pharmacological research (01-12-2023)“…Sorafenib, a multi-targeted tyrosine kinase inhibitor, is a first-line treatment for advanced solid tumors, but it induces many adverse cardiovascular events,…”
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16
Enhanced Water Resistance of TiO2–GO–SMS-Modified Soil Composite for Use as a Repair Material in Earthen Sites
Published in Materials (20-09-2024)“…Most earthen sites are located in open environments eroded by wind and rain, resulting in spalling and cracking caused by shrinkage due to constant water…”
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17
Increased Reactive Oxygen Species–Mediated Ca2+/Calmodulin-Dependent Protein Kinase II Activation Contributes to Calcium Handling Abnormalities and Impaired Contraction in Barth Syndrome
Published in Circulation (New York, N.Y.) (11-05-2021)“…BACKGROUNDMutations in tafazzin (TAZ), a gene required for biogenesis of cardiolipin, the signature phospholipid of the inner mitochondrial membrane, causes…”
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18
Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling
Published in Proceedings of the National Academy of Sciences - PNAS (12-01-2021)“…The paucity of knowledge about cardiomyocyte maturation is a major bottleneck in cardiac regenerative medicine. In development, cardiomyocyte maturation is…”
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19
Ambient and focal attention during complex problem-solving: preliminary evidence from real-world eye movement data
Published in Frontiers in psychology (15-02-2024)“…Time course analysis of eye movements during free exploration of real-world scenes often reveals an increase in fixation durations together with a decrease in…”
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Release of biogenic volatile organic compounds and physiological responses of two sub-tropical tree species to smoke derived from forest fire
Published in Ecotoxicology and environmental safety (15-04-2024)“…Forests emit a large amount of biogenic volatile organic compounds (BVOCs) in response to biotic and abiotic stress. Despite frequent occurrence of large…”
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