Search Results - "Guo Huichen"
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Heterogeneous synthesis of nitrogen-doped carbon dots prepared via anhydrous citric acid and melamine for selective and sensitive turn on-off-on detection of Hg (II), glutathione and its cellular imaging
Published in Sensors and actuators. B, Chemical (01-02-2018)“…The N-CDs could be potentially utilized as an excellent optical sensor for the quantitative analysis of Hg (II) or GSH in living cells. [Display omitted]…”
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Singlet oxygen-induced apoptosis of cancer cells using upconversion fluorescent nanoparticles as a carrier of photosensitizer
Published in Nanomedicine (01-06-2010)“…Abstract The photodynamic effect of upconversion nanoparticles loaded with a photosensitizer was studied on murine bladder cancer cells (MB49). Mesoporous…”
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Ribosomal Protein L13 Promotes IRES-Driven Translation of Foot-and-Mouth Disease Virus in a Helicase DDX3-Dependent Manner
Published in Journal of virology (06-01-2020)“…Internal ribosome entry site (IRES)-driven translation is a common strategy among positive-sense, single-stranded RNA viruses for bypassing the host cell…”
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Advances and Breakthroughs in IRES-Directed Translation and Replication of Picornaviruses
Published in mBio (25-04-2023)“…Viruses lack the properties to replicate independently due to the limited resources encoded in their genome; therefore, they hijack the host cell machinery to…”
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Use of virus-like particles and nanoparticle-based vaccines for combating picornavirus infections
Published in Veterinary research (Paris) (30-09-2024)“…Picornaviridae are non-enveloped ssRNA viruses that cause diseases such as poliomyelitis, hand-foot-and-mouth disease (HFMD), hepatitis A, encephalitis,…”
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Foot-and-mouth disease virus antigenic landscape and reduced immunogenicity elucidated in atomic detail
Published in Nature communications (10-10-2024)“…Unlike most other picornaviruses, foot-and-mouth disease (FMD) intact virions (146S) dissociate easily into small pentameric subunits (12S). This causes a…”
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Imidazole derivative-functionalized carbon dots: using as a fluorescent probe for detecting water and imaging of live cells
Published in Dalton transactions : an international journal of inorganic chemistry (28-03-2015)“…A highly sensitive carbon dot-imidazole (CD-imidazole) nanoprobe is prepared through covalently conjugating imidazole group onto the surface of carbon dots for…”
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The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain
Published in PloS one (12-01-2017)“…Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of…”
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Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C
Published in mBio (26-10-2022)“…The maintenance of viral protein homeostasis depends on the machinery of the infected host cells, giving us an insight into the interplay between host and…”
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Ribosomal Protein L13 Participates in Innate Immune Response Induced by Foot-and-Mouth Disease Virus
Published in Frontiers in immunology (20-05-2021)“…In addition to ribosomal protein synthesis and protein translation, ribosomal proteins also participate in tumorigenesis and tumor progression, immune…”
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Identification of p72 epitopes of African swine fever virus and preliminary application
Published in Frontiers in microbiology (03-02-2023)“…African swine fever virus (ASFV) causes a highly lethal hemorrhagic viral disease (ASF) of pigs that results in serious losses in China and elsewhere. The…”
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DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication
Published in Viruses (03-09-2021)“…In cells, the contributions of DEAD-box helicases (DDXs), without which cellular life is impossible, are of utmost importance. The extremely diverse roles of…”
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Hollow mesoporous silica nanoparticles as delivery vehicle of foot‐and‐mouth disease virus‐like particles induce persistent immune responses in guinea pigs
Published in Journal of medical virology (01-06-2019)“…Foot‐and‐mouth disease (FMD) is an acute and febrile infectious disease, which can cause great economic losses. Virus‐like particles (VLPs) as an advantageous…”
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Self-Assembling E2-Based Nanoparticles Improve Vaccine Thermostability and Protective Immunity against CSFV
Published in International journal of molecular sciences (01-01-2024)“…Classical swine fever virus (CSFV) is a highly contagious pathogen causing significant economic losses in the swine industry. Conventional inactivated or…”
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15
Sec62 Regulates Endoplasmic Reticulum Stress and Autophagy Balance to Affect Foot-and-Mouth Disease Virus Replication
Published in Frontiers in cellular and infection microbiology (31-08-2021)“…Endoplasmic reticulum (ER) stress-induced autophagy is closely associated with viral infection and propagation. However, the intrinsic link between ER stress,…”
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Development and validation of a competitive ELISA based on virus-like particles of serotype Senecavirus A to detect serum antibodies
Published in AMB Express (06-01-2021)“…Virus-like particles (VLPs) are high-priority antigens with highly ordered repetitive structures, which are similar to natural viral particles. We have…”
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Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies
Published in Protein & cell (01-06-2022)Get full text
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Transcriptome Analysis of LLC-PK Cells Single or Coinfected with Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus
Published in Viruses (31-12-2023)“…Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV) are the two most prevalent swine enteric coronaviruses worldwide. They commonly…”
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Local and systemic immune responses induced by intranasal immunization with biomineralized foot-and-mouth disease virus-like particles
Published in Frontiers in microbiology (03-02-2023)“…Foot-and-mouth disease virus (FMDV) infects the host by invading mucosal epithelial cells of the respiratory or digestive tract. Therefore, establishing a…”
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Spike 1 trimer, a nanoparticle vaccine against porcine epidemic diarrhea virus induces protective immunity challenge in piglets
Published in Frontiers in microbiology (08-04-2024)“…Porcine epidemic diarrhea virus (PEDV) is considered the cause for porcine epidemic diarrhea (PED) outbreaks and hefty losses in pig farming. However, no…”
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