Search Results - "Guo Guozhen"
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Numerical simulation and analysis of effects of individual differences on the field distribution in the human brain with electromagnetic pulses
Published in Scientific reports (13-08-2021)“…The blood–brain barrier (BBB) opening induced by electromagnetic pulses (EMPs) may be a drug delivery strategy of central nervous system (CNS) diseases…”
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Effects of pulse parameters on the temperature distribution of a human head exposed to the electromagnetic pulse
Published in Scientific reports (25-11-2021)“…The presence of blood–brain barrier (BBB) is a major obstacle to effectively deliver therapeutics to the central nervous system (CNS); hence, the outcomes…”
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3
Simulation calculation of electric field distribution in the rat brain irradiated by electromagnetic pulses
Published in AIP advances (01-09-2023)“…Based on the spectrum distribution of electromagnetic pulses (EMPs), we constructed a dispersive electromagnetic model of rats with a fine division of tissues…”
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Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells
Published in Journal of pharmacological sciences (01-09-2017)“…Metformin has received increasing attention for its potential anticancer activity against certain human leukemia cells, but its effects on human…”
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Cytotoxicity of Paclitaxel Incorporated in PLGA Nanoparticles on Hypoxic Human Tumor Cells
Published in Pharmaceutical research (01-07-2009)“…Purpose The aim of this work was to prepare paclitaxel-loaded PLGA nanoparticles and determine cytotoxicity of released paclitaxel for two hypoxic human tumor…”
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HIF-1 and NDRG2 contribute to hypoxia-induced radioresistance of cervical cancer Hela cells
Published in Experimental cell research (15-07-2010)“…Hypoxia inducible factor 1 (HIF-1), the key mediator of hypoxia signaling pathways, has been shown involved in hypoxia-induced radioresistance. However, the…”
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7
Moderate white light exposure enhanced spatial memory retrieval by activating a central amygdala-involved circuit in mice
Published in Communications biology (14-04-2023)“…Light exposure can profoundly affect neurological functions and behaviors. Here, we show that short-term exposure to moderate (400 lux) white light during…”
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Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression
Published in BMC cancer (27-08-2012)“…NDRG2, a member of N-Myc downstream regulated gene family, plays some roles in cellular stress, cell differentiation and tumor suppression. We have found that…”
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Biphasic Effects of Nitric Oxide Radicals on Radiation-Induced Lethality and Chromosome Aberrations in Human Lung Cancer Cells Carrying Different p53 Gene Status
Published in International journal of radiation oncology, biology, physics (01-06-2010)“…Purpose The aim of this study was to clarify the effects of nitric oxide (NO) on radiation-induced cell killing and chromosome aberrations in two human lung…”
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Effects of 1.84 GHz radio-frequency electromagnetic field on sperm maturation in epididymis micro-environment
Published in African journal of biotechnology (01-06-2016)“…In recent years, intense interest has been drawn to the effects of radio-frequency electromagnetic field (RF-EMF) on reproduction. To explore the effects of…”
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Radio-protective effect and mechanism of 4-Acetamido-2,2,6,6- tetramethylpiperidin-1-oxyl in HUVEC cells
Published in Environmental health and preventive medicine (24-03-2017)“…To search for more effective radiation protectors with minimal toxicity, a water-soluble nitroxides Acetamido-Tempol (AA-Tempol) was evaluated for potential…”
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Paclitaxel-loaded poly(D,L-lactide-co-glycolide) nanoparticles for radiotherapy in hypoxic human tumor cells in vitro
Published in Cancer biology & therapy (01-06-2008)“…Radioresistant hypoxic cells may contribute to the failure of radiation therapy in controlling certain tumors. Some studies have suggested the radiosensitizing…”
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Increased nitric oxide synthase activity is essential for electromagnetic-pulse-induced blood–retinal barrier breakdown in vivo
Published in Brain research (06-04-2009)“…Abstract Purpose: To examine whether electromagnetic pulses (EMPs) affected the permeability of the blood–retinal barrier (BRB), gene expression of occludin…”
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Gene expression changes in the pituitary gland of rats exposed to electromagnetic pulses
Published in Biomedical and environmental sciences (01-10-2011)“…We examined alterations in the expression of tumorigenesis-related genes in the pituitary gland of rats exposed to electromagnetic pulses (EMP). The global…”
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MnSOD expression inhibited by electromagnetic pulse radiation in the rat testis
Published in Electromagnetic biology and medicine (01-12-2011)“…Male Sprague Dawley rats were exposed to EMP irradiation of 100 kV/m peak-to-peak e-field intensity and different numbers of pulses. Rat sperm samples were…”
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Radiosensitization by the Combination of SR-2508 and Paclitaxel in Hypoxic Human Tumor Cells in vitro
Published in JOURNAL OF RADIATION RESEARCH (2007)“…The two radiosensitizers SR-2508 (etanidazole) and paclitaxel (taxol) have different dose-limiting toxicities in humans. Combination of the two…”
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Nitric oxide radical-induced radioadaptation and radiosensitization are G2/M phase-dependent
Published in Journal of radiation research (2011)“…The aim of this study was to examine biological effects of nitric oxide (NO) on radiosensitivity and chromosome aberrations in different phases of the cell…”
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Nitric Oxide Radical-induced Radioadaptation and Radiosensitization Are G2/M Phase-dependent
Published in JOURNAL OF RADIATION RESEARCH (2011)“…The aim of this study was to examine biological effects of nitric oxide (NO) on radiosensitivity and chromosome aberrations in different phases of the cell…”
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19
Bright light exposure induces dynamic changes of spatial memory in nocturnal rodents
Published in Brain research bulletin (01-09-2021)“…•With longer bright light exposure, the anxiety decreased but spatial memory improved.•Long-term bright light exposure changed hippocampal dendritic spine…”
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Effects of Long-Term Exposure to L-Band High-Power Microwave on the Brain Function of Male Mice
Published in BioMed research international (2021)“…Currently, the impact of electromagnetic field (EMF) exposure on the nervous system is an increasingly arousing public concern. The present study was designed…”
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