Search Results - "Guo, Yuan‐Yuan"

SpatialDWLS: accurate deconvolution of spatial transcriptomic data by Dong, Rui, Yuan, Guo-Cheng

“…Recent development of spatial transcriptomic technologies has made it possible to characterize cellular heterogeneity with spatial information. However, the…”
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Neutrinophilic axion-like dark matter by Huang, Guo-yuan, Nath, Newton

“…The axion-like particles (ALPs) are very good candidates of the cosmological dark matter, which can exist in many extensions of the standard model (SM). The…”
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The biphasic function of microglia in ischemic stroke by Ma, Yuanyuan, Wang, Jixian, Wang, Yongting, Yang, Guo-Yuan

“…Microglia are brain resident macrophages originated from primitive progenitor cells in the yolk sac. Microglia can be activated within hours and recruited to…”
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GiniClust: detecting rare cell types from single-cell gene expression data with Gini index by Jiang, Lan, Chen, Huidong, Pinello, Luca, Yuan, Guo-Cheng

“…High-throughput single-cell technologies have great potential to discover new cell types; however, it remains challenging to detect rare cell types that are…”
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Double and multiple bangs at tau neutrino telescopes by Huang, Guo-yuan

“…In light of the exciting campaign of cosmogenic neutrino detection, we investigate the double and multiple tau bangs detectable at future tau neutrino…”
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Giotto: a toolbox for integrative analysis and visualization of spatial expression data by Dries, Ruben, Zhu, Qian, Dong, Rui, Eng, Chee-Huat Linus, Li, Huipeng, Liu, Kan, Fu, Yuntian, Zhao, Tianxiao, Sarkar, Arpan, Bao, Feng, George, Rani E, Pierson, Nico, Cai, Long, Yuan, Guo-Cheng

“…Spatial transcriptomic and proteomic technologies have provided new opportunities to investigate cells in their native microenvironment. Here we present…”
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GiniClust2: a cluster-aware, weighted ensemble clustering method for cell-type detection by Tsoucas, Daphne, Yuan, Guo-Cheng

“…Single-cell analysis is a powerful tool for dissecting the cellular composition within a tissue or organ. However, it remains difficult to detect rare and…”
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Accurate estimation of cell-type composition from gene expression data by Tsoucas, Daphne, Dong, Rui, Chen, Haide, Zhu, Qian, Guo, Guoji, Yuan, Guo-Cheng

“…The rapid development of single-cell transcriptomic technologies has helped uncover the cellular heterogeneity within cell populations. However, bulk RNA-seq…”
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Tentative sensitivity of future 0νββ-decay experiments to neutrino masses and Majorana CP phases by Huang, Guo-yuan, Zhou, Shun

“…A bstract In the near future, the neutrinoless double-beta (0 νββ ) decay experiments will hopefully reach the sensitivity of a few meV to the effective…”
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Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data by Zhu, Qian, Shah, Sheel, Dries, Ruben, Cai, Long, Yuan, Guo-Cheng

“…Combining single-cell RNA-seq with sequential single-molecule FISH defines the influence of spatial location on cell identity. How intrinsic gene-regulatory…”
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GiniClust3: a fast and memory-efficient tool for rare cell type identification by Dong, Rui, Yuan, Guo-Cheng

“…With the rapid development of single-cell RNA sequencing technology, it is possible to dissect cell-type composition at high resolution. A number of methods…”
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Endovascular aortic arch repair with chimney technique for pseudoaneurysm by Luo, Ming-Yao, Zhang, Xiong, Fang, Kun, Guo, Yuan-Yuan, Chen, Dong, Lee, Jason T, Shu, Chang

“…Aortic pseudoaneurysm is a life-threatening clinical condition, and thoracic endovascular aortic repair (TEVAR) has been reported to have a relatively…”
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Ductile 2-GPa steels with hierarchical substructure by Li, Yunjie, Yuan, Guo, Li, Linlin, Kang, Jian, Yan, Fengkai, Du, Pengju, Raabe, Dierk, Wang, Guodong

“…Mechanically strong and ductile load-carrying materials are needed in all sectors, from transportation to lightweight design to safe infrastructure. Yet, a…”
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Photoredox/Hydrogen Atom Transfer Cocatalyzed C–H Difluoroallylation of Amides, Ethers, and Alkyl Aldehydes by Guo, Yuan-Qiang, Wu, Yifan, Wang, Ruiguo, Song, Hongjian, Liu, Yuxiu, Wang, Qingmin

“…Herein, we report a method that combines hydrogen atom transfer and photoredox catalysis to achieve the dehydrogenative difluoroallylation of amides, ethers,…”
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GSCA: an integrated platform for gene set cancer analysis at genomic, pharmacogenomic and immunogenomic levels by Liu, Chun-Jie, Hu, Fei-Fei, Xie, Gui-Yan, Miao, Ya-Ru, Li, Xin-Wen, Zeng, Yan, Guo, An-Yuan

“…Abstract Cancer initiation and progression are likely caused by the dysregulation of biological pathways. Gene set analysis (GSA) could improve the…”
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GSDS 2.0: an upgraded gene feature visualization server by Hu, Bo, Jin, Jinpu, Guo, An-Yuan, Zhang, He, Luo, Jingchu, Gao, Ge

“…: Visualizing genes' structure and annotated features helps biologists to investigate their function and evolution intuitively. The Gene Structure Display…”
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lncRNASNP2: an updated database of functional SNPs and mutations in human and mouse lncRNAs by Miao, Ya-Ru, Liu, Wei, Zhang, Qiong, Guo, An-Yuan

“…Abstract Long non-coding RNAs (lncRNAs) are emerging as important regulators in different biological processes through various ways. Because the related data,…”
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Sestrin2 regulates microglia polarization through mTOR-mediated autophagic flux to attenuate inflammation during experimental brain ischemia by He, Tingting, Li, Wanlu, Song, Yaying, Li, Zongwei, Tang, Yaohui, Zhang, Zhijun, Yang, Guo-Yuan

“…Abstract Background Neuroinflammation is the major pathogenesis of cerebral ischemia. Microglia are activated and polarized to either the pro-inflammatory M1…”
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Stroke subtype-dependent synapse elimination by reactive gliosis in mice by Shi, Xiaojing, Luo, Longlong, Wang, Jixian, Shen, Hui, Li, Yongfang, Mamtilahun, Muyassar, Liu, Chang, Shi, Rubing, Lee, Joon-Hyuk, Tian, Hengli, Zhang, Zhijun, Wang, Yongting, Chung, Won-Suk, Tang, Yaohui, Yang, Guo-Yuan

“…The pathological role of reactive gliosis in CNS repair remains controversial. In this study, using murine ischemic and hemorrhagic stroke models, we…”
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Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion by Zhang, Lin-Yuan, Pan, Jiaji, Mamtilahun, Muyassar, Zhu, Yuan, Wang, Liping, Venkatesh, Ashwin, Shi, Rubing, Tu, Xuanqiang, Jin, Kunlin, Wang, Yongting, Zhang, Zhijun, Yang, Guo-Yuan

“…Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether…”
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