Search Results - "Guo, Youling"
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Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese
Published in Human molecular genetics (01-03-2012)“…In the majority of patients, epilepsy is a complex disorder with multiple susceptibility genes interacting with environmental factors. However, we understand…”
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Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study
Published in PloS one (29-03-2012)“…Hypertension is a complex disorder with high prevalence rates all over the world. We conducted the first genome-wide gene-based association scan for…”
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3
A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits
Published in PloS one (24-02-2012)“…Hypertension is caused by the interaction of environmental and genetic factors. The condition which is very common, with about 18% of the adult Hong Kong…”
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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Published in Nature communications (10-12-2018)“…The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving…”
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5
Influence of Educational Background on Untreated Dental Caries and Gingival Bleeding
Published in Alternative therapies in health and medicine (01-08-2024)“…This study aims to investigate the impact of educational background on the occurrence of untreated dental caries and gingival bleeding, shedding light on the…”
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Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
Published in Lancet neurology (01-09-2014)“…Summary Background The epilepsies are a clinically heterogeneous group of neurological disorders. Despite strong evidence for heritability, genome-wide…”
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Shared genetic basis between genetic generalized epilepsy and background electroencephalographic oscillations
Published in Epilepsia (Copenhagen) (01-07-2021)“…Objective Paroxysmal epileptiform abnormalities on electroencephalography (EEG) are the hallmark of epilepsies, but it is uncertain to what extent epilepsy and…”
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Using common genetic variants to find drugs for common epilepsies
Published in Brain communications (2021)“…Abstract Better drugs are needed for common epilepsies. Drug repurposing offers the potential of significant savings in the time and cost of developing new…”
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A Three-Stage Genome-Wide Association Study Combining Multilocus Test and Gene Expression Analysis for Young-Onset Hypertension in Taiwan Han Chinese
Published in American journal of hypertension (01-06-2014)“…BACKGROUND Although many large-scale genome-wide association studies (GWASs) have been performed, only a few studies have successfully identified replicable,…”
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10
An Improved Algorithm for Tag SNP Selection Based on Pair-Wise Linkage Disequilibrium
Published in 2008 2nd International Conference on Bioinformatics and Biomedical Engineering (2008)“…The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has recently received great attention. For…”
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Conference Proceeding Journal Article -
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Correction: A Genome-Wide Linkage and Association Scan Reveals Novel Loci for Hypertension and Blood Pressure Traits
Published in PloS one (01-06-2012)Get full text
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Correction: A Genome-Wide Linkage and Association Scan Reveals Novel Loci for Hypertension and Blood Pressure Traits
Published in PloS one (01-01-2012)Get full text
Journal Article