Search Results - "Guo, Xuejiang"

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro by Zhou, Quan, Wang, Mei, Yuan, Yan, Wang, Xuepeng, Fu, Rui, Wan, Haifeng, Xie, Mingming, Liu, Mingxi, Guo, Xuejiang, Zheng, Ying, Feng, Guihai, Shi, Qinghua, Zhao, Xiao-Yang, Sha, Jiahao, Zhou, Qi

“…In vitro generation of functional gametes is a promising approach for treating infertility, although faithful replication of meiosis has proven to be a…”
Get full text

Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation by Li, Ling, Zhu, Shuai, Shu, Wenjie, Guo, Yueshuai, Guan, Yusheng, Zeng, Juan, Wang, Haichao, Han, Longsen, Zhang, Jiaqi, Liu, Xiaohui, Li, Chunling, Hou, Xiaojing, Gao, Min, Ge, Juan, Ren, Chao, Zhang, Hao, Schedl, Tim, Guo, Xuejiang, Chen, Minjian, Wang, Qiang

“…Well-balanced and timed metabolism is essential for making a high-quality egg. However, the metabolic framework that supports oocyte development remains poorly…”
Get full text

Embryonic defects induced by maternal obesity in mice derive from Stella insufficiency in oocytes by Han, Longsen, Ren, Chao, Li, Ling, Li, Xiaoyan, Ge, Juan, Wang, Haichao, Miao, Yi-Liang, Guo, Xuejiang, Moley, Kelle H., Shu, Wenjie, Wang, Qiang

“…Maternal obesity can impair embryo development and offspring health, yet the mechanisms responsible remain poorly understood. In a high-fat diet (HFD)-based…”
Get full text

Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice by Guo, Jing, Zhang, Teng, Guo, Yueshuai, Sun, Tao, Li, Hui, Zhang, Xiaoyun, Yin, Hong, Cao, Guangyi, Yin, Yaoxue, Wang, Hao, Shi, Lanying, Guo, Xuejiang, Sha, Jiahao, Eppig, John J., Su, You-Qiang

“…MTOR (mechanistic target of rapamycin) is a widely recognized integrator of signals and pathways key for cellular metabolism, proliferation, and…”
Get full text

Loss of TIGAR Induces Oxidative Stress and Meiotic Defects in Oocytes from Obese Mice by Wang, Haichao, Cheng, Qing, Li, Xiaoyan, Hu, Feifei, Han, Longsen, Zhang, Hao, Li, Ling, Ge, Juan, Ying, Xiaoyan, Guo, Xuejiang, Wang, Qiang

“…Maternal obesity has been reported to impair oocyte quality in mice, however, the underlying mechanisms remain unclear. In the present study, by conducting a…”
Get full text

scapGNN: A graph neural network–based framework for active pathway and gene module inference from single-cell multi-omics data by Han, Xudong, Wang, Bing, Situ, Chenghao, Qi, Yaling, Zhu, Hui, Li, Yan, Guo, Xuejiang

“…Although advances in single-cell technologies have enabled the characterization of multiple omics profiles in individual cells, extracting functional and…”
Get full text

An essential role for PNLDC1 in piRNA 3＇ end trimming and male fertility in mice by Zhang, Yue, Guo, Rui, Cui, Yiqiang, Zhu, Zhiping, Zhang, Yingwen, Wu, Hao, Zheng, Bo, Yue, Qiuling, Bai, Shun, Zeng, Wentao, Guo, Xuejiang, Zhou, Zuomin, Shen, Bin, Zheng, Ke, Liu, Mingxi, Ye, Lan, Sha, Jiahao

“…Dear Editor, PIWI-interacting RNAs （piRNAs） are germ cell-specific small non-coding RNAs that are essential for silenc- ing transposable elements. Substantial…”
Get full text

LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs by Kang, Jun-Yan, Wen, Ze, Pan, Duo, Zhang, Yuhan, Li, Qing, Zhong, Ai, Yu, Xinghai, Wu, Yi-Chen, Chen, Yu, Zhang, Xiangzheng, Kou, Peng-Cheng, Geng, Junlan, Wang, Ying-Yi, Hua, Min-Min, Zong, Ruiting, Li, Biao, Shi, Hui-Juan, Li, Dangsheng, Fu, Xiang-Dong, Li, Jinsong, Nelson, David L., Guo, Xuejiang, Zhou, Yu, Gou, Lan-Tao, Huang, Ying, Liu, Mo-Fang

“…Postmeiotic spermatids use a unique strategy to coordinate gene expression with morphological transformation, in which transcription and translation take place…”
Get full text

Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes by Bai, Shun, Fu, Kaiqiang, Yin, Huiqi, Cui, Yiqiang, Yue, Qiuling, Li, Wenbo, Cheng, Le, Tan, Huanhuan, Liu, Xiaofei, Guo, Yueshuai, Zhang, Yingwen, Xie, Jie, He, Wenxiu, Wang, Yuanyuan, Feng, Hua, Xin, Changpeng, Zhang, Jinwen, Lin, Mingyan, Shen, Bin, Sun, Zheng, Guo, Xuejiang, Zheng, Ke, Ye, Lan

“…Transcription factors of the Sox protein family contain a DNA-binding HMG box and are key regulators of progenitor cell fate. Here, we report that expression…”
Get full text

Proteomic Analysis of Mouse Testis Reveals Perfluorooctanoic Acid-Induced Reproductive Dysfunction via Direct Disturbance of Testicular Steroidogenic Machinery by Zhang, Hongxia, Lu, Yin, Luo, Bin, Yan, Shengmin, Guo, Xuejiang, Dai, Jiayin

“…Perfluorooctanoic acid (PFOA) is a ubiquitous environmental pollutant suspected of being an endocrine disruptor; however, mechanisms of male reproductive…”
Get full text

PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation by Li, Zexing, Liu, Ge, Sun, Liwei, Teng, Yan, Guo, Xuejiang, Jia, Jianhang, Sha, Jiahao, Yang, Xiao, Chen, Dahua, Sun, Qinmiao

“…Stimulator of interferon genes (STING, also known as MITA and ERIS) is critical in protecting the host against DNA pathogen invasion. However, the molecular…”
Get full text

Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis by Chen, Tong, Zhang, Lin, Yao, Liangyu, Luan, Jiaochen, Zhou, Xiang, Cong, Rong, Guo, Xuejiang, Qin, Chao, Song, Ninghong

“…The widespread application of zinc oxide nanoparticles (ZnO NPs) in our daily life has initiated an enhanced awareness of their biosafety concern. An…”
Get full text

Essential role for SUN5 in anchoring sperm head to the tail by Shang, Yongliang, Zhu, Fuxi, Wang, Lina, Ouyang, Ying-Chun, Dong, Ming-Zhe, Liu, Chao, Zhao, Haichao, Cui, Xiuhong, Ma, Dongyuan, Zhang, Zhiguo, Yang, Xiaoyu, Guo, Yueshuai, Liu, Feng, Yuan, Li, Gao, Fei, Guo, Xuejiang, Sun, Qing-Yuan, Cao, Yunxia, Li, Wei

“…SUN (Sad1 and UNC84 domain containing)-domain proteins are reported to reside on the nuclear membrane playing distinct roles in nuclear dynamics. SUN5 is a new…”
Get full text

Capillary Electrophoresis–Nanoelectrospray Ionization–Selected Reaction Monitoring Mass Spectrometry via a True Sheathless Metal-Coated Emitter Interface for Robust and High-Sensitivity Sample Quantification by Guo, Xuejiang, Fillmore, Thomas L, Gao, Yuqian, Tang, Keqi

“…A new sheathless transient capillary isotachophoresis (CITP)/capillary zone electrophoresis (CZE)–MS interface, based on a commercially available capillary…”
Get full text

The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation by Wang, Min, Guo, Yueshuai, Wang, Mei, Zhou, Tao, Xue, Yuanyuan, Du, Guihua, Wei, Xiang, Wang, Jing, Qi, Lin, Zhang, Hao, Li, Lufan, Ye, Lan, Guo, Xuejiang, Wu, Xin

“…Cytokine-dependent renewal of stem cells is a fundamental requisite for tissue homeostasis and regeneration. Spermatogonial progenitor cells (SPCs) including…”
Get full text

Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types by Wang, Cheng, Gu, Yayun, Zhang, Kai, Xie, Kaipeng, Zhu, Meng, Dai, Ningbin, Jiang, Yue, Guo, Xuejiang, Liu, Mingxi, Dai, Juncheng, Wu, Linxiang, Jin, Guangfu, Ma, Hongxia, Jiang, Tao, Yin, Rong, Xia, Yankai, Liu, Li, Wang, Shouyu, Shen, Bin, Huo, Ran, Wang, Qianghu, Xu, Lin, Yang, Liuqing, Huang, Xingxu, Shen, Hongbing, Sha, Jiahao, Hu, Zhibin

“…Cancer-testis ( CT ) genes represent the similarity between the processes of spermatogenesis and tumorigenesis. It is possible that their selective expression…”
Get full text

IRESbase: A Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites by Zhao, Jian, Li, Yan, Wang, Cong, Zhang, Haotian, Zhang, Hao, Jiang, Bin, Guo, Xuejiang, Song, Xiaofeng

“…Internal ribosome entry sites (IRESs) are functional RNA elements that can directly recruit ribosomes to an internal position of the mRNA in a cap-independent…”
Get full text

TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa by Castaneda, Julio M., Hua, Rong, Miyata, Haruhiko, Oji, Asami, Guo, Yueshuai, Cheng, Yiwei, Zhou, Tao, Guo, Xuejiang, Cui, Yiqiang, Shen, Bin, Wang, Zibin, Hu, Zhibin, Zhou, Zuomin, Sha, Jiahao, Prunskaite-Hyyrylainen, Renata, Yu, Zhifeng, Ramirez-Solis, Ramiro, Ikawa, Masahito, Matzuk, Martin M., Liu, Mingxi

“…Flagella and cilia are critical cellular organelles that provide a means for cells to sense and progress through their environment. The central component of…”
Get full text

In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids by Yuan, Yan, Li, Laihua, Cheng, Qing, Diao, Feiyang, Zeng, Qiao, Yang, Xiaoyu, Wu, Yibo, Zhang, Hao, Huang, Mingqian, Chen, Junqing, Zhou, Quan, Zhu, Yunfei, Hua, Rong, Tian, Jianyu, Wang, Xin, Zhou, Zuomin, Hao, Jie, Yu, Jinjin, Hua, Dong, Liu, Jiayin, Guo, Xuejiang, Zhou, Qi, Sha, Jiahao

“…Unlike most organs that mature during the fetal period, the male reproductive system reaches maturity only at puberty with the commencement of spermatogenesis…”
Get full text

STYXL1 regulates CCT complex assembly and flagellar tubulin folding in sperm formation by Chen, Yu, Luo, Mengjiao, Tu, Haixia, Qi, Yaling, Guo, Yueshuai, Zhang, Xiangzheng, Cui, Yiqiang, Gao, Mengmeng, Zhou, Xin, Zhu, Tianyu, Zhu, Hui, Situ, Chenghao, Li, Yan, Guo, Xuejiang

“…Tubulin-based microtubule is a core component of flagella axoneme and essential for sperm motility and male fertility. Structural components of the axoneme…”
Get full text