Search Results - "Guo, Xingli"
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A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases
Published in PloS one (31-01-2014)“…Increasing evidence has indicated that long non-coding RNAs (lncRNAs) are implicated in and associated with many complex human diseases. Despite of the…”
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HPOSim: an R package for phenotypic similarity measure and enrichment analysis based on the human phenotype ontology
Published in PloS one (09-02-2015)“…Phenotypic features associated with genes and diseases play an important role in disease-related studies and most of the available methods focus solely on the…”
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Cluster correlation based method for lncRNA-disease association prediction
Published in BMC bioinformatics (11-05-2020)“…In recent years, increasing evidences have indicated that long non-coding RNAs (lncRNAs) are deeply involved in a wide range of human biological pathways. The…”
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DeepCBS: shedding light on the impact of mutations occurring at CTCF binding sites
Published in Frontiers in genetics (2024)“…CTCF-mediated chromatin loops create insulated neighborhoods that constrain promoter-enhancer interactions, serving as a unit of gene regulation. Disruption of…”
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C3: connect separate connected components to form a succinct disease module
Published in BMC bioinformatics (02-10-2020)“…Abstract Background Precise disease module is conducive to understanding the molecular mechanism of disease causation and identifying drug targets. However,…”
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Extracting Stage-Specific and Dynamic Modules Through Analyzing Multiple Networks Associated with Cancer Progression
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-03-2018)“…Determining the dynamics of pathways associated with cancer progression is critical for understanding the etiology of diseases. Advances in biological…”
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Vehicle kinematic and dynamic modeling for three-axles heavy duty vehicle
Published in Mathematical modelling and control (01-01-2022)“…Under complex conditions, the vertical, lateral and longitudinal dynamics of vehicles have obvious coupling and interaction. This paper aims to provide a…”
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Diversified Control Paths: A Significant Way Disease Genes Perturb the Human Regulatory Network
Published in PloS one (18-08-2015)“…The complexity of biological systems motivates us to use the underlying networks to provide deep understanding of disease etiology and the human diseases are…”
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CBP-JMF: An Improved Joint Matrix Tri-Factorization Method for Characterizing Complex Biological Processes of Diseases
Published in Frontiers in genetics (23-04-2021)“…Multi-omics molecules regulate complex biological processes (CBPs), which reflect the activities of various molecules in living organisms. Meanwhile, the…”
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Integrating phenotypic features and tissue-specific information to prioritize disease genes
Published in Science China. Information sciences (01-07-2016)“…Prioritization of candidate disease genes is crucial for improving medical care, and is one of the fundamental challenges in the post-genomic era. In recent…”
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A computational method based on the integration of heterogeneous networks for predicting disease-gene associations
Published in PloS one (02-09-2011)“…The identification of disease-causing genes is a fundamental challenge in human health and of great importance in improving medical care, and provides a better…”
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A New Role for LOC101928437 in Non-Syndromic Intellectual Disability: Findings from a Family-Based Association Test
Published in PloS one (19-08-2015)“…Non-syndromic intellectual disability (NSID) is mental retardation in persons of normal physical appearance who have no recognisable features apart from…”
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Residue and Dissipation Dynamics of Flusilazole in Apple and Soil
Published in Bulletin of environmental contamination and toxicology (01-03-2011)“…A simple, quick and reliable residue analytical method for flusilazole in apple and soil was developed in this study. The samples were extracted with…”
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DeepGRNCS: deep learning-based framework for jointly inferring gene regulatory networks across cell subpopulations
Published in Briefings in bioinformatics (23-05-2024)“…Inferring gene regulatory networks (GRNs) allows us to obtain a deeper understanding of cellular function and disease pathogenesis. Recent advances in…”
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Long non-coding RNAs function annotation: a global prediction method based on bi-colored networks
Published in Nucleic acids research (01-01-2013)“…More and more evidences demonstrate that the long non-coding RNAs (lncRNAs) play many key roles in diverse biological processes. There is a critical need to…”
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Excess sludge reduction using pilot-scale lysis-cryptic growth system integrated ultrasonic/alkaline disintegration and hydrolysis/acidogenesis pretreatment
Published in Bioresource technology (01-07-2012)“…► A 400m3/d lysis-cryptic growth system was operated for excess sludge reduction. ► Observed biomass yield of the pilot-scale system was 0.27kg VSS/kg COD…”
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Advances in long noncoding RNAs: identification, structure prediction and function annotation
Published in Briefings in functional genomics (01-01-2016)“…Long noncoding RNAs (lncRNAs), generally longer than 200 nucleotides and with poor protein coding potential, are usually considered collectively as a…”
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Inferring essential proteins from centrality in interconnected multilayer networks
Published in Physica A (01-11-2020)“…Computational tool for inferring essential genes and their coding essential proteins based on its topological features in biological network is crucial for…”
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lncSLdb: a resource for long non-coding RNA subcellular localization
Published in Database : the journal of biological databases and curation (01-01-2018)“…While long non-coding RNAs (lncRNAs) may play important roles in cellular function and biological process, we still know little about them. Growing evidences…”
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Genome-wide identification of the essential protein-coding genes and long non-coding RNAs for human pan-cancer
Published in Bioinformatics (01-11-2019)“…Abstract Motivation Genome-scale CRISPR/Cas9 system has been a democratized gene editing technique and widely used to investigate gene functions in some…”
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