Search Results - "Guo, Taijie"
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Modular click chemistry libraries for functional screens using a diazotizing reagent
Published in Nature (London) (01-10-2019)“…Click chemistry is a concept in which modular synthesis is used to rapidly find new molecules with desirable properties 1 . Copper( i )-catalysed azide–alkyne…”
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A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
Published in Angewandte Chemie International Edition (01-03-2018)“…Sulfuryl fluoride, SO2F2, has been found to derivatize phenols in all kinds of environments, even those in highly functional molecules. We now report that a…”
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Metal‐Free Synthesis of Functional 1‐Substituted‐1,2,3‐Triazoles from Ethenesulfonyl Fluoride and Organic Azides
Published in Angewandte Chemie International Edition (13-01-2020)“…The boom in growth of 1,4‐disubstituted triazole products, in particular, since the early 2000’s, can be largely attributed to the birth of click chemistry and…”
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KPT330 improves Cas9 precision genome- and base-editing by selectively regulating mRNA nuclear export
Published in Communications biology (17-03-2022)“…CRISPR-based genome engineering tools are associated with off-target effects that constitutively active Cas9 protein may instigate. Previous studies have…”
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Porcine Epidemic Diarrhea Virus-Induced Epidermal Growth Factor Receptor Activation Impairs the Antiviral Activity of Type I Interferon
Published in Journal of virology (15-04-2018)“…Porcine epidemic diarrhea virus (PEDV) causes acute and devastating enteric disease in suckling piglets and results in huge economic losses in the pig industry…”
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A Metabolic‐Tag‐Based Method for Assessing the Permeation of Small Molecules Across the Mycomembrane in Live Mycobacteria
Published in Angewandte Chemie International Edition (08-05-2023)“…The general lack of permeability of small molecules observed for Mycobacterium tuberculosis (Mtb) is most ascribed to its unique cell envelope. More…”
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Affinity selection of double-click triazole libraries for rapid discovery of allosteric modulators for GLP-1 receptor
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-2023)“…The recently developed double-click reaction sequence [G. Meng , , 86-89 (2019)] is expected to vastly expand the number and diversity of synthetically…”
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A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an "F-SO 2 +" Donor of Unprecedented Reactivity, Selectivity, and Scope
Published in Angewandte Chemie International Edition (01-03-2018)“…Sulfuryl fluoride, SO F , has been found to derivatize phenols in all kinds of environments, even those in highly functional molecules. We now report that a…”
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Back Cover: A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO 2 +” Donor of Unprecedented Reactivity, Selectivity, and Scope (Angew. Chem. Int. Ed. 10/2018)
Published in Angewandte Chemie International Edition (01-03-2018)Get full text
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Back Cover: A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope (Angew. Chem. Int. Ed. 10/2018)
Published in Angewandte Chemie International Edition (01-03-2018)“…A fluorosulfuryl imidazolium salt delivers an “F−SO2+” group to phenols and amines with phenomenal efficiency. In their Communication on page 2605 ff., K. B…”
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A Metabolic‐Tag‐Based Method for Assessing the Permeation of Small Molecules Across the Mycomembrane in Live Mycobacteria
Published in Angewandte Chemie (08-05-2023)“…The general lack of permeability of small molecules observed for Mycobacterium tuberculosis (Mtb) is most ascribed to its unique cell envelope. More…”
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A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO 2 +” Donor of Unprecedented Reactivity, Selectivity, and Scope
Published in Angewandte Chemie (01-03-2018)“…Abstract Sulfuryl fluoride, SO 2 F 2 , has been found to derivatize phenols in all kinds of environments, even those in highly functional molecules. We now…”
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Metal‐Free Synthesis of Functional 1‐Substituted‐1,2,3‐Triazoles from Ethenesulfonyl Fluoride and Organic Azides
Published in Angewandte Chemie (13-01-2020)“…The boom in growth of 1,4‐disubstituted triazole products, in particular, since the early 2000’s, can be largely attributed to the birth of click chemistry and…”
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Rücktitelbild: A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope (Angew. Chem. 10/2018)
Published in Angewandte Chemie (01-03-2018)“…Ein Fluorsulfurylimidazoliumsalz …… überträgt “F−SO2+"‐Einheiten hoch effizient auf Phenole und Amine. In der Zuschrift auf S. 2635 ff. beschreiben K. B…”
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A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
Published in Angewandte Chemie (01-03-2018)“…Sulfuryl fluoride, SO2F2, has been found to derivatize phenols in all kinds of environments, even those in highly functional molecules. We now report that a…”
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Novel Approaches to Access Arylfluorosulfates and Sulfamoyl Fluorides Based on Sulfur (VI) Fluoride Exchange
Published in Current protocols in chemical biology (01-06-2019)“…Sulfur (VI) fluoride exchange (SuFEx) is a new family of click chemistry reactions that relies on readily available sulfuryl fluoride (SO F ) and…”
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