Search Results - "Guo, Shenquan"

TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway by Li, Ran, Liu, Wenchao, Yin, Jian, Chen, Yunchang, Guo, Shenquan, Fan, Haiyan, Li, Xifeng, Zhang, Xin, He, Xuying, Duan, Chuanzhi

“…An acute and drastic inflammatory response characterized by the production of inflammatory mediators is followed by stroke, including SAH. Overactivation of…”
Get full text

Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch by Liu, Wenchao, Li, Ran, Yin, Jian, Guo, Shenquan, Chen, Yunchang, Fan, Haiyan, Li, Gancheng, Li, Zhenjun, Li, Xifeng, Zhang, Xin, He, Xuying, Duan, Chuanzhi

“…Activated microglia-mediated neuroinflammation has been regarded as an underlying key player in the pathogenesis of subarachnoid hemorrhage (SAH)-induced early…”
Get full text

Nrf-2 modulates excitability of hippocampal neurons by regulating ferroptosis and neuroinflammation after subarachnoid hemorrhage in rats by Fang, Dazhao, Guo, Shenquan, Wei, Boyang, Liu, Wenchao, Li, Guangxu, Li, Xifeng, Liu, Jiahui, Jin, Lei, Duan, Chuanzhi

“…Excitability of hippocampal neurons in subarachnoid hemorrhage (SAH) rats has not been well studied. The rat SAH model was applied in this study to explore the…”
Get full text

Silencing of SNHG12 Enhanced the Effectiveness of MSCs in Alleviating Ischemia/Reperfusion Injuries via the PI3K/AKT/mTOR Signaling Pathway by Li, Yuanzhi, Guo, Shenquan, Liu, Wenchao, Jin, Tao, Li, Xifeng, He, Xuying, Zhang, Xin, Su, Hengxian, Zhang, Nan, Duan, Chuanzhi

“…Previous studies have reported that the long non-coding RNA SNHG12 (lncRNA SNHG12) plays a critical role in regulating the function of mesenchymal stem cells…”
Get full text

Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome by Wei, Chengcong, Guo, Shenquan, Liu, Wenchao, Jin, Fa, Wei, Boyang, Fan, Haiyan, Su, Hengxian, Liu, Jiahui, Zhang, Nan, Fang, Dazhao, Li, Guangxu, Shu, Shixing, Li, Xifeng, He, Xuying, Zhang, Xin, Duan, Chuanzhi

“…Inflammation is typically related to dysfunction of the blood-brain barrier (BBB) that leads to early brain injury (EBI) after subarachnoid hemorrhage (SAH)…”
Get full text

Dexmedetomidine Inhibits Gasdermin D-Induced Pyroptosis via the PI3K/AKT/GSK3β Pathway to Attenuate Neuroinflammation in Early Brain Injury After Subarachnoid Hemorrhage in Rats by Wei, Boyang, Liu, Wenchao, Jin, Lei, Guo, Shenquan, Fan, Haiyan, Jin, Fa, Wei, Chengcong, Fang, Dazhao, Zhang, Xin, Su, Shixing, Duan, Chuanzhi, Li, Xifeng

“…Subarachnoid hemorrhage (SAH) is one kind of life-threatening stroke, which leads to severe brain damage. Pyroptosis plays a critical role in early brain…”
Get full text

Metformin Inhibits NLR Family Pyrin Domain Containing 3 (NLRP)-Relevant Neuroinflammation via an Adenosine-5'-Monophosphate-Activated Protein Kinase (AMPK)-Dependent Pathway to Alleviate Early Brain Injury After Subarachnoid Hemorrhage in Mice by Jin, Lei, Jin, Fa, Guo, Shenquan, Liu, Wenchao, Wei, Boyang, Fan, Haiyan, Li, Guangxu, Zhang, Xin, Su, Shixing, Li, Ran, Fang, Dazhao, Duan, Chuanzhi, Li, Xifeng

“…Neuroinflammation plays a key role in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Previous studies have shown that…”
Get full text

CDKN2BAS gene polymorphisms and the risk of intracranial aneurysm in the Chinese population by Chen, Yunchang, Li, Gancheng, Fan, Haiyan, Guo, Shenquan, Li, Ran, Yin, Jian, Zhang, Xin, Li, Xifeng, He, Xuying, Duan, Chuanzhi

“…CDKN2BAS gene polymorphisms has been shown to correlation with intracranial aneurysm(IA) in the study of foreign people. The study, the author selected the…”
Get full text

Cyclopropanation of active methylene compounds with β-alkoxycarbonyl vinylsulfonium salts by Guo, Shenquan, Zhang, Niuniu, Tang, Xiangzheng, Mao, Zhifeng, Zhang, Xuejing, Yan, Ming, Xuan, Yining

“…[Display omitted] An efficient synthesis of β-alkoxycarbonyl vinylsulfonium salts had been developed. Their reaction with indene-1,3-diones and other active…”
Get full text

A Mendelian randomisation, propensity score matching study to investigate causal association between serum homocysteine and intracranial aneurysm by Wen, Zhuohua, Feng, Xin, Tong, Xin, Peng, Chao, Xu, Anqi, Fan, Haiyan, Bi, Yiming, Liu, Wenchao, Li, Zhenjun, Guo, Shenquan, Jin, Fa, Li, Ran, Liu, Yanchao, Su, Shixing, Zhang, Xin, Li, Xifeng, He, Xuying, Liu, Aihua, Duan, Chuanzhi

“…Background and purposeRecent observational studies have reported that serum total homocysteine (tHcy) is associated with intracranial aneurysms (IAs). However,…”
Get full text

miR-96-5p alleviates cerebral ischemia-reperfusion injury in mice by inhibiting pyroptosis via downregulating caspase 1 by Jin, Fa, Jin, Lei, Wei, Boyang, Li, Xifeng, Li, Ran, Liu, Wenchao, Guo, Shenquan, Fan, Haiyan, Duan, Chuanzhi

“…Ischemic stroke is one of the leading causes of global mortality and disability. Nevertheless, successful treatment remains limited. In this study, we…”
Get full text

p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function by Cheng, Wenping, Wei, Boyang, Liu, Wenchao, Jin, Lei, Guo, Shenquan, Ding, Mingxiang, Liu, Yanchao, Fan, Haiyan, Li, Ran, Zhang, Xin, He, Xuying, Li, Xifeng, Duan, Chuanzhi

“…Neuronal apoptosis is a common pathological change in early brain injury after subarachnoid hemorrhage (SAH), and it is closely associated with neurological…”
Get full text

Optimal treatment strategy for adult patients with newly diagnosed glioblastoma: a systematic review and network meta-analysis by Jin, Lei, Guo, Shenquan, Zhang, Xin, Mo, Yunzhao, Ke, Shaowei, Duan, Chuanzhi

“…To compare the efficacy and safety of treatments based on the Stupp protocol for adult patients with newly diagnosed glioblastoma and to determine the optimal…”
Get full text

Tim-3 deteriorates neuroinflammatory and neurocyte apoptosis after subarachnoid hemorrhage through the Nrf2/HMGB1 signaling pathway in rats by Guo, Shenquan, Li, Yuanzhi, Wei, Boyang, Liu, Wenchao, Li, Ran, Cheng, Wenping, Zhang, Xin, He, Xuying, Li, Xifeng, Duan, Chuanzhi

“…Inflammation is known to play an important role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). T cell immunoglobulin and mucin domain-3…”
Get full text

TSG-6 Attenuates Oxidative Stress-Induced Early Brain Injury in Subarachnoid Hemorrhage Partly by the HO-1 and Nox2 Pathways by Li, Xifeng, Liu, Wenchao, Li, Ran, Guo, Shenquan, Fan, Haiyan, Wei, Boyang, Zhang, Xin, He, Xuying, Duan, Chuanzhi

“…•TSG-6 administration alleviated neurobehavioral deficits, decreased the BWC, and ameliorated neurons apoptosis in EBI after SAH.•TSG-6 treatment inhibited…”
Get full text

Cellular energy supply for promoting vascular remodeling of small-diameter vascular grafts: a preliminary study of a new strategy for vascular graft development by Su, Hengxian, Liu, Wenchao, Li, Xifeng, Li, Guangxu, Guo, Shenquan, Liu, Chang, Yang, Tao, Ou, Chubin, Liu, Jiahui, Li, Yuanzhi, Wei, Chengcong, Huang, Qing, Xu, Tao, Duan, Chuanzhi

“…Rapid endothelialization is extremely essential for the success of small-diameter tissue-engineered vascular graft (TEVG) (<6 mm) transplantation. However,…”
Get more information

VEGF combined with DAPT promotes tissue regeneration and remodeling in vascular grafts by Yang, Tao, Li, Guangxu, Li, Xifeng, Wei, Boyang, Su, Hengxian, Liu, Wenchao, Guo, Shenquan, Yang, Nan, Xu, Tao, Duan, Chuanzhi

“…Abstract Previous research on tissue-engineered blood vessels (TEBVs) has mainly focused on the intima or adventitia unilaterally, neglecting the equal…”
Get full text

China Intracranial Aneurysm Project (CIAP): protocol for a prospective cohort study of interventional treatment and craniotomy for unruptured aneurysms by Chen, Yunchang, Fan, Haiyan, He, Xuying, Guo, Shenquan, Li, Xifeng, He, Min, Qu, Yan, Yang, Xinjian, Zhang, Hongqi, Sun, Xiaochuan, Wang, Liqun, Wang, Zhong, Tong, Xiaoguang, Zhong, Ming, Maimaitili, Aisha, Tong, Zhiyong, Duan, Chuanzhi

“…IntroductionThere are two approaches for the treatment of intracranial aneurysm (IA): interventional therapy and craniotomy, both of which have their…”
Get full text