Search Results - "Guo, Shengchao"

Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4 by Xiao, Peng, Guo, Shengchao, Wen, Xin, He, Qing-Tao, Lin, Hui, Huang, Shen-Ming, Gou, Lu, Zhang, Chao, Yang, Zhao, Zhong, Ya-Ni, Yang, Chuan-Cheng, Li, Yu, Gong, Zheng, Tao, Xiao-Na, Yang, Zhi-Shuai, Lu, Yan, Li, Shao-Long, He, Jun-Yan, Wang, Chuanxin, Zhang, Lei, Kong, Liangliang, Sun, Jin-Peng, Yu, Xiao

“…Adhesion G protein-coupled receptors (aGPCRs) constitute an evolutionarily ancient family of receptors that often undergo autoproteolysis to produce α and β…”
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Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury by Fu, Yi, Huang, Yaqian, Yang, Zhao, Chen, Yufei, Zheng, Jingang, Mao, Chenfeng, Li, Zhiqing, Liu, Zhixin, Yu, Bing, Li, Tuoyi, Wang, Meili, Xu, Chanjuan, Zhou, Yiwei, Zhao, Guizhen, Jia, Yiting, Guo, Wei, Jia, Xin, Zhang, Tao, Li, Li, Liu, Ziyi, Guo, Shengchao, Ma, Mingliang, Zhang, Heng, Liu, Bo, Du, Junbao, Wang, Wengong, Tang, Chaoshu, Gao, Pei, Xu, Qingbo, Wang, Xian, Liu, Jianfeng, Sun, Jinpeng, Kong, Wei

“…Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling, including angiotensin II (AngII) receptor type 1 (AT1)…”
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Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology by Sun, Yujing, Zhang, Daolai, Ma, Ming-Liang, Lin, Hui, Song, Youchen, Wang, Junyan, Ma, Chuanshun, Yu, Ke, An, Wentao, Guo, Shengchao, He, Dongfang, Yang, Zhao, Xiao, Peng, Hou, Guige, Yu, Xiao, Sun, Jin-Peng

“…The adhesion GPCR ADGRG2, also known as GPR64, is a critical regulator of male fertility that maintains ion/pH homeostasis and CFTR coupling. The molecular…”
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Efficacy of Oxymatrine Plus Antiviral in the Treatment of Sepsis and Its Effect on the Levels of Endotoxin and Inflammatory Factors by Zhao, Jinglin, Wei, Qi, Guo, Shengchao, Wang, Hao, Zhao, Chao, Hu, Caihong, Liu, Cuicui, Dai, Qingchun, Wang, Rui

“…Objective. To assess the clinical efficacy of oxymatrine plus antiviral therapy in the treatment of sepsis and its effects on the levels of endotoxin and…”
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Structures of the ADGRG2–Gs complex in apo and ligand-bound forms by Lin, Hui, Xiao, Peng, Bu, Rui-Qian, Guo, Shengchao, Yang, Zhao, Yuan, Daopeng, Zhu, Zhong-Liang, Zhang, Chuan-Xin, He, Qing-Tao, Zhang, Chao, Ping, Yu-Qi, Zhao, Ru-Jia, Ma, Chuan-Shun, Liu, Chang-Hao, Zhang, Xiao-Ning, Jiang, Dan, Huang, Shaohui, Xi, Yue-Tong, Zhang, Dao-Lai, Xue, Chen-Yang, Yang, Bai-Sheng, Li, Jian-Yuan, Lin, Hao-Cheng, Zeng, Xu-Hui, Zhao, Han, Xu, Wen-Ming, Yi, Fan, Liu, Zhongmin, Sun, Jin-Peng, Yu, Xiao

“…Adhesion G protein-coupled receptors are elusive in terms of their structural information and ligands. Here, we solved the cryogenic-electron microscopy…”
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Cell active and functionally-relevant small-molecule agonists of calcitonin receptor by Zhao, Shuai, Guo, Shengchao, Yang, Chan, Gong, Zheng, Wang, Yaomin, Jia, Yingli, Jiang, Xinyu, Xu, Liwei, Shi, Li, Yu, Xiao, Sun, Jinpeng, Zhang, Yan, Chen, Xin

“…[Display omitted] •Analogues of SUN-B8155 induced different Gs or arrestin activities through CTR.•N-Hydroxyl group from the pyridone ring is required for G…”
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Structures of the ADGRG2-G s complex in apo and ligand-bound forms by Lin, Hui, Xiao, Peng, Bu, Rui-Qian, Guo, Shengchao, Yang, Zhao, Yuan, Daopeng, Zhu, Zhong-Liang, Zhang, Chuan-Xin, He, Qing-Tao, Zhang, Chao, Ping, Yu-Qi, Zhao, Ru-Jia, Ma, Chuan-Shun, Liu, Chang-Hao, Zhang, Xiao-Ning, Jiang, Dan, Huang, Shaohui, Xi, Yue-Tong, Zhang, Dao-Lai, Xue, Chen-Yang, Yang, Bai-Sheng, Li, Jian-Yuan, Lin, Hao-Cheng, Zeng, Xu-Hui, Zhao, Han, Xu, Wen-Ming, Yi, Fan, Liu, Zhongmin, Sun, Jin-Peng, Yu, Xiao

“…Adhesion G protein-coupled receptors are elusive in terms of their structural information and ligands. Here, we solved the cryogenic-electron microscopy…”
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