Search Results - "Guo, Shaodong"
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1
Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention
Published in Journal of endocrinology (01-02-2014)Get full text
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Insulin receptor substrate signaling controls cardiac energy metabolism and heart failure
Published in Journal of endocrinology (01-06-2017)“…The heart is an insulin-dependent and energy-consuming organ in which insulin and nutritional signaling integrates to the regulation of cardiac metabolism,…”
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Etiology of Metabolic Syndrome and Dietary Intervention
Published in International journal of molecular sciences (31-12-2018)“…The growing prevalence of metabolic syndrome (MetS) in the U.S. and even worldwide is becoming a serious health problem and economic burden. MetS has become a…”
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Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
Published in Cell reports (Cambridge) (05-11-2019)“…Impaired mitochondrial respiratory activity contributes to the development of insulin resistance in type 2 diabetes. Metformin, a first-line antidiabetic drug,…”
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Effect of electrolytic zero-valent iron activated sodium hypochlorite on sludge dewatering performance
Published in Water science and technology (15-02-2024)“…Using electrolytic zero-valent iron-activated sodium hypochlorite (EZVI-NaClO) to pretreat sludge, the capillary suction time (CST) was utilized to evaluate…”
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Regulation of Macronutrients in Insulin Resistance and Glucose Homeostasis during Type 2 Diabetes Mellitus
Published in Nutrients (01-11-2023)“…Insulin resistance is an important feature of metabolic syndrome and a precursor of type 2 diabetes mellitus (T2DM). Overnutrition-induced obesity is a major…”
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Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1
Published in Diabetes (New York, N.Y.) (01-02-2019)“…Premenopausal women exhibit enhanced insulin sensitivity and reduced incidence of type 2 diabetes (T2D) compared with age-matched men, but this advantage…”
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TGF-β1 Signaling Impairs Metformin Action on Glycemic Control
Published in International journal of molecular sciences (01-02-2024)“…Hyperglycemia is a hallmark of type 2 diabetes (T2D). Metformin, the first-line drug used to treat T2D, maintains blood glucose within a normal range by…”
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Insulin Signaling, Resistance, and the Metabolic Syndrome: Insights from Mouse Models to Disease Mechanisms
Published in Journal of endocrinology (08-01-2014)“…Insulin resistance is a major underlying mechanism for the “metabolic syndrome”, which is also known as insulin resistance syndrome. Metabolic syndrome is…”
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Protective Effects of Ghrelin on Fasting-Induced Muscle Atrophy in Aging Mice
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09-03-2020)“…Abstract Sarcopenia is the aging-associated progressive loss of skeletal muscle; however, the pathogenic mechanism of sarcopenia is not clear. The orexigenic…”
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Insight into the comparison of thermally and Fe(II) activated persulfate on sludge dewaterability and disintegration
Published in Water science and technology (15-09-2021)“…Abstract The effects of thermally and Fe(II) activated potassium persulfate (PPS) on sludge dewatering performance were compared systematically. Sludge…”
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Microalgal–bacterial granular sludge process for non-aerated aquaculture wastewater treatment
Published in Bioprocess and biosystems engineering (01-08-2021)“…Microalgal–bacterial granular sludge (MBGS) process has become a focal point in treating municipal wastewater. However, it remains elusive whether the emerging…”
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13
Bacterial communities of four adjacent fresh lakes at different trophic status
Published in Ecotoxicology and environmental safety (15-08-2018)“…Knowing the microbial compositions in fresh lakes is significant to explore the mechanisms of eutrophication and algal blooms. This study reported on the…”
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DPP-4 Inhibitors Improve Diabetic Wound Healing via Direct and Indirect Promotion of Epithelial-Mesenchymal Transition and Reduction of Scarring
Published in Diabetes (New York, N.Y.) (01-03-2018)“…Patients with diabetes often experience multiple disease complications. Hypoglycemic agents can have both positive and negative effects on diabetic…”
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Improvement of sludge dewaterability and disintegration efficiency using electrolytic zero-valent iron activated peroxymonosulfate
Published in Water science and technology (15-07-2021)“…Abstract Electrolysis zero-valent iron activated peroxymonosulfate (EZVI-PMS) was applied to enhance sludge dewaterability and disintegration performance…”
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Plasma Asprosin Levels Are Associated with Glucose Metabolism, Lipid, and Sex Hormone Profiles in Females with Metabolic-Related Diseases
Published in Mediators of inflammation (01-01-2018)“…Asprosin is a white adipose tissue-derived hormone that increases abnormally in mammals with insulin resistance. However, the role of asprosin in polycystic…”
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Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38α MAPK During Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-11-2013)“…Cardiac failure is a major cause of death in patients with type 2 diabetes, but the molecular mechanism that links diabetes to heart failure remains unclear…”
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Hepatic Suppression of Foxo1 and Foxo3 Causes Hypoglycemia and Hyperlipidemia in Mice
Published in Endocrinology (Philadelphia) (01-02-2012)“…Dysregulation of blood glucose and triglycerides are the major characteristics of type 2 diabetes mellitus. We sought to identify the mechanisms regulating…”
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Adsorption of Methylene Blue onto Novel Biochars Prepared from Magnolia grandiflora Linn Fallen Leaves at Three Pyrolysis Temperatures
Published in Water, air, and soil pollution (01-12-2019)“…The adsorption properties and mechanisms of methylene blue (MB) onto novel biochars produced by the fallen leaves of Magnolia grandiflora Linn (MGL), at…”
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Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
Published in Nature communications (25-07-2017)“…Diabetes and obesity are characterized by insulin resistance and chronic low-grade inflammation. An elevated plasma concentration of lipopolysaccharide (LPS)…”
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