Search Results - "Guo, Jinan"

Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing by Ma, Xiaoshi, Guo, Jinan, Liu, Kaisheng, Chen, Lipeng, Liu, Dale, Dong, Shaowei, Xia, Jinquan, Long, Qiaoyun, Yue, Yongjian, Zhao, Pan, Hu, Fengyan, Xiao, Zhangang, Pan, Xinghua, Xiao, Kefeng, Cheng, Zhiqiang, Ke, Zunfu, Chen, Zhe-Sheng, Zou, Chang

“…The highly intra-tumoral heterogeneity and complex cell origination of prostate cancer greatly limits the utility of traditional bulk RNA sequencing in finding…”
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Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer by Liu, Pengyu, Wang, Wenxuan, Wang, Fei, Fan, Jiaqi, Guo, Jinan, Wu, Tao, Lu, Dongliang, Zhou, Qingchun, Liu, Zhuohao, Wang, Yuliang, Shang, Zhiqun, Chan, Franky Leung, Yang, Wei, Li, Xin, Zhao, Shan-Chao, Zheng, Qingyou, Wang, Fei, Wu, Dinglan

“…Current diagnosis tools for prostate cancer (PCa) such as serum PSA detection and prostate biopsy cannot distinguish dormant tumors from invasive malignancies,…”
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Docetaxel suppressed cell proliferation through Smad3/HIF-1α-mediated glycolysis in prostate cancer cells by Peng, Junming, He, Zhijun, Yuan, Yeqing, Xie, Jing, Zhou, Yu, Guo, Baochun, Guo, Jinan

“…Tumor glycolysis is a critical event for tumor progression. Docetaxel is widely used as a first-line drug for chemotherapy and shown to have a survival…”
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MiR-204-3p Inhibited the Proliferation of Bladder Cancer Cells via Modulating Lactate Dehydrogenase-Mediated Glycolysis by Guo, Jinan, Zhao, Pan, Liu, Zengqin, Li, Zaishang, Yuan, Yeqing, Zhang, Xueqi, Yu, Zhou, Fang, Jiequn, Xiao, Kefeng

“…MicroRNAs (miRNAs) are endogenous non-coding RNAs that negatively regulate the expression of downstream targeted mRNAs. Increasing evidence has suggested that…”
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Case report: A collision tumor of clear cell renal cell carcinoma and clear cell papillary renal cell tumor by Lin, Yingsheng, Guo, Jinan, Li, Zaishang, Liu, Zengqin, Xie, Jing, Liu, Junxu, Jin, Hongtao, Xiao, Kefeng

“…We report the case of a 51-year-old woman who was initially hospitalized in the respiratory department with cough and fever. Urinary computed tomography (CT)…”
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The lncRNA DLX6-AS1 promoted cell proliferation, invasion, migration and epithelial-to-mesenchymal transition in bladder cancer via modulating Wnt/β-catenin signaling pathway by Guo, Jinan, Chen, Zhixin, Jiang, Hongtao, Yu, Zhou, Peng, Junming, Xie, Jing, Li, ZaiShang, Wu, Weiqing, Cheng, Zhiqiang, Xiao, Kefeng

“…Bladder cancer is the most common human urological malignancies with poor prognosis, and the pathophysiology of bladder cancer involves multi-linkages of…”
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JQ1, a BET‐bromodomain inhibitor, inhibits human cancer growth and suppresses PD‐L1 expression by Liu, Kaisheng, Zhou, Zhifan, Gao, Hengyuan, Yang, Fang, Qian, Yajun, Jin, Hongtao, Guo, Yaomin, Liu, Ying, Li, Haili, Zhang, Cheng, Guo, Jinan, Wan, Yong, Chen, Rui

“…Most traditional cytotoxic chemotherapeutic agents have poor aqueous solubility and significant toxicity. Hence, there is a need to develop molecule‐targeted…”
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Development and validation of a 25-Gene Panel urine test for prostate cancer diagnosis and potential treatment follow-up by Johnson, Heather, Guo, Jinan, Zhang, Xuhui, Zhang, Heqiu, Simoulis, Athanasios, Wu, Alan H B, Xia, Taolin, Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per-Anders, Kenner, Lukas, Feng, Xiaoyan, Zou, Chang, Xiao, Kefeng, Persson, Jenny L, Chen, Lingwu

“…Heterogeneity of prostate cancer (PCa) contributes to inaccurate cancer screening and diagnosis, unnecessary biopsies, and overtreatment. We intended to…”
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TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma by Xiao, Wenjing, Du, Nan, Huang, Taoyuan, Guo, Jinan, Mo, Xingkui, Yuan, Tao, Chen, Yong, Ye, Ting, Xu, Chunwei, Wang, Wenxian, Wang, Guoqiang, Cai, Shangli, Chen, Jing

“…TP53 has been proved to be associated with cytotoxic T-cell induced apoptosis, however, the association between TP53 and the benefit of immunotherapy in…”
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Single-cell transcriptomics reveals the ameliorative effect of rosmarinic acid on diabetic nephropathy-induced kidney injury by modulating oxidative stress and inflammation by Chen, Junhui, Zhang, Qian, Guo, Jinan, Gu, Di, Liu, Jing, Luo, Piao, Bai, Yunmeng, Chen, Jiayun, Zhang, Xinzhou, Nie, Sheng, Chen, Chunbo, Feng, Yulin, Wang, Jigang

“…Diabetic nephropathy (DN) is a severe complication of diabetes, characterized by changes in kidney structure and function. The natural product rosmarinic acid…”
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Identification of a 24-gene panel and a novel marker of PODXL2 essential for the pathological diagnosis of early prostate cancer by Ma, Xiaoshi, Chen, Lipeng, Chen, Tao, Chen, Kun, Zhang, Huirong, Huang, Kaipeng, Zheng, Han, Jin, Hongtao, Cheng, Zhiqiang, Xiao, Kefeng, Guo, Jinan

“…Precise diagnosis of early prostate cancer (PCa) is critical for preventing tumor progression. However, the diagnostic outcomes of currently used markers are…”
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Single-cell RNA sequencing reveals the effects of hederasaponin C in the treatment of diabetic nephropathy by Liu, Jing, Zhang, Qian, Zhao, Wentong, Guo, Jinan, Wong, Yin Kwan, Zhang, Chunting, Qiu, Weijin, Luo, Piao, Chen, Junhui, Li, Junmao, Li, Xiaoran, Gao, Hongwei, Yang, Shilin, Feng, Yulin, Wang, Jigang

“…There is great demand for the development of novel efficient therapeutic strategies or preventative measures to alleviate the life-threatening complications of…”
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Establishing a Urine-Based Biomarker Assay for Prostate Cancer Risk Stratification by Guo, Jinan, Liu, Dale, Zhang, Xuhui, Johnson, Heather, Feng, Xiaoyan, Zhang, Heqiu, Wu, Alan H B, Chen, Lingwu, Fang, Jiequn, Xiao, Zhangang, Xiao, Kefeng, Persson, Jenny L, Zou, Chang

“…One of the major features of prostate cancer (PCa) is its heterogeneity, which often leads to uncertainty in cancer diagnostics and unnecessary biopsies as…”
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A 23‐Gene Classifier urine test for prostate cancer prognosis by Guo, Jinan, Johnson, Heather, Zhang, Xuhui, Feng, Xiaoyan, Zhang, Heqiu, Simoulis, Athanasios, Wu, Alan HB, Xia, Taolin, Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per‐Anders, Kenner, Lukas, Chen, Lingwu, Zhong, Wanmei, Xiao, Kefeng, Persson, Jenny L., Zou, Chang

“…The patients were divided into two risk groups based on diagnosis by the 23-Gene Classifier and Kaplan-Meier survival analysis showed statistically significant…”
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Non-invasive Urine Test for Molecular Classification of Clinical Significance in Newly Diagnosed Prostate Cancer Patients by Guo, Jinan, Zhang, Xuhui, Xia, Taolin, Johnson, Heather, Feng, Xiaoyan, Simoulis, Athanasios, Wu, Alan H. B., Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per-Anders, Kenner, Lukas, Xiao, Kefeng, Zhang, Heqiu, Chen, Lingwu, Zou, Chang, Persson, Jenny L.

“…Objective: To avoid over-treatment of low-risk prostate cancer patients, it is important to identify clinically significant and insignificant cancer for…”
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Development and validation of a six-gene signature for predicting prognosis in prostate cancer patients with lymph node metastasis by Guo, Jinan, Xie, Wenzhuan, Huang, Mengli, Gao, Chan

“…Abstract only e17524 Background: Prostate cancer (PCa) patients with lymph node metastasis (LNM) always exhibit poor clinical outcomes. A gene signature that…”
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CD147 Expression Is Associated with Tumor Proliferation in Bladder Cancer via GSDMD by Xiao, Kefeng, Yuan, Qian, Huang, Jiansheng, Guo, Jinan, Jiang, Hongtao, Peng, Junming, Xie, Jing

“…Purpose. CD147, also known as BSG, is a type I transmembrane glycoprotein that belonged to immunoglobulin superfamily. Mature CD147 is an N-linked glycosylated…”
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TRIM47 promotes the Warburg effect and reduces ferroptosis in prostate cancer by FBP1 and FOXO1 by Zhao, Chubiao, Liu, Zengqin, Peng, Junming, Huang, Jiansheng, Guo, Jinan

“…Prostate cancer (PC), a malignant tumor occurring in the male prostate tissue, has a high incidence rate. In this study, we explored the role of tripartite…”
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Prognostic role of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in prostate cancer: A meta-analysis of results from multivariate analysis by Guo, Jinan, Fang, Jiequn, Huang, Xiangjiang, Liu, Yanfeng, Yuan, Yeqing, Zhang, Xueqi, Zou, Chang, Xiao, Kefeng, Wang, Jianhong

“…The prognostic role of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with prostate cancer (PCa) remains inconsistent…”
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The enhanced expression of estrogen‐related receptor α in human bladder cancer tissues and the effects of estrogen‐related receptor α knockdown on bladder cancer cells by Ye, Xinqing, Guo, Jinan, Zhang, Hongxiang, Meng, Qinggui, Ma, Yun, Lin, Rui, Yi, Xianlin, Lu, Haoyuan, Bai, Xianzhong, Cheng, Jiwen

“…Estrogen‐related receptor α (ERRα) belongs to the superfamily of nuclear orphan receptors. However, the role of ERRα in bladder cancer remains unknown. This…”
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