Search Results - "Guo, Jimmy K."
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1
Structural modularity of the XIST ribonucleoprotein complex
Published in Nature communications (02-12-2020)“…Long noncoding RNAs are thought to regulate gene expression by organizing protein complexes through unclear mechanisms. XIST controls the inactivation of an…”
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Regulatory non-coding RNAs: everything is possible, but what is important?
Published in Nature methods (01-10-2022)“…In recent years, the number of annotated noncoding RNAs (ncRNAs) and RNA-binding proteins (RBPs) has increased dramatically. The wide range of RBPs identified…”
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PRC2-RNA interactions: Viewpoint from Jimmy K. Guo, Mario R. Blanco, and Mitchell Guttman
Published in Molecular cell (03-10-2024)“…Many reported PRC2-RNA interactions have been shown to be functionally dispensable, raising questions about whether they occur in vivo. Here, we lay out…”
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Comparison of SHAPE reagents for mapping RNA structures inside living cells
Published in RNA (Cambridge) (01-02-2017)“…Recent advances in SHAPE technology have converted the classic primer extension method to next-generation sequencing platforms, allowing transcriptome-level…”
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HiChIRP reveals RNA-associated chromosome conformation
Published in Nature methods (01-06-2019)“…Modular domains of long non-coding RNAs can serve as scaffolds to bring distant regions of the linear genome into spatial proximity. Here, we present HiChIRP,…”
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