Search Results - "Guo, Jianan"

Glycolysis: an emerging regulator of osteoarthritis by Jiang, Dingming, Guo, Jianan, Liu, Yingquan, Li, Wenxin, Lu, Dezhao

“…Osteoarthritis (OA) has been a leading cause of disability in the elderly and there remains a lack of effective therapeutic approaches as the mechanisms of…”
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Divalent heavy metals and uranyl cations incorporated in calcite change its dissolution process by Zhang, Xiaohang, Guo, Jianan, Wu, Shijun, Chen, Fanrong, Yang, Yongqiang

“…Due to the high capacity of impurities in its structure, calcite is regarded as one of the most attractive minerals to trap heavy metals (HMs) and…”
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Latest advances in dual inhibitors of acetylcholinesterase and monoamine oxidase B against Alzheimer’s disease by Zou, Dajiang, Liu, Renzheng, Lv, Yangjing, Guo, Jianan, Zhang, Changjun, Xie, Yuanyuan

“…Alzheimer’s disease (AD) is a progressive brain disease characterised by progressive memory loss and cognition impairment, ultimately leading to death. There…”
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Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis by Zhu, Ji, Chen, Hang, Le, Yifei, Guo, Jianan, Liu, Zhijun, Dou, Xiaobing, Lu, Dezhao

“…Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA)…”
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Enhancing Plant Stress Tolerance: The Role of LcWRKY40 Gene in Drought and Alkaline Salt Resistance in Tobacco and Yeast by Guo, Jianan, Zhao, Yipeng, Cheng, Huihui, Yu, Ruiqiang, Gu, Baoxiang, Wang, Qiuhui, Zhang, Jitao, Li, Shenglin, Guan, Qingjie

“…, a halophytic perennial grass belonging to the Poaceae family, thrives in saline-alkali grasslands and harbors a rich repository of resistance-related genetic…”
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Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer's disease by Zhang, Changjun, Zhang, Yujia, Lv, Yangjing, Guo, Jianan, Gao, Bianbian, Lu, Yi, Zang, Anjie, Zhu, Xi, Zhou, Tao, Xie, Yuanyuan

“…Based on the multitarget-directed ligands (MTDLs) strategy, a series of chromone-hydroxypyridinone hybrids were designed, synthesised, and evaluated as…”
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Functional Study of Amorpha fruticosa WRKY20 Gene in Response to Drought Stress by Li, Danni, Gu, Baoxiang, Huang, Chunxi, Shen, Jiayi, Wang, Xin, Guo, Jianan, Yu, Ruiqiang, Mou, Sirui, Guan, Qingjie

“…The WRKY gene family in plants regulates the plant's response to drought through regulatory networks and hormone signaling. (MT859405) was cloned from ( )…”
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Lower ultra-short-term heart rate variability can predict worse mucosal healing in ulcerative colitis by Guo, Jianan, Chen, Wenguo, Zhu, Huatuo, Chen, Hongtan, Teng, Xiaodong, Xu, Guoqiang

“…Psychological stress has been proved to be a risk factor for exacerbation for ulcerative colitis (UC). However, traditional approaches of quantifying…”
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Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue by Song, Wenxin, Luo, Qi, Zhang, Yuping, Zhou, Linkang, Liu, Ye, Ma, Zhilong, Guo, Jianan, Huang, Yuedong, Cheng, Lili, Meng, Ziyi, Li, Zicheng, Zhang, Bin, Li, Siqi, Yee, Sook Wah, Fan, Hao, Li, Peng, Giacomini, Kathleen M, Chen, Ligong

“…Beiging of white adipose tissue (WAT) is a particularly appealing target for therapeutics in the treatment of metabolic diseases through norepinephrine…”
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Simulation Study on the Energy Utilization Efficiency of a Turbine Impeller Based on a Selective Laser Melting Process by Guo, Jianan, Wang, Yongqiu, Wang, Yingzan, Peng, Shitong, Wang, Fengtao

“…In this paper, a simulation model for Selective Laser Melting (SLM) technology is established to simulate the additive manufacturing process of a turbine…”
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Dual-target anti-Alzheimer's disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activity by Mi, Zhisheng, Gan, Bing, Yu, Sihang, Guo, Jianan, Zhang, Changjun, Jiang, Xiaoying, Zhou, Tao, Su, Jing, Bai, Renren, Xie, Yuanyuan

“…MAO-B leads to an increase in the levels of hydrogen peroxide and oxidative free radicals, which contribute to the aetiology of the AD. Thus, both iron ion…”
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Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease by Jiang, Xiaoying, Guo, Jianan, Zhang, Changjun, Gu, Jinping, Zhou, Tao, Bai, Renren, Xie, Yuanyuan

“…A novel class of benzamide-hydroxypyridinone (HPO) derivatives were innovatively designed, synthesised, and biologically evaluated as potential multitargeting…”
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Vegetative cell wall protein OsGP1 regulates cell wall mediated soda saline-alkali stress in rice by Zhu, Fengjin, Cheng, Huihui, Guo, Jianan, Bai, Shuomeng, Liu, Ziang, Huang, Chunxi, Shen, Jiayi, Wang, Kai, Yang, Chengjun, Guan, Qingjie

“…Plant growth and development are inhibited by the high levels of ions and pH due to soda saline-alkali soil, and the cell wall serves as a crucial barrier…”
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Monitoring Surface Water Area Changes in the Aral Sea Basin Using the Google Earth Engine Cloud Platform by Huang, Shuangyan, Chen, Xi, Ma, Xiaoting, Fang, Hui, Liu, Tie, Kurban, Alishir, Guo, Jianan, De Maeyer, Philippe, Van de Voorde, Tim

“…The surface water area and types in the Aral Sea Basin (ASB) have undergone extensive changes due to the impacts of climate change and anthropogenic…”
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Rapamycin Protects Sepsis-Induced Cognitive Impairment in Mouse Hippocampus by Enhancing Autophagy by Liu, Wenyu, Guo, Jia’nan, Mu, Jie, Tian, Linyu, Zhou, Dong

“…The purpose of this study is to test the hypothesis that the mammalian target of rapamycin (mTOR) signaling pathway might mediate neuroprotection in a mouse…”
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Oxidative stress: The core pathogenesis and mechanism of Alzheimer’s disease by Bai, Renren, Guo, Jianan, Ye, Xiang-Yang, Xie, Yuanyuan, Xie, Tian

“…As the number of patients with Alzheimer’s disease (AD) increases, it brings great suffering to their families and causes a heavy socioeconomic burden to…”
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Immobilization of cadmium by hydroxyapatite converted from microbial precipitated calcite by Wang, Maolin, Wu, Shijun, Guo, Jianan, Zhang, Xiaohang, Yang, Yongqiang, Chen, Fanrong, Zhu, Runliang

“…[Display omitted] •Microbial precipitated calcite was prepared in the absence/presence of Cd.•Calcite was converted to hydroxyapatite (HAP) under mild…”
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Tourists' negative emotions: antecedents and consequences by Kim, Jong-Hyeong, Guo, Jianan, Wang, Yisan

“…The extant literature emphasizes the influence of tourists' emotional experiences on their future behaviors. However, researchers seldom focused on negative…”
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Dynamic characteristic of rudder loop with rough revolute joint clearance by Guo, Jianan, Wang, Yingzan, Zhang, Xingwei, Cao, Sheng, Liu, Zhansheng

“…The joint clearance of rudder loop has a significant impact in achieving the high-precision attitude control of aircraft. This study proposed a novel revolute…”
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Investigation of an improved planar revolute clearance joint contact model with rough surface by Guo, Jianan, He, Peng, Liu, Zhansheng, Huang, Hongyan

“…A theoretical contact model of revolute joints with planar rough contacting surface is established in this paper. The influence of roughness is introduced in…”
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