Search Results - "Guo, Huicai"
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Perfluorooctane sulfonate promotes atherosclerosis by modulating M1 polarization of macrophages through the NF-κB pathway
Published in Ecotoxicology and environmental safety (01-01-2023)“…Perfluorooctane sulfonate (PFOS) is a widely used and distributed perfluorinated compounds and is reported to be harmful to cardiovascular health; however, the…”
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Association of co-exposure to organophosphate esters and per- and polyfluoroalkyl substances and mixture with cardiovascular-kidney-liver-metabolic biomarkers among Chinese adults
Published in Ecotoxicology and environmental safety (15-07-2024)“…Organophosphate esters (OPEs) and Per- and polyfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants with common exposure sources, leading to…”
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Association of per- and polyfluoroalkyl substances with hepatic steatosis and metabolic dysfunction-associated fatty liver disease among patients with acute coronary syndrome
Published in Ecotoxicology and environmental safety (01-10-2023)“…Etiology of hepatic steatosis and metabolic dysfunction-associated fatty liver disease (MAFLD) among acute coronary syndrome (ACS) remains unclear. Existing…”
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L-Type Calcium Channel Inhibition Contributes to the Proarrhythmic Effects of Aconitine in Human Cardiomyocytes
Published in PloS one (05-01-2017)“…Aconitine (ACO) is well-known for causing lethal ventricular tachyarrhythmias. While cardiac Na+ channel opening during repolarization has long been documented…”
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Reduction of DNA damage induced by titanium dioxide nanoparticles through Nrf2 in vitro and in vivo
Published in Journal of hazardous materials (15-11-2015)“…•Nrf2 signals were partly responsible for the DNA damage induced by Nano-TiO2.•Nrf2 loss could aggravate the DNA damage induced by Nano-TiO2.•Acquired Nrf2…”
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Effects of Sediment Types on the Distribution and Diversity of Plant Communities in the Poyang Lake Wetlands
Published in Diversity (Basel) (01-06-2022)“…At small scales, sedimentary deposition types mediate hydrological changes to drive wetland vegetation distribution patterns and species diversity. To examine…”
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Association between per- and polyfluoroalkyl substances and risk of hypertension: a systematic review and meta-analysis
Published in Frontiers in public health (02-08-2023)“…Existing evidence indicates that exposure to per- and polyfluoroalkyl substances (PFASs) may increase the risk of hypertension, but the findings are…”
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Na+/K+-ATPase-mediated signal transduction and Na+/K+-ATPase regulation
Published in Fundamental & clinical pharmacology (01-12-2008)“…A number of studies suggest that Na+/K+‐ATPase in caveolae interacts with neighboring membrane proteins and organizes cytosolic cascades of signaling proteins…”
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The toxic influence of paraquat on hippocampus of mice: Involvement of oxidative stress
Published in Neurotoxicology (Park Forest South) (01-06-2010)“…Environmental paraquat (PQ) exposure has been suggested to be a potential risk factor for neurodegenerative disorders such as Parkinson's disease (PD). The…”
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Na+/K+-ATPase inhibition upregulates NMDA-evoked currents in rat hippocampal CA1 pyramidal neurons
Published in Fundamental & clinical pharmacology (01-08-2012)“…Na+/K+‐ATPase and N‐methyl‐d‐aspartate (NMDA) receptor in hippocampus play very important roles in the regulation of learning and memory. Here, we showed that…”
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Correlation analysis between per-fluoroalkyl and poly-fluoroalkyl substances exposure and depressive symptoms in adults: NHANES 2005–2018
Published in The Science of the total environment (01-01-2024)“…Excessive exposure to per and poly-fluoroalkyl compounds (PFAS) can lead to various negative health effects. However, there's a lack of research studying the…”
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Per- and polyfluoroalkyl substances and the associated thyroid cancer risk: A case-control study in China
Published in Chemosphere (Oxford) (01-10-2023)“…The role of perfluoroalkyl and polyfluoroalkyl substances (PFAS) as thyroid carcinogens is unclear. Therefore, we intended to identify associations between…”
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Hippocampal Proteomics Reveals the Role of Glutamatergic Synapse Activation in the Depression Induced by Perfluorooctane Sulfonate
Published in Journal of agricultural and food chemistry (24-05-2023)“…Perfluorooctane sulfonate (PFOS), a new type of persistent organic pollutant in the environment of water, has drawn significant attention in recent years due…”
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Legacy and alternative per- and polyfluoroalkyl substances spatiotemporal distribution in China: Human exposure, environmental media, and risk assessment
Published in Journal of hazardous materials (05-12-2024)“…In recent decades, China's rapid development has led to significant environmental pollution from the widespread use of chemical products. Per- and…”
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SAP130 mediates crosstalk between hepatocyte ferroptosis and M1 macrophage polarization in PFOS-induced hepatotoxicity
Published in The Science of the total environment (15-11-2024)“…Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant widely utilized in industrial manufacturing and daily life, leading to significant…”
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λ3‑Iodane/Lewis Acid Mediated Intramolecular Cross-Nucleophile Coupling of β‑Amino Acrylates: Chemodivergent Syntheses of Indole Alkaloidal Frameworks
Published in Organic letters (29-07-2022)“…Herein, we report an unprecedented intramolecular cross-nucleophile coupling strategy of indole tethered β-amino acrylates using a catalyst system combining…”
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Association of exposure to perfluoroalkyl substances and risk of the acute coronary syndrome: A case-control study in Shijiazhuang Hebei Province
Published in Chemosphere (Oxford) (01-02-2023)“…Exposures to perfluoroalkyl substances (PFAS) have been reported to increase the risk of atherosclerosis. Therefore, PFAS exposure may be linked to the risk of…”
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Associations between co-exposure to per- and polyfluoroalkyl substances and organophosphate esters and erythrogram in Chinese adults
Published in Chemosphere (Oxford) (01-08-2024)“…Erythrogram, despite its prevalent use in assessing red blood cell (RBC) disorders and can be utilized to evaluate various diseases, still lacks evidence…”
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Angiotoxic effects of chlorinated polyfluorinated ether sulfonate, a novel perfluorooctane sulfonate substitute, in vivo and in vitro
Published in Journal of hazardous materials (05-05-2024)“…Chlorinated polyfluorinated ether sulfonate (Cl-PFESA), a substitute for perfluorooctane sulfonate (PFOS), has been widely used in the Chinese electroplating…”
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