Search Results - "Guo, Huatao"

A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution by Zhang, Xing, Guo, Huatao, Jin, Lei, Czornyj, Elizabeth, Hodes, Asher, Hui, Wong H, Nieh, Angela W, Miller, Jeff F, Zhou, Z Hong

“…Bacteriophage BPP-1 infects and kills Bordetella species that cause whooping cough. Its diversity-generating retroelement (DGR) provides a naturally occurring…”
Get full text

Dual PI3K/mTOR inhibitor NVP-BEZ235-induced apoptosis of hepatocellular carcinoma cell lines is enhanced by inhibitors of autophagy by CHANG, ZHEXING, SHI, GUANG, JIN, JIQIANG, GUO, HUATAO, GUO, XUEFENG, LUO, FANGYUE, SONG, YUGUO, JIA, XIAOJING

“…Dysregulation of the phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling has been found in several types of human cancer,…”
Get full text

Surface display of a massively variable lipoprotein by a Legionella diversity-generating retroelement by Arambula, Diego, Wong, Wenge, Medhekar, Bob A., Guo, Huatao, Gingery, Mari, Czornyj, Elizabeth, Liu, Minghsun, Dey, Sanghamitra, Ghosh, Partho, Miller, Jeff F.

“…Diversity-generating retroelements (DGRs) are a unique family of retroelements that confer selective advantages to their hosts by facilitating localized DNA…”
Get full text

Efficient transposon mutagenesis mediated by an IPTG-controlled conditional suicide plasmid by Naorem, Santa S, Han, Jin, Zhang, Stephanie Y, Zhang, Junyi, Graham, Lindsey B, Song, Angelou, Smith, Cameron V, Rashid, Fariha, Guo, Huatao

“…Transposon mutagenesis is highly valuable for bacterial genetic and genomic studies. The transposons are usually delivered into host cells through conjugation…”
Get full text

Target site recognition by a diversity-generating retroelement by Guo, Huatao, Tse, Longping V, Nieh, Angela W, Czornyj, Elizabeth, Williams, Steven, Oukil, Sabrina, Liu, Vincent B, Miller, Jeff F

“…Diversity-generating retroelements (DGRs) are in vivo sequence diversification machines that are widely distributed in bacterial, phage, and plasmid genomes…”
Get full text

Group II introns as controllable gene targeting vectors for genetic manipulation of bacteria by Lambowitz, Alan M, Karberg, Michael, Guo, Huatao, Zhong, Jin, Coon, Robert, Perutka, Jiri

“…Mobile group II introns can be retargeted to insert into virtually any desired DNA target. Here we show that retargeted group II introns can be used for highly…”
Get full text

Group II Introns Designed to Insert into Therapeutically Relevant DNA Target Sites in Human Cells by Guo, Huatao, Karberg, Michael, Long, Meredith, Jones, J. P., Sullenger, Bruce, Lambowitz, Alan M.

“…Mobile group II intron RNAs insert directly into DNA target sites and are then reverse-transcribed into genomic DNA by the associated intron-encoded protein…”
Get full text

Correction: A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 Å resolution by Zhang, Xing, Guo, Huatao, Jin, Lei, Czornyj, Elizabeth, Hodes, Asher, Hui, Wong H, Nieh, Angela W, Miller, Jeff F, Zhou, Z Hong

Get full text

Group II intron mobility occurs by target DNA-primed reverse transcription by Zimmerly, Steven, Guo, Huatao, Perlman, Philip S., Lambowltz, Alan M.

“…Mobile group II introns encode reverse transcriptases and insert site specifically into intronless alleles (homing). Here, in vitro experiments show that…”
Get full text

A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility by Zimmerly, Steven, Guo, Huatao, Eskest, Robert, Yang, Jian, Perlman, Philip S., Lambowitz, Alan M.

“…The mobility (homing) of the yeast mitochondrial DNA group II intron al2 occurs via target DNA-primed reverse transcription at a double-strand break in the…”
Get full text

Salidroside attenuates oxidized low‑density lipoprotein‑induced endothelial cell injury via promotion of the AMPK/SIRT1 pathway by Zhao, Dongming, Sun, Xinyi, Lv, Shujie, Sun, Miying, Guo, Huatao, Zhai, Yujia, Wang, Zhi, Dai, Peng, Zheng, Lina, Ye, Mingzhe, Wang, Xinpeng

“…Oxidized low-density lipoprotein (ox-LDL)-induced endothelial damage contributes to the initiation and pathogenesis of atherosclerosis. Salidroside can…”
Get full text

Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey by Wu, Li, Gingery, Mari, Abebe, Michael, Arambula, Diego, Czornyj, Elizabeth, Handa, Sumit, Khan, Hamza, Liu, Minghsun, Pohlschroder, Mechthild, Shaw, Kharissa L, Du, Amy, Guo, Huatao, Ghosh, Partho, Miller, Jeff F, Zimmerly, Steven

“…Abstract Diversity-generating retroelements (DGRs) are novel genetic elements that use reverse transcription to generate vast numbers of sequence variants in…”
Get full text

DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA by Naorem, Santa S., Han, Jin, Wang, Shufang, Lee, William R., Heng, Xiao, Miller, Jeff F., Guo, Huatao

“…Diversity-generating retroelements (DGRs) are molecular evolution machines that facilitate microbial adaptation to environmental changes. Hypervariation occurs…”
Get full text

Diversity-generating Retroelements in Phage and Bacterial Genomes by Guo, Huatao, Arambula, Diego, Ghosh, Partho, Miller, Jeff F

“…Diversity-generating retroelements (DGRs) are DNA diversification machines found in diverse bacterial and bacteriophage genomes that accelerate the evolution…”
Get more information

Value of the relationship with plasma NT-proBNP and heart function in diagnosis of cardiac insufficiency by Guo Huatao, Xu Lihua

“…Objective to investigate the plasma NT-proBNP in value in early diagnosis of aged patients with diastolic heart failure. 26 cases of cardiac function in normal…”
Get full text

Structure of the Essential Diversity-Generating Retroelement Protein bAvd and Its Functionally Important Interaction with Reverse Transcriptase by Alayyoubi, Maher, Guo, Huatao, Dey, Sanghamitra, Golnazarian, Talin, Brooks, Garrett A., Rong, Andrew, Miller, Jeffery F., Ghosh, Partho

“…Diversity-generating retroelements (DGRs) are the only known source of massive protein sequence variation in prokaryotes. These elements transfer coding…”
Get full text

Serum ferritin and folate, but not uric acid, associate with coronary heart disease in a northern Chinese population by Xu Lihua, Guo Huatao, Lv Shujie

“…Background Increased serum ferritin and uric acid, and decreased folate may be candidate risk factors for coronary heart disease (CHD). The relation between…”
Get full text

Cohort study on hypertension prevalence in certain rural area of Jilin province by Xu Lihua, Sun Miying, Guo Huatao, Qu Cuizhu

“…Analysis and investigation on hypertension prevalence and changing trend among some rural population in Jilin province to determine the major risk factors and…”
Get full text

Diversity-Generating Retroelement Homing Regenerates Target Sequences for Repeated Rounds of Codon Rewriting and Protein Diversification by Guo, Huatao, Tse, Longping V., Barbalat, Roman, Sivaamnuaiphorn, Sameer, Xu, Min, Doulatov, Sergei, Miller, Jeff F.

“…Diversity-generating retroelements (DGRs) introduce vast amounts of sequence diversity into target genes. During mutagenic homing, adenine residues are…”
Get full text

Target Site Recognition by a Diversity-Generating Retroelement: e1002414 by Guo, Huatao, Tse, Longping V, Nieh, Angela W, Czornyj, Elizabeth, Williams, Steven, Oukil, Sabrina, Liu, Vincent B, Miller, Jeff F

“…Diversity-generating retroelements (DGRs) are in vivo sequence diversification machines that are widely distributed in bacterial, phage, and plasmid genomes…”
Get full text