Search Results - "Guo, Haitao"

Hepatitis B virus cccDNA: Formation, regulation and therapeutic potential by Xia, Yuchen, Guo, Haitao

“…Hepatitis B virus (HBV) infection remains a major public health concern worldwide with about 257 million individuals chronically infected. Current therapies…”
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Inflammasomes: mechanism of action, role in disease, and therapeutics by Guo, Haitao, Callaway, Justin B, Ting, Jenny P-Y

“…The inflammasomes are innate immune system receptors and sensors that regulate the activation of caspase-1 and induce inflammation in response to infectious…”
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Omicron variant (B.1.1.529) of SARS‐CoV‐2, a global urgent public health alert by Gao, Shou‐Jiang, Guo, Haitao, Luo, Guangxiang

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NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes by Freeman, Leslie, Guo, Haitao, David, Clément N, Brickey, W June, Jha, Sushmita, Ting, Jenny P-Y

“…Inflammation in the brain accompanies several high-impact neurological diseases including multiple sclerosis (MS), stroke, and Alzheimer's disease…”
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Epigenetic regulation of hepatitis B virus covalently closed circular DNA: Implications for epigenetic therapy against chronic hepatitis B by Hong, Xupeng, Kim, Elena S., Guo, Haitao

“…Hepatitis B virus (HBV) infection represents a significant public health burden worldwide. Although current therapeutics manage to control the disease…”
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Serum Hepatitis B Virus RNA: A New Potential Biomarker for Chronic Hepatitis B Virus Infection by Liu, Shi, Zhou, Bin, Valdes, Juan D., Sun, Jian, Guo, Haitao

“…Chronic hepatitis B infection is one of the major etiological causes of liver failure, cirrhosis, and hepatocellular carcinoma (HCC) worldwide. This condition…”
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Metabolism and function of hepatitis B virus cccDNA: Implications for the development of cccDNA-targeting antiviral therapeutics by Guo, Ju-Tao, Guo, Haitao

“…•Hepatitis B virus (HBV) persistence relies on the stable maintenance and proper functioning of cccDNA.•cccDNA is synthesized from viral genomic DNA of the…”
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Movement Estimation Using Soft Sensors Based on Bi-LSTM and Two-Layer LSTM for Human Motion Capture by Guo, Haitao, Sung, Yunsick

“…The importance of estimating human movement has increased in the field of human motion capture. HTC VIVE is a popular device that provides a convenient way of…”
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An Efficient and Lightweight Convolutional Neural Network for Remote Sensing Image Scene Classification by Yu, Donghang, Xu, Qing, Guo, Haitao, Zhao, Chuan, Lin, Yuzhun, Li, Daoji

“…Classifying remote sensing images is vital for interpreting image content. Presently, remote sensing image scene classification methods using convolutional…”
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SMNet: Symmetric Multi-Task Network for Semantic Change Detection in Remote Sensing Images Based on CNN and Transformer by Niu, Yiting, Guo, Haitao, Lu, Jun, Ding, Lei, Yu, Donghang

“…Deep learning has achieved great success in remote sensing image change detection (CD). However, most methods focus only on the changed regions of images and…”
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Research on the application of big data visualization technology in urban road congestion by Guo, Haitao, Xu, Lunhui

“…In order to improve the effect of urban road congestion analysis, this paper aims to study the mechanism of traffic congestion diffusion under the condition…”
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Rapid Turnover of Hepatitis B Virus Covalently Closed Circular DNA Indicated by Monitoring Emergence and Reversion of Signature‐Mutation in Treated Chronic Hepatitis B Patients by Huang, Qi, Zhou, Bin, Cai, Dawei, Zong, Yuhua, Wu, Yaobo, Liu, Shi, Mercier, Alexandre, Guo, Haitao, Hou, Jinlin, Colonno, Richard, Sun, Jian

“…Background and Aims Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) plays a pivotal role in the establishment and persistence of HBV infection…”
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Host functions used by hepatitis B virus to complete its life cycle: Implications for developing host-targeting agents to treat chronic hepatitis B by Mitra, Bidisha, Thapa, Roshan J., Guo, Haitao, Block, Timothy M.

“…Similar to other mammalian viruses, the life cycle of hepatitis B virus (HBV) is heavily dependent upon and regulated by cellular (host) functions. These…”
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Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion by Zang, Ruochen, Case, James Brett, Yutuc, Eylan, Ma, Xiucui, Shen, Sheng, Castro, Maria Florencia Gomez, Liu, Zhuoming, Zeng, Qiru, Zhao, Haiyan, Son, Juhee, Rothlauf, Paul W., Kreutzberger, Alex J. B., Hou, Gaopeng, Zhang, Hu, Bose, Sayantan, Wang, Xin, Vahey, Michael D., Mani, Kartik, Griffiths, William J., Kirchhausen, Tom, Fremont, Daved H., Guo, Haitao, Diwan, Abhinav, Wang, Yuqin, Diamond, Michael S., Whelan, Sean P. J., Ding, Siyuan

“…Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-stimulated gene that shows broad antiviral activities against a wide range of enveloped viruses…”
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Hepatitis B Virus Precore Protein p22 Inhibits Alpha Interferon Signaling by Blocking STAT Nuclear Translocation by Mitra, Bidisha, Wang, Jinyu, Kim, Elena S, Mao, Richeng, Dong, Minhui, Liu, Yuanjie, Zhang, Jiming, Guo, Haitao

“…Antagonism of host immune defenses against hepatitis B virus (HBV) infection by the viral proteins is speculated to cause HBV persistence and the development…”
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Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication by Guo, Haitao, Wang, Qi, Ghneim, Khader, Wang, Li, Rampanelli, Elena, Holley-Guthrie, Elizabeth, Cheng, Liang, Garrido, Carolina, Margolis, David M., Eller, Leigh A., Robb, Merlin L., Sekaly, Rafick-Pierre, Chen, Xian, Su, Lishan, Ting, Jenny P.-Y.

“…Individuals infected with human immunodeficiency virus type-1 (HIV-1) show metabolic alterations of CD4 + T cells through unclear mechanisms with undefined…”
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Elastic, Conductive, Polymeric Hydrogels and Sponges by Lu, Yun, He, Weina, Cao, Tai, Guo, Haitao, Zhang, Yongyi, Li, Qingwen, Shao, Ziqiang, Cui, Yulin, Zhang, Xuetong

“…As a result of inherent rigidity of the conjugated macromolecular chains resulted from the delocalized π-electron system along the polymer backbone, it has…”
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Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA by Kim, Elena S, Zhou, Jun, Zhang, Hu, Marchetti, Alexander, van de Klundert, Maarten, Cai, Dawei, Yu, Xiaoyang, Mitra, Bidisha, Liu, Yuanjie, Wang, Mu, Protzer, Ulrike, Guo, Haitao

“…Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA), serving as the viral persistence form and transcription template of HBV infection, hijacks…”
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The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation by Long, Quanxin, Yan, Ran, Hu, Jieli, Cai, Dawei, Mitra, Bidisha, Kim, Elena S, Marchetti, Alexander, Zhang, Hu, Wang, Soujuan, Liu, Yuanjie, Huang, Ailong, Guo, Haitao

“…Hepadnavirus covalently closed circular (ccc) DNA is the bona fide viral transcription template, which plays a pivotal role in viral infection and persistence…”
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TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination by Deng, Meng, Tam, Jason W., Wang, Lufei, Liang, Kaixin, Li, Sirui, Zhang, Lu, Guo, Haitao, Luo, Xiaobo, Zhang, Yang, Petrucelli, Alex, Davis, Beckley K., Conti, Brian J., June Brickey, W., Ko, Ching-Chang, Lei, Yu L., Sun, Shaocong, Ting, Jenny P. -Y.

“…Innate immunity to nucleic acids forms the backbone for anti-viral immunity and several inflammatory diseases. Upon sensing cytosolic viral RNA, retinoic…”
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