Search Results - "Guo, Gongbo"

HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation by Chia, Lionel, Wang, Bowen, Kim, Jung-Hyun, Luo, Li Z, Shuai, Shuai, Herrera, Iliana, Chen, Sophia Y, Li, Liping, Xian, Lingling, Huso, Tait, Heydarian, Mohammad, Reddy, Karen, Sung, Woo Jung, Ishiyama, Shun, Guo, Gongbo, Jaffee, Elizabeth, Zheng, Lei, Cope, Leslie M, Gabrielson, Kathy, Wood, Laura, Resar, Linda

“…High mobility group A1 (HMGA1) chromatin regulators are upregulated in diverse tumors where they portend adverse outcomes, although how they function in cancer…”
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Synphilin-1 Interacts with AMPK and Increases AMPK Phosphorylation by Li, Tianxia, Liu, Jingnan, Guo, Gongbo, Ning, Bo, Li, Xueping, Zhu, Guangjing, Yang, Dejun, Moran, Timothy H, Smith, Wanli W

“…A role for the cytoplasmic protein synphilin-1 in regulating energy balance has been demonstrated recently. Expression of synphilin-1 increases ATP levels in…”
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Transmembrane Protein 230 Mediates a Poly(ADP-ribose) Polymerase-1-Linked Apoptosis by Wang, Xiaobo, Wu, Tengteng, Zhang, Jinru, Guo, Gongbo, He, XiaoFei, Pei, Zhong, Liu, Zhaohui, Liu, Chun-feng, Ross, Christopher A., Smith, Wanli W.

“…Mutations in TMEM230 (transmembrane protein 230) gene suggest to be associated with the autosomal dominant Parkinson’s disease with typical movement disorders…”
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Single-stranded DNA with internal base modifications mediates highly efficient knock-in in primary cells using CRISPR-Cas9 by Kanke, Karen L, Rayner, Rachael E, Bozik, Jack, Abel, Eli, Venugopalan, Aparna, Suu, Ma, Nouri, Reza, Stack, Jacob T, Guo, Gongbo, Vetter, Tatyana A, Cormet-Boyaka, Estelle, Hester, Mark E, Vaidyanathan, Sriram

“…Single-stranded DNA (ssDNA) templates along with Cas9 have been used for knocking-in exogenous sequences in the genome but suffer from low efficiency. Here, we…”
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Mutant-TMEM230-induced neurodegeneration and impaired axonal mitochondrial transport by Wang, Xiaobo, Guo, Gongbo, Zhang, Jinru, Aebez, Nicolas, Liu, Zhaohui, Liu, Chun-Feng, Ross, Christopher A, Smith, Wanli W

“…Parkinson's disease (PD) is a neurodegenerative disease with movement disorders including resting tremor, rigidity, bradykinesia and postural instability…”
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AMPK signaling mediates synphilin-1-induced hyperphagia and obesity in Drosophila by Liu, Jingnan, Wang, Xiaobo, Ma, Rui, Li, Tianxia, Guo, Gongbo, Ning, Bo, Moran, Timothy H, Smith, Wanli W

“…Expression of synphilin-1 in neurons induces hyperphagia and obesity in a model. However, the molecular pathways underlying synphilin-1-linked obesity remain…”
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Cerebral organoids containing an AUTS2 missense variant model microcephaly by Fair, Summer R, Schwind, Wesley, Julian, Dominic L, Biel, Alecia, Guo, Gongbo, Rutherford, Ryan, Ramadesikan, Swetha, Westfall, Jesse, Miller, Katherine E, Kararoudi, Meisam Naeimi, Hickey, Scott E, Mosher, Theresa Mihalic, McBride, Kim L, Neinast, Reid, Fitch, James, Lee, Dean A, White, Peter, Wilson, Richard K, Bedrosian, Tracy A, Koboldt, Daniel C, Hester, Mark E

“…Variants in the AUTS2 gene are associated with a broad spectrum of neurological conditions characterized by intellectual disability, microcephaly, and…”
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GTP‐binding inhibitors increase LRRK2‐linked ubiquitination and Lewy body‐like inclusions by Thomas, Joseph M., Wang, Xiaobo, Guo, Gongbo, Li, Tianxia, Dai, Bingling, Nucifora, Leslie G., Nucifora, Frederick C., Liu, Zhaohui, Xue, Fengtian, Liu, Chunfeng, Ross, Christopher A., Smith, Wanli W.

“…Parkinson's disease (PD) is one of the most common movement disorders with loss of dopaminergic neurons and the presence of Lewy bodies in certain brain areas…”
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Mutant G2019S-LRRK2 Induces Abnormalities in Arteriolar Cerebral Blood Volume in Mouse Brains: An MRI Study by Ning, Bo, Guo, Gongbo, Gu, Chunming, Xu, Jiadi, Bibic, Adnan, He, Xiaofei, Liu, Hongshuai, Chen, Lin, Wei, Zhiliang, Duan, Wenzhen, Liu, Peiying, Lu, Hanzhang, van Zijl, Peter C M, Ross, Christopher A, Smith, Wanli, Hua, Jun

“…Parkinson's disease (PD) is the second most common neurodegenerative disease and the most common movement disorder characterized by motor impairments resulting…”
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AMPK signaling mediates synphilin-1-induced hyperphagia and obesity in drosophila by Liu, Jingnan, Wang, Xiaobo, Ma, Rui, Li, Tianxia, Guo, Gongbo, Ning, Bo, Moran, Timothy H, Smith, Wanli W

“…Expression of synphilin-1 in neurons induces hyperphagia and obesity in a Drosophila model. However, the molecular pathways underlying synphilin-1-linked…”
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