Search Results - "Guo, Genglin"
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Identification of a phage-derived depolymerase specific for KL64 capsule of Klebsiella pneumoniae and its anti-biofilm effect
Published in Virus genes (01-10-2021)“…The increasing prevalence of Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a serious threat to global health. Phages and phage-derived enzymes gained…”
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Genomic characterization of Streptococcus parasuis, a close relative of Streptococcus suis and also a potential opportunistic zoonotic pathogen
Published in BMC genomics (25-06-2022)“…Abstract Streptococcus parasuis ( S. parasuis ) is a close relative of Streptococcus suis ( S. suis ), composed of former members of S. suis serotypes 20, 22…”
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An Escherichia coli isolate from hospital sewage carries blaNDM-1 and blaoxa-10
Published in Archives of microbiology (01-09-2021)“…Carbapenems, as the “last line of defense” against Gram-negative bacteria, are increasingly being challenged by drug-resistant bacteria, especially…”
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Therapeutic efficacy of a K5-specific phage and depolymerase against Klebsiella pneumoniae in a mouse model of infection
Published in Veterinary research (Paris) (07-05-2024)“…Klebsiella pneumoniae has become one of the most intractable gram-negative pathogens infecting humans and animals due to its severe antibiotic resistance…”
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Identification of novel pig and human immunoglobulin G-binding proteins and characterization of the binding regions of enolase from Streptococcus suis serotype 2
Published in AMB Express (01-06-2020)“…Streptococcus suis , a major emerging pathogen in swine and humans, expresses immunoglobulin G (IgG)-binding proteins (IBPs), which contribute to the ability…”
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Molecular characterization of invasive Streptococcus pneumoniae clinical isolates from a tertiary children’s hospital in eastern China
Published in Microbiology spectrum (01-10-2023)“…ABSTRACT Streptococcus pneumoniae is a common opportunistic pathogen that causes invasive pneumococcal disease (IPD), especially in children. This study aimed…”
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The biological role of MutT in the pathogenesis of the zoonotic pathogen Streptococcus suis serotype 2
Published in Virulence (01-12-2021)“…Streptococcus suis (S. suis) is an important rising pathogen that causes serious diseases in humans and pigs. Although some putative virulence factors of S…”
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Combing Immunoinformatics with Pangenome Analysis To Design a Multiepitope Subunit Vaccine against Klebsiella pneumoniae K1, K2, K47, and K64
Published in Microbiology spectrum (31-08-2022)“…Klebsiella pneumoniae is an opportunistic Gram-negative bacterium that has become a leading causative agent of nosocomial infections, mainly infecting patients…”
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Whole-genome analyses of APEC carrying mcr-1 in some coastal areas of China from 2019 to 2020
Published in Journal of global antimicrobial resistance. (01-09-2022)“…•In this study, 24 mcr-1-positive avian pathogenic Escherichia coli (APEC) were detected from 493 APEC isolated from waterfowl in some coastal areas of…”
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Development of an in silico serotyping database of Vibrio harveyi by identification and comparison of O-antigen encoding loci
Published in Aquaculture (15-12-2024)“…Vibrio harveyi is an important pathogen for aquatic fish and invertebrates, that can lead to significant economic losses in the aquaculture industry. Rapid and…”
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Promising potential of machine learning-assisted MALDI-TOF MS as an effective detector for Streptococcus suis serotype 2 and virulence thereof
Published in Applied and environmental microbiology (29-11-2023)“…To the best of our knowledge, this study reveals a strong correlation between mass spectra pattern and virulence phenotype among for the first time. In order…”
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Contribution of nadR to the cell growth and virulence of Streptococcus suis serotype 2
Published in Veterinary microbiology (01-01-2024)“…Streptococcus suis serotype 2 (SS2) has been reported to be a highly invasive pathogen in swine and a zoonotic agent for humans. Although many bacterial…”
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ICEHpsaHPS7, a Novel Multiple Drug Resistance Integrative Conjugative Element in Glaesserella parasuis
Published in Antimicrobial agents and chemotherapy (20-01-2021)“…Integrative conjugative elements (ICEs) are a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in ( ) We…”
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Identification of Subunits for Novel Universal Vaccines against Three Predominant Serogroups and the Emerging O145 among Avian Pathogenic Escherichia coli by Pan-RV Pipeline
Published in Applied and environmental microbiology (31-01-2023)“…Avian pathogenic Escherichia coli, a causative agent of avian colibacillosis, has been causing serious economic losses in the poultry industry. The increase in…”
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Efficacy of a new K3-specific bacteriophage for controlling Klebsiella pneumoniae in milk and its potential to disrupt biofilm formation
Published in Food control (01-09-2024)“…Klebsiella pneumoniae (K. pneumoniae) has caused huge economic loss in the dairy industry by inducing mastitis and even endanger public health through…”
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Evaluation of the immunogenicity and protective ability of a pili subunit, SBP2’, of Streptococcus suis serotype 2
Published in Research in veterinary science (01-07-2021)“…Streptococcus suis is an important zoonotic pathogen that leads to huge economic losses in the swine industry. Because of the enormous genetic and phenotypic…”
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Pan‐genome analysis of Streptococcus suis serotype 2 revealed genomic diversity among strains of different virulence
Published in Transboundary and emerging diseases (01-03-2021)“…Streptococcus suis (SS) is an emerging zoonotic pathogen that causes severe infections in swine and humans. Among the 33 known serotypes, serotype 2 is most…”
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Genome-wide association study identifies the virulence-associated marker in Streptococcus suis serotype 2
Published in Infection, genetics and evolution (01-08-2021)“…Streptococcus suis (S. suis) has been reported to be a highly invasive pathogen in swine, which causes severe infections like meningitis, arthritis and…”
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Identification of a phage-derived depolymerase specific for KL47 capsule of Klebsiella pneumoniae and its therapeutic potential in mice
Published in Virologica Sinica (01-08-2022)“…Klebsiella pneumoniae is one of the major pathogens causing global multidrug-resistant infections. Therefore, strategies for preventing and controlling the…”
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O145 may be emerging as a predominant serogroup of Avian pathogenic Escherichia coli (APEC) in China
Published in Veterinary microbiology (01-03-2022)“…•O145 may be emerging as a predominant serogroup of APEC in China.•The reasons for the prevalence and neglect of APEC O145 from the genetic…”
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