Search Results - "Guo, Cindy"
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High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue
Published in Cell (10-12-2020)“…We present deterministic barcoding in tissue for spatial omics sequencing (DBiT-seq) for co-mapping of mRNAs and proteins in a formaldehyde-fixed tissue slide…”
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Hyper-reflective dots in optical coherence tomography imaging and inflammation markers in diabetic retinopathy
Published in Journal of anatomy (01-10-2023)“…The aim of this study is to correlate small dot hyper-reflective foci (HRF) observed in spectral domain optical coherence tomography (SD-OCT) scans of an…”
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Effectiveness of a Binocular Video Game vs Placebo Video Game for Improving Visual Functions in Older Children, Teenagers, and Adults With Amblyopia: A Randomized Clinical Trial
Published in JAMA ophthalmology (01-02-2018)“…Binocular amblyopia treatment using contrast-rebalanced stimuli showed promise in laboratory studies and requires clinical trial investigation in a home-based…”
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Sustained Connexin43 Mimetic Peptide Release From Loaded Nanoparticles Reduces Retinal and Choroidal Photodamage
Published in Investigative ophthalmology & visual science (02-07-2018)“…To evaluate the long-term effect on inflammation and inflammasome activation of intravitreally delivered connexin43 mimetic peptide (Cx43MP) in saline or…”
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Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions
Published in Neural regeneration research (01-03-2021)“…Compounds that block the function of connexin and pannexin protein channels have been suggested to be valuable therapeutics for a range of diseases. Some of…”
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Connexin43 Mimetic Peptide Improves Retinal Function and Reduces Inflammation in a Light-Damaged Albino Rat Model
Published in Investigative ophthalmology & visual science (01-08-2016)“…Drugs that regulate connexin43 (Cx43) gap junction channels can reduce the spread of injury and improve functional outcomes after nervous system trauma. In the…”
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Short Chain Fatty Acids Modulate the Growth and Virulence of Pathosymbiont Escherichia coli and Host Response
Published in Antibiotics (Basel) (01-08-2020)“…Short chain fatty acids (SCFA), principally acetate, propionate, and butyrate, are produced by fermentation of dietary fibers by the gut microbiota. SCFA…”
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Optical treatment of amblyopia in older children and adults is essential prior to enrolment in a clinical trial
Published in Ophthalmic & physiological optics (01-03-2018)“…Purpose Optical treatment alone can improve visual acuity (VA) in children with amblyopia, thus clinical trials investigating additional amblyopia therapies…”
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Adherence to home-based videogame treatment for amblyopia in children and adults
Published in Clinical and experimental optometry (03-10-2021)“…Clinical relevance: Home-based videogame treatments are increasingly popular for amblyopia treatment. However, at-home treatments tend to be done in short…”
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Vinpocetine modulates metabolic activity and function during retinal ischemia
Published in American Journal of Physiology: Cell Physiology (01-05-2015)“…Vinpocetine protects against a range of degenerative conditions and insults of the central nervous system via multiple modes of action. Little is known,…”
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Gap junction proteins in the light-damaged albino rat
Published in Molecular vision (27-05-2014)“…Changes in connexin expression are associated with many pathological conditions seen in animal models and in humans. We hypothesized that gap junctions are…”
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Resolution of anisometropic amblyopia in a 48-year-old with refractive correction alone
Published in Clinical and experimental optometry (01-07-2017)Get full text
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Adenosine kinase inhibition in the cochlea delays the onset of age-related hearing loss
Published in Experimental gerontology (01-11-2011)“…This study was undertaken to determine the role of adenosine signalling in the development of age-related hearing loss (ARHL). We and others have shown…”
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Molecular and Phenotypic Characterization of Escherichia coli Associated with Granulomatous Colitis of Boxer Dogs
Published in Antibiotics (Basel) (25-08-2020)“…Invasive is causally associated with granulomatous colitis (GC) of Boxer dogs and French Bulldogs. The virulence determinants of GC are unclear. isolated from…”
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Binocular treatment of amblyopia using videogames (BRAVO): study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (18-10-2016)“…Amblyopia is a common neurodevelopmental disorder of vision that is characterised by visual impairment in one eye and compromised binocular visual function…”
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Post exposure administration of A(1) adenosine receptor agonists attenuates noise-induced hearing loss
Published in Hearing research (01-02-2010)“…Adenosine is a constitutive cell metabolite with a putative role in protection and regeneration in many tissues. This study was undertaken to determine if…”
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Post exposure administration of A1 adenosine receptor agonists attenuates noise-induced hearing loss
Published in Hearing research (01-02-2010)Get full text
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Role of adenosine kinase in cochlear development and response to noise
Published in Journal of neuroscience research (01-09-2010)“…Adenosine signalling has an important role in cochlear protection from oxidative stress. In most tissues, intracellular adenosine kinase (ADK) is the primary…”
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Adenosine amine congener mitigates noise-induced cochlear injury
Published in Purinergic signalling (01-06-2010)“…Hearing loss from noise exposure is a leading occupational disease, with up to 5% of the population at risk world-wide. Here, we present a novel purine-based…”
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A Robust and Reliable Test to Measure Stereopsis in the Clinic
Published in Investigative ophthalmology & visual science (01-03-2016)“…The purpose of this study was to develop a convenient test of stereopsis in the clinic that is both robust and reliable and capable of providing a measure of…”
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